| Description : |
Peroxisome plays a key ROLE in the oxidation of fatty acids (FA) in all peroxisomal bearing organisms. The peroxisome FA substrates in mammals are mainly:
1) 1) very-long-chain fatty acids like C26:0, which are oxidized by the straight chain FA pathway
2) methyl-branched FA like phytanic acid, which are oxidized by the branched chain FA pathway
3) intermediates of the primary bile acids, which are oxidized by the di- and trihydroxycolestanoic acid oxidation pathway
4) and dicarboxylics acids oxidized by the long-chain dicarboxylics pathway. |