Gene : Pxmp3

Symbol :	Pxmp3
Name/description :	peroxisomal membrane protein 3
Synonyms :	Pex2, 35kDa, PMP35, D3Ertd138e
Organism :	Mus musculus
Peroxisomal Localization :	GO: No Peroxisomal annotation GFP: No experiment found Mass Spectrometry: Sebastian Wiese, et al.2007. Mol. Cell PROTEOMICS PeroxisomeDB annotation
Protein family :	PEX2
Protein consensus sequence :	PEX19=0.0019; start position=201; end position=210; PEX19=0.0027; start position=57; end position=66; PEX19=0.0048; start position=139; end position=148; PEX19=0.019; start position=149; end position=158; MTGKEENMQSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNIQYKNDSSLNLIYQPPSKTQKLWYAVCTIGGKWLEERCYDLFRNRHLASFGKAKQFMNFLVGLLKLGELINFLIFLQKGKFATLTERLLGIHSVFCKPQNMREVGFEYMNRELLWHGFAEFLIFLLPLINIQKLKAKLSSWCIPLTGAAGHDSTLGSSGKECALCGEWPTMPHTIGCEHVFCYYCVKSSFLFDIYFTCPKCGTEVHSVQPLKSGIEMSEVNAL
Functional category(ies) :	Peroxisome matrix protein import ZN RING proteins
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help]
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Kovacs Kovacs, et al.2009. J. Biol. Chem. Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress. Henk Keane, et al.2007. Hepatology Bile acid treatment alters hepatic disease and bile acid transport in peroxisome-deficient PEX2 Zellweger mice. Kovacs Kovacs, et al.2004. Mol. Cell. Biol. Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model. Faust Faust, et al.1997. J. Cell Biol. Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder. , et al.0. J. Mol. Neurosci. The peroxisome deficient PEX2 Zellweger mouse: pathologic and biochemical correlates of lipid dysfunction.