Protein familiy: LYS1

Organism : Cryptococcus neoformans
Protein family description: Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway.
Gene Description Genome localization
CND06290 saccharopine dehydrogenase (NAD+, L-lysine-forming) [Cryptococcus neoformans var. neoformans JEC21]
CNA02370 saccharopine dehydrogenase [Cryptococcus neoformans var. neoformans JEC21]

LYS1 sequence(s) for Cryptococcus neoformans and PTS predictions

  • CND06290
    PEX19=0.072; start position=352; end position=361;

  • MAATAPESATTSANTRPRQPIWLRCEKKPFEHRSALTPTTAKTLLDSNFDVYVEKDPQRIFDDREFEAVGCKIVPHNTWPSAPVDVPIIGLKELPE
    STDPLPHTHIQFAHCYKQQAGWNDVLRRFAQGKGTLYDLEFLEDPVSHRRVAAFGFHAGFAGAAAGALAFAAQQTQNGQGKLGELKPYPNEGEMVK
    EVSEALQGTKEGNKGVKVLIIGALGRCGSGAVDLFRKAGVAEENIIKWDMAETAKGGPFPEILDVDIFVNCIYLSKPIPKFITSEFIAEAGADRRL
    SVVVDVSCDTTNPHNPIPIYSINTTFPSPTVEVDTKGVGKRCTVISIDHLPTLLPREASEQFSTDLLPSLLQLPERQTAEVWVNAEKLFRTKLEEA
    RKYDEEQGIKA
  • CNA02370
    PEX19=0.029; start position=827; end position=836;

  • MRTLPLTRSPFITRRCLTTLGLRREDPSRIWERRTPLTPHAVQSLLADAKDQLKVEVESCKRRCFPDSLYSDAGAKIVPSLSKDVDVILGIKEPRL
    SDIRNLVEASKNEGKKRTWMMFSHTHKGQEYNIPLLSAFLHPTQTLIDHELLTAPAPGKDGKPQLKRVAAFGWFAGAVGAGEALSLTGLALLRRGL
    ATPLLSLSRPYSLGSLAAFKEALKKAGEEVKTSADLKGQEPIVIGVTGAGNVSSGATEMLNELGVVWVGPEDLADLRQSGSPNKIYACAITPASYL
    QRIEGGIFDKQEYYKSPDKYMSIFAAKIAPHLTTLINGVGWSKGFPRAITRPSLNKLIEKENGKQKLVAVQDITCDKEGGLEFVDQFTTVDNPYFE
    GPGDILISAIDILPTELAADASSYFSSALYPYIQGLLFPSGQGDKNDITETLSRAAIVKDGVLQSQHEWLGEKIEQWKTGGAVAPDSLKQEKLRKG
    GKKKVLLLGSGLVAGPAVDVFAARPDVHLIIASNNLAEGQSHIRGRPNVEAMALDVADDASMSEIVEEADIVVSLLPAPMHLRVAKHCLDHSRHLV
    TASYVSPELQALHSQAIEKDVIFLGECGLDPGIDSMAAMRILERAKREGKQVKSFVSWCGGLPELSASKVPLRYKFSWSPKAVLTAAQNDASYKLE
    GKHVKIPGNELLARRFPEVKLWDGLPLEGLANRDSMPYAKKYGLGPAEGLTDLFRGTLRYQGFSSLLESFRLLGLLRSDPLPGSPKSWTEFLSMTV
    ERELGLSKGLKGEDVSSAVQDLVGEGSKDVIRALKLFSLFPGSDTSLLPLPNLPTPSPIDFFAHLLSRKLAYLPDERDTCLLHHSFTISTPSGDTQ
    KVTASLRHMATPTQSSMSITVGKTLAFAALRIADGEVKVRGVTGPYEPEVWAGVLSSLEGAGVVIEEKWH