Gene : GNPAT

Symbol :	GNPAT
Name/description :	glyceronephosphate O-acyltransferase
Synonyms :	DAPAT, DAP-AT, DHAPAT
Organism :	Homo sapiens
Peroxisomal Localization :	GO: peroxisome H Thai, et al.1997. FEBS Lett. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	GNPAT
Protein consensus sequence :	PTS1=0.0023; start position=669; end position=680; MESSSSSNSYFSVGPTSPSAVVLLYSKELKKWDEFEDILEERRHVSDLKFAMKCYTPLVYKGITPCKPIDIKCSVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNEEGIQKLQRAIQEHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYNLVPRYIPQKQSEDMHAFVTEVAYKMELLQIENMVLSPWTLIVAVLLQNRPSMDFDALVEKTLWLKGLTQAFGGFLIWPDNKPAEEVVPASILLHSNIASLVKDQVILKVDSGDSEVVDGLMLQHITLLMCSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKDFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVEKKKINNNCIFNVNEPATTKLEEMLGCKTPIGKPATAKL
Functional category(ies) :	Etherlipid and plasmalogens synthesis Lipid metabolism
Disease(s) :	Rhizomelic chondrodysplasia punctata type 2 (RCDP2)
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL SNPs (NCBI) Intron/Exon (Ace View: NCBI) Gene Expression (UCSC) Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	K Burdette, et al.1996. Neurology Late-onset generalized disorder of peroxisomes. Williams Williams, et al.1992. J. Lipid Res. HMG-CoA reductase inhibitors perturb fatty acid metabolism and induce peroxisomes in keratinocytes. Wolvetang Wolvetang, et al.1991. Biochim. Biophys. Acta Factors influencing the latency of the peroxisomal enzyme dihydroxyacetone-phosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts. H Pike, et al.1990. J. Pediatr. Congenital rubella syndrome associated with calcific epiphyseal stippling and peroxisomal dysfunction. Y Suzuki, et al.1988. J. Pediatr. Zellweger-like syndrome with detectable hepatic peroxisomes: a variant form of peroxisomal disorder.