Functional category : Branched chain fatty acid beta-oxidation

Name : Branched chain fatty acid beta-oxidation
Organism : Canis familiaris
Description : Branched chain fatty acids have a carbon scaffold with methyl branches. The enzymes that allow the properly beta-oxidation are:

a) ACOX2 (it belongs to the acyl-CoA oxidases family and carries on the first dehydrogenation),

ACOX3 (it belongs to the acyl-CoA oxidases family and is involved in branched chain FA oxidation only in rodentia. It carries on the first dehydrogenation),

c) HSD17B4 (D-PBE) (hydration and dehydrogenation again, rely on the bifunctional protein),

d) SCPX (Sterol carrier protein X carries on the thyolitic cleavage).
Gene(s) :
GENE PROTEIN FAMILY
ACOX1
ACOX2
ACOX3
HSD17B4
SCP2
Disease(s) :
Image(s) :
[top] Image description : Fatty acid oxidation

Fatty acid oxidation
THCA-SCFA-BCFA-oxidation.png

[top] Image description : Lipid metabolism

Lipid metabolism
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Lipid-metabolism.jpg