Gene : PEX6

• Homo sapiens

• GO: peroxisome
  • T Yahraus, et al.1996. EMBO J.
  • Shigehiko Tamura, et al.2006. J. Biol. Chem.
• GFP: No experiment found
• Mass Spectrometry: No experiment found
• PeroxisomeDB annotation

• PEX6

PTS2=0.0042; start position=546; end position=554;

• Peroxisomal AAA-ATPases
• Peroxisome biogenesis (peroxins)

• Zellweger syndrome
• Neonatal adrenoleukodystrophy
• Infantile Refsum disease

• PTS prediction
• Blastp
• PsiBlast
• Alignment
• Phylogenetic tree [help]
• PhylomeDB

• Gene Summary (NCBI)
• Genome Browser (UCSC)
• Chromosomal Localization (NCBI)
• ENSEMBL
• SNPs (NCBI)
• Intron/Exon (Ace View: NCBI)
• Gene Expression (UCSC)
• Protein Properties (UCSC)
• Conserved Domains (NCBI)
• Orthologue Prediction (NCBI)

• Yik Yik, et al.2009. Hum. Mutat. Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders.
• Cindy Krause, et al.2006. Hum. Mutat. Identification of novel mutations in PEX2, PEX6, PEX10, PEX12, and PEX13 in Zellweger spectrum patients.
• Shigehiko Tamura, et al.2006. J. Biol. Chem. Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p.
• Satomi Furuki, et al.2006. J. Biol. Chem. Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.
• Annick Raas-Rothschild, et al.2002. Am. J. Hum. Genet. A PEX6-defective peroxisomal biogenesis disorder with severe phenotype in an infant, versus mild phenotype resembling Usher syndrome in the affected parents.
• S Chang, et al.1999. J. Cell. Sci. Metabolic control of peroxisome abundance.