Protein familiy: PNC1

Organism : Saccharomyces cerevisiae
Protein family description: Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction.
Gene Description Genome localization
PNC1 Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span. [Source:Saccharomy VII: 427303-427953

PNC1 sequence(s) for Saccharomyces cerevisiae and PTS predictions

  • PNC1
     Non-significant PTS1, PTS2, PEX19 prediction reported

  • MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCV
    KNTWGSQLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTTVLLDYTRPI
    SDDPEVINKVKEELKAHNINVVDK