Functional category : Glyoxylate and dicarboxylate metabolism

Name : Glyoxylate and dicarboxylate metabolism
Organism : Yarrowia lipolytica
Description : Glyoxylate cycle allows the synthesis of macromolecules from dicarboxylates compounds such as ethanol and acetate. Metazoans in general, including humans, use glucose as the main carbon source and lack this cycle. Yeasts, plants and trypanosomatids have this cycle. In humans,the glyoxylate is a toxic metabolite wich undergoes oxalate formation. The oxalate precipitates as calcium oxalate with severe consequences for the tissues involved. Under normal conditions oxalate is converted to glycine by glyoxylate aminotransferase (AGT).
Gene(s) :
GENE PROTEIN FAMILY
YALI0D12661g
YALI0D16753g
YALI0D19140g
YALI0E02684g
YALI0E14190g
YALI0E15708g
YALI0E21307g
YALI0F04095g
Disease(s) : No diseases found
Image(s) :

[top] Image description : Glyoxylate and dicarboxylate metabolism

Glyoxylate and dicarboxylate metabolism
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Glyoxylate-and-dicarboxylate-metabolism.jpg