Protein familiy: MVK

Organism : Caenorhabditis elegans
Protein family description: Mevalonate kinase (EC 2.7.1.36) (MK).
Gene Description Genome localization
Y42G9A.4 The Y42G9A.4 gene encodes an ortholog of the human gene MEVALONATE KINASE (MVK), which when mutated leads to mevalonicaciduria (OMIM:251170). [Source: WormBase] III: 6124125-6136217

MVK sequence(s) for Caenorhabditis elegans and PTS predictions

  • Y42G9A.4
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • MPVAAPEEHEKVVTVCGELVRSLDANGKEMVIRREVSVTETRESRDTSLKVEIPSEQEIELPVIVHDKPKLIKQEVSVVEPLELQESVESTELSVT
    SKESTEQLPSKDSLDSPSGSTSRAGSSVSATASPMHRNTTSQHGGLFVSAPGKIILFGEHAVVYGRTAIAGSIDLRTYVSLYTSADGRIYLSLPDL
    GVEKTWMLKDLLKAADRLAAEYPIEEDQPPSLEILVPIARKLSGSCEDQCGVQHLAILAFWYLLLGVAHRKRDLLAVKATVRFKLPSCVGLGSSGA
    YCVCIATSLLQTAGLIPPPSIVADEQGNLTWEEDHLDIIRKWATAAESLIHGRASGLDAAVCTFGGVASFKPGHRIEHLKNLPDLRVILVNSKVER
    NTARMVQTVKERLKKFPEVVDAMFGSIDAISLDAAKILHRPLLEENGGGDTGSTVQENGLGPFGGNMVEQDHHSLQPTRTASVRSSSLSSYVGGGK
    RNSSASVISATSEKGENVDTFSKLNDLCRINNQLLIALGVGHPKVDLICTTLARYGIHPKMTGAGGGGSVFAFLKPNTPQTLLDMIDGELRSHGFE
    VWQPPLGGPGVVEHQTRPELFQTPVSSTQCSTPASKHK