| Name : | Nicotinate and nicotinamide metabolism |
| Description : | NAD is an ubiquitous molecule that participates in many metabolic reactions. It also plays important ROLEs in transcriptional regulation, longevity, calorie-restriction-mediated life-span extension and age-associated diseases. In yeast, it has been shown that NAD affects longevity and transcriptional silencing. NAD is synthesised via two major pathways in both prokaryotic and eukaryotic systems: the de novo pathway and the salvage pathway. |
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