Protein familiy: FACL

Organism : Bos taurus
Protein family description: Acyl-CoA synthetase long-chain family.
Gene Description Genome localization
ENSBTAG00000017258 Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3). [Source:Uniprot/SWISSPROT;Acc:O95573] [from human gene ENSG00000123983] 14: 1822528-1853064
ENSBTAG00000018986 Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4). [Source:Uniprot/SWISSPROT;Acc:O60488] [from human gene ENSG00000068366] 30: 17135905-17166348
ACSF2 NULL 19: 28956567-28987655
ACSL1 Fatty-acid-Coenzyme A ligase long chain 2 (Fragment). [Source:Uniprot/SPTREMBL;Acc:Q6WRG0] 27: 10109384-10151095
ACSL5 Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5). [Source:Uniprot/SWISSPROT;Acc:Q9ULC5] [from human gene ENSG00000197142] 26: 21318815-21347443
ACSL6 Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6). [Source:Uniprot/SWISSPROT;Acc:Q9UKU0] [from human gene ENSG00000164398] 7: 20573624-20635940

FACL sequence(s) for Bos taurus and PTS predictions

  • ENSBTAG00000017258
    PEX19=0.0058; start position=23; end position=32;

  • MNNHGSSKPSSMKLKHTINPILLYFIQFIISLYTILTYIPYYFLSESRQEKSNRTKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFMHAK
    NKFKDKRLLGTREILNEEDEVQPNGKVFKKVILGSYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMVAAQACFMYNFQLVTLYAT
    LGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVRALGAKASMENKPLSKPAPSDIAVIMYTS
    GSTGIPKGVMISHSNIIAGITGMAERIPELGEKDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVP
    EIMDRIYKNVMNKVNEMSSFQRNLFILAYNYKMEQISKGHSTPLCDSFIFRKVRGLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES
    CGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKI
    IDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARRKGLHGTWEELCNSCEMENEVLKVLSEAAISASLE
    KFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
  • ENSBTAG00000018986
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • RNKHHFRSLATMKLKQSVLTIILLPIHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDH
    AVSKFGKKESLGTREVLSEENEMQPNGKVFKKLILGNYKWLNYLEVNRRVNNFGSGLTALGLKPKSTIAIFCETRAEWMIAAQTCFKYNFPLVTLY
    ATLGREAVVHGLNESEATYLITSVELLESKLKTALIDINCVKHIIYVDNKTINKAEYPEGFEIHSMQSVEELGSKPENLSVSPNRPTPSDLAIVMY
    TSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAA
    VPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTQRFMNVCFCCPVGQGYGLT
    ETCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTIHDKPNPRGEIVIGGKNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCL
    QIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQQKLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANTMK
    LERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK
  • ACSF2
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • MAVYVGMLRVARLCARSPRVLGARVGLSRVWQEARLWGVRPLSSGELDHTVPLPVGGFSYVQGHVGLHLSNKTVGRCLDATAQRVPDQEALVVHHE
    NIRLTFAQLKEEVDKAASGLLSIGLRKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYALKKVGCKALVFPKQFKTQQYYNILKQ
    ICPEVEKAQPGALKSQRLPDLTTVISVDAHLPGTLLLDEVVAAGSQEQNLTRLRHTQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNANMIG
    QRLRLHQKTPEESRVVLPSPLYHCLGSVGGTMVSLMHGVTLILCSPVFEGKKTLEAISRERGCFLYGTPTMFVDVLNQPDFSSYDISTMRGGVIAG
    SPAPPELIRAIINKLNMKELVVAYGTTENSPVTFMNFTEDTVEQKAESVGRVMPHTEAQIVNTETGTLTELNTPGELCIRGYCVMLGYWGEPQKTE
    EAIGQDKWYRTGDIAMMDEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPQVQEVQVVGVKDDRMGEEICACIRLKEGEKTTAEEIKAFCKGK
    ISHFKIPRYIVFVTNYPLTVSGKIQKFKLREQMEQHLNL
  • ACSL1
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • MQAHELFQYFRLPELLDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPRALKPPCDLAMQSVEVPGSDGARRSTLLDSDEPLVYFYDDVRTLYEGF
    QRGLHVSNNGPCLGSRKPDQPYEWLSYKQVEDMAECVGSALLHKGFKAAPDQFIGIFAQNRPEWVIIEQGCFTYSMVIVPLYDTLGTEAITYIINK
    AELSLVFVDKPEKANLLLEGVENKLIPCLKTIVLMDSYGSDLLERGKKCGVEIISMKAMEDLGRANRQKPKPPVPEDLAVICFTSGTTGNPKGAMI
    THRNVVSDCSAFVKMTENTFIPTSDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKALQPTIFPVVPRLLNRMFDRIFGQANTT
    LKRWLLDFASKRKEAELRSGIIRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTVAGDWTAGHV
    GPPMPCSIIKLVDVEEMNYLAAKGEGEVCVKGSNVFQGYLKDPVKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENI
    YQRSEPIAQVFVHGESLQAFLIAIVVPDVETLGTWAQKRGIVGSFEELCRNKDVKKGILEDMVRLGKESGLKPFEQVKGIYLHPELFSIDNGLLTP
    TMKAKRPELRNYFRSQIDELYSTIKV
  • ACSL5
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • TGLNFLLLFIKMLFIFNFLFSPLPTPALICILTFGAAIFLWLVNRPQPALPHVDLNKQSVGIEGGARRSICQKDNDLIRYYFSDAKTTYEIFQRGL
    AVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKPSQESFVGIFAQNRPEWVISEFACYTYSMVAVPLYDTLGAEAVIYIINKADIA
    MVICDTPQKALVLISNVEKGLTPGLKLVILMDPFEDDLKKRGEKCGVEILSLFDAENLGKENFRKPVPPAPEDLSIICFTSGTTGDPKGAMLTHAN
    IVSNASGFLKCMEGVFEPNPEDVCISYLPLAHMFERIVQVIVFSYGAKVGFFQGDIRLLPDDMRTLKPTLFPTVPRLLNKVYDKVQNEAKTPLKKF
    LLNLAVASKFREVKRGIIRRDSLWDKLIFGKIQESLGGKVRLLITGAAPISPPVLTFLRAALGCLVFEAYGQTECTAGCTVTLPGDWKSGHVGVPM
    ACNHVKLEDVPDMNYFAVNNEGEICIRGHNVFKGYLKEPEKTQETLDKDGWLHTGDIGRWLPNGTLKVIDRKKNIFKLAQGEYIAPEKIETVYIRS
    SLVSQIFVHGESLQSFLVGVVVPDPDALPPFAAKIGVKGSIEELCQNQTIKKAILEDMHKIGIDGGLKSFEQVKCIHLHPEPFSIENGLLTPTLKA
    KRGDLAKHFGTQIKSLYENTQ
  • ACSL6
    PEX19=0.039; start position=13; end position=22;

  • MLTFFLVSGGSLWLFSEFFLSLLEKMQTQEILRMLRLPELADLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALKPPCNLLMQSEEVEDSGGAR
    RSVIGDSPELFTHYYDDARTMYEVFHRGLRISGNGPCLGFRNPKQPYQWLSYQEVADRAEFLGSGLLQQNCKPCTDQFIGVFAQNRPEWIIAELAC
    YTYSMVVVPLYDTLGPGAVRYIINTADISTVIVDKPQKAVVLLEHVERKETPGLKLIILMEPFEEALKDRGQECGVVIKSMQDVEDCGQQNHCDPV
    PPKPSDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALH
    PTIFPVVPRLLNRMYDKIFSQADTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFHKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY
    EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWTSKGEGEICVRGPNVFKGYLKDPERTKEALDDDGWLHTGDIGKWLPTGTLK
    IIDRKKHIFKLAQGEYVAPEMIENIYIRSEPVAQVYVHGDSLKAFLVGIVVPDAEVMPSWAQKRGIEGTYAELCTNKELKKAILEDMVRLGQESGL
    HSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSTSM