Functional category : Nicotinate and nicotinamide metabolism

Name : Nicotinate and nicotinamide metabolism
Description : NAD is an ubiquitous molecule that participates in many metabolic reactions. It also plays important ROLEs in transcriptional regulation, longevity, calorie-restriction-mediated life-span extension and age-associated diseases. In yeast, it has been shown that NAD affects longevity and transcriptional silencing. NAD is synthesised via two major pathways in both prokaryotic and eukaryotic systems: the de novo pathway and the salvage pathway.
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