Gene : LmjF35.1180

Symbol :	LmjF35.1180
Name/description :	NADH-dependent fumarate reductase
Synonyms :
Organism :	Leishmania major
Peroxisomal Localization :	GO: No Peroxisomal annotation GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	FR
Protein consensus sequence :	MADGKTSASVVAVDAESAAKERDAAARAMLQDGGVSPVGKAQLLKKGLVHTVPYTLKVVVADPKEMEKATADAEEVLQSAFQVVDTLLNSFNENSEVSRINRMPVGEEHQMSAALKHVMACCQKVYNSSRGAFDPAVGPLVRELREAAHKGKTVPAERVNDLLSKCTLNASFSIDMNRGMIARKHADAMLDLGGVNKGYGIDYTVERLNSLGYDDVFFEWGGDVRASGKNQSIQPWAVGIVRPPALADIRTVVPKDKRSFIRVVHLNNEAIATSGDYENLIETPASKVYSSTFDRASKNLLEPTEAGMAQVSVKCYSCMYADALATAALLKNDPAAVRRMLDNWRYVRDTVTDYTTYTREGERVAKMLEIATEDAEMRAKRIKGSLPARVIIVGGGLAGCSAAIEAANCGAQVILLEKEPKLGGNSAKATSGINAWGTRAQAKQGIMDGGKFFERDTHRSGKGGNCDPCLVKTLSVKSSDAVKWLSELGVPLTVLSQLGGASRKRCHRAPDKSDGTPVPVGFTIMKTLENHIVNNLSRHVTVMTGITVTALESTSHVRPDGVLVKHVTGVRLIQASGQSMVLNADAVILATGGFSNDHTPNSLLQQYAPQLSSFPTTNGVWATGDGVKMASKLGVALVDMDKVQLHPTGLIDPKDPSNRTKYLGPEALRGSGGVLLNKNGERFVNELDLRSVVSQAIIAQDNVYPGSGGSKFAYCVLNETAAKLFGKNFLGFYWNRLGLFQKSDSVAGLAKLIGCPEANVMATLKQYEELSSKKLNPCPLTGKNVFPCVLGTQGPYYVALITPSIHYTMGGCLISPSAEMQTKDNSGVTPVRRPILGLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDRAATILQKKNTGLSMTEWSTVVLREVREGGVYGAGSRVLRFNMPGALQKTGLALGQFIGIRGDWDGHRLIGYYSPITLPDDVGVIGILARADKGRLAEWISALQPGDAVEMKACGGLIIERRFADRHFFFRGHKIRKLALIGGGTGVAPMLQIVRAAVKKPFVDSIESIQFIYAAEDVSELTYRTLLESYEKEYGSEKFKCHFVLNNPPAQWTDGVGFVDTALLRSAVQAPSNDLLVAICGPPIMQRAVKGALKSLGYNMNLVRTVDETEPTSAKI
Functional category(ies) :	Carbohydrate Metabolism Glyoxylate and dicarboxylate metabolism
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help]
Gene Info:	Gene Summary (NCBI) Chromosomal Localization (NCBI) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Sébastien Besteiro, et al.2002. J. Biol. Chem. Succinate secreted by Trypanosoma brucei is produced by a novel and unique glycosomal enzyme, NADH-dependent fumarate reductase.