| PUBMED REFERENCES |
PROTEIN FAMILIES |
| Characterization of Arabidopsis 6-phosphogluconolactonase T-DNA insertion mutants reveals an essential role for the oxidative section of the plastidic pentose phosphate pathway in plant growth and development.[Pubmed]
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| Molecular characterization of the first two enzymes of the pentose-phosphate pathway of Trypanosoma brucei. Glucose-6-phosphate dehydrogenase and 6-phosphogluconolactonase.[Pubmed]
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| Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series.[Pubmed]
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| The Arabidopsis ALDP protein homologue COMATOSE is instrumental in peroxisomal acetate metabolism.[Pubmed]
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| Plant ATP-binding cassette transporters.[Pubmed]
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| Metabolite transport across the peroxisomal membrane.[Pubmed]
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| The peroxisomal ABC transporter family.[Pubmed]
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| Sucrose rescues seedling establishment but not germination of Arabidopsis mutants disrupted in peroxisomal fatty acid catabolism.[Pubmed]
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| Peroxisomal Acyl-CoA synthetase activity is essential for seedling development in Arabidopsis thaliana.[Pubmed]
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| Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP.[Pubmed]
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| Ped3p is a peroxisomal ATP-binding cassette transporter that might supply substrates for fatty acid beta-oxidation.[Pubmed]
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| The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage.[Pubmed]
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| X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism, ABC half-transporters and the complicated route to treatment.[Pubmed]
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| Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.[Pubmed]
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| Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model.[Pubmed]
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| Clinical, biochemical and genetic aspects and neuronal migration in peroxisome biogenesis disorders.[Pubmed]
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| ABC transporters in lipid transport.[Pubmed]
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| The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression.[Pubmed]
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| A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.[Pubmed]
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| RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: a model system to study PMP70 function.[Pubmed]
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| The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters.[Pubmed]
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| Mitochondrial ATP-binding cassette proteins.[Pubmed]
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| The peroxisomal lumen in Saccharomyces cerevisiae is alkaline.[Pubmed]
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| Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif.[Pubmed]
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| Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11.[Pubmed]
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| Adr1p-dependent regulation of the oleic acid-inducible yeast gene SPS19 encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase.[Pubmed]
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| Peroxisomal degradation of trans-unsaturated fatty acids in the yeast Saccharomyces cerevisiae.[Pubmed]
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| Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes.[Pubmed]
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| Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance.[Pubmed]
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| Primary structure of human PMP69, a putative peroxisomal ABC-transporter.[Pubmed]
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| A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.[Pubmed]
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| The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.[Pubmed]
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| Characterization and analysis of conserved motifs in a peroxisomal ATP-binding cassette transporter.[Pubmed]
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| PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.[Pubmed]
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| Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters.[Pubmed]
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| Characterization of Yarrowia lipolytica mutants affected in hydrophobic substrate utilization.[Pubmed]
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| Cholesterol-deprivation increases mono-unsaturated very long-chain fatty acids in skin fibroblasts from patients with X-linked adrenoleukodystrophy.[Pubmed]
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| ATP-binding and -hydrolysis activities of ALDP (ABCD1) and ALDRP (ABCD2), human peroxisomal ABC proteins, overexpressed in Sf21 cells.[Pubmed]
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| Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis.[Pubmed]
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| Novel insertion 496_497insG creating a stop codon D194X in a Chinese family with X-Linked adrenoleukodystrophy.[Pubmed]
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| Overexpression of a human and a fungal ABC transporter similarly suppresses the differentiation defects of a fungal peroxisomal mutant but introduces pleiotropic cellular effects.[Pubmed]
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| Functional characterization of the adrenoleukodystrophy protein (ALDP) and disease pathogenesis.[Pubmed]
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| Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly.[Pubmed]
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| ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: role in diagnosis and clinical correlations.[Pubmed]
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| Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes.[Pubmed]
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| Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters.[Pubmed]
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| Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins.[Pubmed]
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| Identification of a fourth half ABC transporter in the human peroxisomal membrane.[Pubmed]
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| Trypanosoma brucei glycosomal ABC transporters: identification and membrane targeting.[Pubmed]
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| Peroxisome proliferation, wound-activated responses and expression of peroxisome-associated genes are cross-regulated but uncoupled in Arabidopsis thaliana.[Pubmed]
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| The crystal structure of a plant 3-ketoacyl-CoA thiolase reveals the potential for redox control of peroxisomal fatty acid beta-oxidation.[Pubmed]
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| An Arabidopsis mutant disrupted in valine catabolism is also compromised in peroxisomal fatty acid beta-oxidation.[Pubmed]
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| Direct interaction between glyoxysomes and lipid bodies in cotyledons of the Arabidopsis thaliana ped1 mutant.[Pubmed]
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| Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings.[Pubmed]
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| Transport of peroxisomal proteins synthesized as large precursors in plants.[Pubmed]
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| The multifunctional protein AtMFP2 is co-ordinately expressed with other genes of fatty acid beta-oxidation during seed germination in Arabidopsis thaliana (L.) Heynh.[Pubmed]
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| A novel acyl-CoA oxidase that can oxidize short-chain acyl-CoA in plant peroxisomes.[Pubmed]
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| Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid.[Pubmed]
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| Peroxisomal beta-oxidation enzyme gene expression in the developing mouse brain.[Pubmed]
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| Morphological heterogeneity of peroxisomes in cultured mouse Leydig cells.[Pubmed]
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| Immunocytochemical demonstration of peroxisomes in cultured Leydig cells: a decrease in testosterone secretion precedes reduction of peroxisomes.[Pubmed]
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| Different accumulations of 3-ketoacyl-CoA thiolase precursor in peroxisomes of Chinese hamster ovary cells harboring a dysfunction in the PEX2 protein.[Pubmed]
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| Immunofluorescence technique for 100-nm-thick semithin sections of Epon-embedded tissues.[Pubmed]
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| Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat.[Pubmed]
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| Newly identified Chinese hamster ovary cell mutants are defective in biogenesis of peroxisomal membrane vesicles (Peroxisomal ghosts), representing a novel complementation group in mammals.[Pubmed]
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| Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity.[Pubmed]
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| Impairment of peroxisomal beta-oxidation system by endotoxin treatment.[Pubmed]
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| Post-translational import of 3-ketoacyl-CoA thiolase into rat liver peroxisomes in vitro.[Pubmed]
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| The impact of aging on enzyme proteins of rat liver peroxisomes: quantitative analysis by immunoblotting and immunoelectron microscopy.[Pubmed]
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| Signal peptide for peroxisomal targeting: replacement of an essential histidine residue by certain amino acids converts the amino-terminal presequence of peroxisomal 3-ketoacyl-CoA thiolase to a mitochondrial signal peptide.[Pubmed]
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| A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase.[Pubmed]
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| Mitochondrial metabolism of valproic acid.[Pubmed]
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| Immunoelectron microscopic study of a new D-amino acid oxidase-immunoreactive subcompartment in rat liver peroxisomes.[Pubmed]
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| Cloning and sequence determination of cDNA encoding a second rat liver peroxisomal 3-ketoacyl-CoA thiolase.[Pubmed]
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| Immunogold localization of peroxisomal enzymes in Epon-embedded liver tissue. Enhancement of sensitivity by etching with ethanolic sodium hydroxide.[Pubmed]
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| Immunocytochemical localization of peroxisomal enzymes in human liver biopsies.[Pubmed]
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| Synthesis of 3-ketoacyl-CoA thiolase of rat liver peroxisomes on free polyribosomes as a larger precursor. Induction of thiolase mRNA activity by clofibrate.[Pubmed]
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| Biosynthesis and intracellular transport of enzymes of peroxisomal beta-oxidation.[Pubmed]
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| Innermembrane association of three mitochondrial beta-oxidation enzymes revealed by immunoelectron microscopic technique.[Pubmed]
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| Immunocytochemical localization of two peroxisomal enzymes of lipid beta-oxidation in specific granules of rat eosinophils.[Pubmed]
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| Antifungal activity of Saccharomyces cerevisiae peroxisomal 3-ketoacyl-CoA thiolase.[Pubmed]
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| Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids.[Pubmed]
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| An n-alkane-responsive promoter element found in the gene encoding the peroxisomal protein of Candida tropicalis does not contain a C(6) zinc cluster DNA-binding motif.[Pubmed]
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| The 2.8 A crystal structure of peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: a five-layered alpha beta alpha beta alpha structure constructed from two core domains of identical topology.[Pubmed]
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| Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo.[Pubmed]
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| PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae.[Pubmed]
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| Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase.[Pubmed]
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| Genetic evaluation of physiological functions of thiolase isoenzymes in the n-alkalane-assimilating yeast Candida tropicalis.[Pubmed]
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| Immunoelectron microscopic observation of the behaviors of peroxisomal enzymes inducibly synthesized in an n-alkane-utilizable yeast cell, Candida tropicalis.[Pubmed]
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| Physiological roles of acetoacetyl-CoA thiolase in n-alkane-utilizable yeast, Candida tropicalis: possible contribution to alkane degradation and sterol biosynthesis.[Pubmed]
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| Genes encoding peroxisomal enzymes are not necessarily assigned on the same chromosome of an n-alkane-utilizable yeast Candida tropicalis.[Pubmed]
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| Peroxisomal acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase from an n-alkane-utilizing yeast, Candida tropicalis: purification and characterization.[Pubmed]
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| Occurrence and possible roles of acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase in peroxisomes of an n-alkane-grown yeast, Candida tropicalis.[Pubmed]
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| Cloning and expression in phospholipid containing cultures of the gene encoding the specific phosphatidylglycerol/phosphatidylinositol transfer protein from Aspergillus oryzae: evidence that the pg/pi-tp is tandemly arranged with the putative 3-ketoacyl-CoA thiolase gene.[Pubmed]
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| Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of leukotrienes.[Pubmed]
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| Reinvestigation of peroxisomal 3-ketoacyl-CoA thiolase deficiency: identification of the true defect at the level of d-bifunctional protein.[Pubmed]
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| Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene.[Pubmed]
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| Catalase-less peroxisomes. Implication in the milder forms of peroxisome biogenesis disorder.[Pubmed]
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| Biochemical features of a patient with Zellweger-like syndrome with normal PTS-1 and PTS-2 peroxisomal protein import systems: a new peroxisomal disease.[Pubmed]
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| Physiological role of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein.[Pubmed]
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| Prenatal diagnosis of peroxisomal disorders. Biochemical and immunocytochemical studies on peroxisomes in human amniocytes.[Pubmed]
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| Cytoplasmic catalase and ghostlike peroxisomes in the liver from a child with atypical chondrodysplasia punctata.[Pubmed]
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| Immunohistochemical expression of peroxisomal enzymes in developing human brain.[Pubmed]
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| Peroxisomal disorders in children: immunohistochemistry and neuropathology.[Pubmed]
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| Ultrastructure and immunocytochemistry of hepatic peroxisomes in rhizomelic chondrodysplasia punctata.[Pubmed]
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| Different intracellular localization of peroxisomal proteins in fibroblasts from patients with aberrant peroxisome assembly.[Pubmed]
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| Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts.[Pubmed]
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| Aberrant subcellular localization of peroxisomal 3-ketoacyl-CoA thiolase in the Zellweger syndrome and rhizomelic chondrodysplasia punctata.[Pubmed]
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| Molecular analysis of peroxisomal beta-oxidation enzymes in infants with peroxisomal disorders indicates heterogeneity of the primary defect.[Pubmed]
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| Biochemical and morphologic aspects of peroxisomes in the human rectal mucosa: diagnosis of Zellweger syndrome simplified by rectal biopsy.[Pubmed]
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| Detection of peroxisomes in human liver and kidney fixed with formalin and embedded in paraffin: the use of catalase and lipid beta-oxidation enzymes as immunocytochemical markers.[Pubmed]
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| Molecular analysis of peroxisomal beta-oxidation enzymes in infants with Zellweger syndrome and Zellweger-like syndrome: further heterogeneity of the peroxisomal disorder.[Pubmed]
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| Immunocytochemical demonstration of peroxisomal enzymes in human kidney biopsies.[Pubmed]
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| Characterization of Aspergillus nidulans peroxisomes by immunoelectron microscopy.[Pubmed]
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| Function of N-terminal import signals in trypanosome microbodies.[Pubmed]
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| Induction and subcellular localization of enzymes participating in propionate metabolism in Candida tropicalis.[Pubmed]
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| Identification and characterization of Arabidopsis indole-3-butyric acid response mutants defective in novel peroxisomal enzymes.[Pubmed]
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| IBR3, a novel peroxisomal acyl-CoA dehydrogenase-like protein required for indole-3-butyric acid response.[Pubmed]
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| Functional diversification of acyl-coenzyme A oxidases in jasmonic acid biosynthesis and action.[Pubmed]
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| Peroxisomal beta-oxidation--a metabolic pathway with multiple functions.[Pubmed]
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| Expression, purification and crystallization of two peroxisomal acyl-CoA oxidases from Arabidopsis thaliana.[Pubmed]
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| Arabidopsis mutants in short- and medium-chain acyl-CoA oxidase activities accumulate acyl-CoAs and reveal that fatty acid beta-oxidation is essential for embryo development.[Pubmed]
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| The Arabidopsis acyl-CoA oxidase gene family.[Pubmed]
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| Importance of sequences adjacent to the terminal tripeptide in the import of a peroxisomal Candida tropicalis protein in plant peroxisomes.[Pubmed]
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| Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets.[Pubmed]
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| Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism.[Pubmed]
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| Sequential ordered fatty acid alpha oxidation and Delta9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes.[Pubmed]
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| Expression of peroxisomal proteins provides clear evidence for the presence of peroxisomes in the male germ cell line GC1spg.[Pubmed]
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| Peroxisomal localization in the developing mouse cerebellum: implications for neuronal abnormalities related to deficiencies in peroxisomes.[Pubmed]
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| Lessons from knockout mice II: Mouse models for peroxisomal disorders with single protein deficiency.[Pubmed]
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| Studies on the metabolic fate of n-3 polyunsaturated fatty acids.[Pubmed]
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| Zellweger syndrome knockout mouse models challenge putative peroxisomal beta-oxidation involvement in docosahexaenoic acid (22:6n-3) biosynthesis.[Pubmed]
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| Detection of peroxisomal proteins and their mRNAs in serial sections of fetal and newborn mouse organs.[Pubmed]
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| Caloric restriction prevents oxidative damage induced by the carcinogen clofibrate in mouse liver.[Pubmed]
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| Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells).[Pubmed]
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| Peroxisomal impairment in Niemann-Pick type C disease.[Pubmed]
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| Aging-related decrease in liver peroxisomal fatty acid oxidation in control and clofibrate-treated mice. A biochemical study and mechanistic approach.[Pubmed]
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| Hepatic peroxisome proliferation in vitamin A-deficient mice without a simultaneous increase in peroxisomal acyl-CoA oxidase activity.[Pubmed]
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| Liver peroxisomal fatty acid oxidizing system during aging in control and clofibrate-treated mice.[Pubmed]
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| Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice.[Pubmed]
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| Perfluorooctanoic acid has persistent effects on peroxisome proliferation and related parameters in mouse liver.[Pubmed]
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| Reduced levels of peroxisomal enzymes in the kidney of the genetically obese (ob/ob) mouse. Contrast with liver.[Pubmed]
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| Localization of carnitine acyltransferases and acyl-CoA beta-oxidation enzymes in small intestinal microperoxisomes (peroxisomes) of normal and clofibrate treated mice.[Pubmed]
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| Detection of acyl-CoA beta-oxidation enzymes in peroxisomes (microperoxisomes) of mouse heart.[Pubmed]
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| Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury.[Pubmed]
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| Effect of dietary n-6/n-3 ratio on liver n-6/n-3 ratio and peroxisomal beta-oxidation activity in rats.[Pubmed]
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| Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase.[Pubmed]
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| Contribution of peroxisome-specific isoform of Lon protease in sorting PTS1 proteins to peroxisomes.[Pubmed]
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| Metabolism and short-term metabolic effects of conjugated linoleic acids in rat hepatocytes.[Pubmed]
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| Concerted action of leptin in regulation of fatty acid oxidation in skeletal muscle and liver.[Pubmed]
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| Intrinsic enoyl-CoA isomerase activity of rat acyl-CoA oxidase I.[Pubmed]
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| Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.[Pubmed]
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| Antioxidants attenuate diabetes-induced activation of peroxisomal functions in the rat kidney.[Pubmed]
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| Immunohistochemical localization of peroxisomal enzymes during rat embryonic development.[Pubmed]
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| Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences.[Pubmed]
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| The hypotriglyceridemic effect of dietary n-3 FA is associated with increased beta-oxidation and reduced leptin expression.[Pubmed]
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| Identification and cloning of two forms of liver peroxisomal fatty Acyl CoA Oxidase from the koala (Phascolarctos cinereus).[Pubmed]
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| Modulation of the peroxisomal gene expression pattern by dehydroepiandrosterone and vitamin D: therapeutic implications.[Pubmed]
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| Analyses in transfected cells and in vitro of a putative peroxisomal targeting signal of rat liver serine:pyruvate aminotransferase.[Pubmed]
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| Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase.[Pubmed]
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| Peroxisomes are formed from complex membrane structures in PEX6-deficient CHO cells upon genetic complementation.[Pubmed]
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| Localization of mRNAs encoding peroxisomal proteins in cell culture by non-radioactive in situ hybridization. Comparison of rat and human hepatoma cells and their responses to two divergent hypolipidemic drugs.[Pubmed]
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| Effect of sesamin on mitochondrial and peroxisomal beta-oxidation of arachidonic and eicosapentaenoic acids in rat liver.[Pubmed]
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| Hsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1.[Pubmed]
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| Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes.[Pubmed]
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| Peroxisomal lipid degradation via beta- and alpha-oxidation in mammals.[Pubmed]
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| Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status.[Pubmed]
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| Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.[Pubmed]
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| Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids.[Pubmed]
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| Role and organization of peroxisomal beta-oxidation.[Pubmed]
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| Induction by perfluorinated fatty acids with different carbon chain length of peroxisomal beta-oxidation in the liver of rats.[Pubmed]
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| Gene expression of peroxisomal beta-oxidation enzymes in rat brain.[Pubmed]
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| Cytochrome P450, peroxisome proliferation, and cytoplasmic fatty acid-binding protein content in liver, heart and kidney of the diabetic rat.[Pubmed]
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| New insights in peroxisomal beta-oxidation. Implications for human peroxisomal disorders.[Pubmed]
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| Impairment of peroxisomal structure and function in rat liver allograft rejection: prevention by cyclosporine.[Pubmed]
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| Comparative effects of alpha- and gamma-linolenic acids on rat liver fatty acid oxidation.[Pubmed]
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| Biogenesis of peroxisomes in fetal liver.[Pubmed]
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| Molecular cloning and expression of cDNA encoding 3alpha,7alpha,12alpha-trihydroxy-5beta-chole stanoyl-CoA oxidase from rabbit liver.[Pubmed]
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| Effect of gemfibrozil on centrifugal behavior of rat peroxisomes and activities of peroxisomal enzymes involved in lipid metabolism.[Pubmed]
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| Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid.[Pubmed]
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| Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.[Pubmed]
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| In vitro association with peroxisomes and conformational change of peroxisomal serine:pyruvate/alanine:glyoxylate aminotransferase in rat and human livers.[Pubmed]
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| Stereoisomeric inversion of (25R)- and (25S)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acids in rat liver peroxisome.[Pubmed]
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| Novel peroxisomal populations in subcellular fractions from rat liver. Implications for peroxisome structure and biogenesis.[Pubmed]
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| Activity measurements of acyl-CoA oxidases in human liver.[Pubmed]
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| Peroxisomal beta-oxidation. Purification of four novel 3-hydroxyacyl-CoA dehydrogenases from rat liver peroxisomes.[Pubmed]
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| Estimation of peroxisomal beta-oxidation in rat heart by a direct assay of acyl-CoA oxidase.[Pubmed]
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| Zonal heterogeneity of peroxisomal enzymes in rat liver: differential induction by three divergent hypolipidemic drugs.[Pubmed]
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| Urate oxidase is imported into peroxisomes recognizing the C-terminal SKL motif of proteins.[Pubmed]
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| Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system.[Pubmed]
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| Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase.[Pubmed]
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| Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney.[Pubmed]
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| An intimate collaboration between peroxisomes and lipid bodies.[Pubmed]
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| Functional similarity between the peroxisomal PTS2 receptor binding protein Pex18p and the N-terminal half of the PTS1 receptor Pex5p.[Pubmed]
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| Alpha-Ketoglutarate dehydrogenase and lipoic acid synthase are important for the functioning of peroxisomes of Saccharomyces cerevisiae.[Pubmed]
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| Futile cycling of intermediates of fatty acid biosynthesis toward peroxisomal beta-oxidation in Saccharomyces cerevisiae.[Pubmed]
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| Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.[Pubmed]
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| Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae.[Pubmed]
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| Oxygen and haem regulate the synthesis of peroxisomal proteins: catalase A, acyl-CoA oxidase and Pex1p in the yeast Saccharomyces cerevisiae; the regulation of these proteins by oxygen is not mediated by haem.[Pubmed]
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| Analysis of the peroxisomal acyl-CoA oxidase gene product from Pichia pastoris and determination of its targeting signal.[Pubmed]
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| Pex18p and Pex21p, a novel pair of related peroxins essential for peroxisomal targeting by the PTS2 pathway.[Pubmed]
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| Regulation of peroxisomal fatty acyl-CoA oxidase in the yeast. Saccharomyces cerevisiae.[Pubmed]
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| A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of beta-oxidation enzymes in Saccharomyces cerevisiae.[Pubmed]
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| Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants.[Pubmed]
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| Identification of a yeast peroxisomal member of the family of AMP-binding proteins.[Pubmed]
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| Purification, identification, and properties of a Saccharomyces cerevisiae oleate-activated upstream activating sequence-binding protein that is involved in the activation of POX1.[Pubmed]
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| Peb1p (Pas7p) is an intraperoxisomal receptor for the NH2-terminal, type 2, peroxisomal targeting sequence of thiolase: Peb1p itself is targeted to peroxisomes by an NH2-terminal peptide.[Pubmed]
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| Maintenance of the peroxisomal compartment in glucose-repressed and anaerobically grown Saccharomyces cerevisiae cells.[Pubmed]
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| Expression of the FOX1 gene of Saccharomyces cerevisiae is regulated by carbon source, but not by the known glucose repression genes.[Pubmed]
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| PEB1 (PAS7) in Saccharomyces cerevisiae encodes a hydrophilic, intra-peroxisomal protein that is a member of the WD repeat family and is essential for the import of thiolase into peroxisomes.[Pubmed]
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| Three peroxisome protein packaging pathways suggested by selective permeabilization of yeast mutants defective in peroxisome biogenesis.[Pubmed]
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| Peroxisomal disorders. Neurodevelopmental and biochemical aspects.[Pubmed]
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| A negative regulating element controlling transcription of the gene encoding acyl-CoA oxidase in Saccharomyces cerevisiae.[Pubmed]
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| Study on stereospecificity of enzyme reaction related to peroxisomal bile acid synthesis in rat liver.[Pubmed]
|
|
| Regulation of transcription of the gene coding for peroxisomal 3-oxoacyl-CoA thiolase of Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisomes in Saccharomyces cerevisiae: immunofluorescence analysis and import of catalase A into isolated peroxisomes.[Pubmed]
|
|
| Participation of the peroxisomal beta-oxidation system in the chain-shortening of PCA16, a metabolite of the cytosine arabinoside prodrug, YNKO1, in rat liver.[Pubmed]
|
|
| Acyl-CoA synthetase and the peroxisomal enzymes of beta-oxidation in human liver. Quantitative analysis of their subcellular localization.[Pubmed]
|
|
| Regulation of peroxisomal proteins and organelle proliferation by multiple carbon sources in the methylotrophic yeast, Candida boidinii.[Pubmed]
|
|
| Acyl-CoA oxidase contains two targeting sequences each of which can mediate protein import into peroxisomes.[Pubmed]
|
|
| Import of the carboxy-terminal portion of acyl-CoA oxidase into peroxisomes of Candida tropicalis.[Pubmed]
|
|
| Efficient association of in vitro translation products with purified stable Candida tropicalis peroxisomes.[Pubmed]
|
|
| Peroxisomal acyl-coenzyme A oxidase multigene family of the yeast Candida tropicalis; nucleotide sequence of a third gene and its protein product.[Pubmed]
|
|
| Induction, identification, and cell-free translation of mRNAs coding for peroxisomal proteins in Candida tropicalis.[Pubmed]
|
|
| Two acyl-coenzyme A oxidases in peroxisomes of the yeast Candida tropicalis: primary structures deduced from genomic DNA sequence.[Pubmed]
|
|
| Cloning of cDNA coding for peroxisomal acyl-CoA oxidase from the yeast Candida tropicalis pK233.[Pubmed]
|
|
| Stereochemistry of dehydrogenation catalyzed by Acyl-CoA oxidase.[Pubmed]
|
|
| The effect of clofibrate on amphibian hepatic peroxisomes.[Pubmed]
|
|
| Effect of acyl-CoA oxidase activity on the accumulation of gamma-decalactone by the yeast Yarrowia lipolytica: a factorial approach.[Pubmed]
|
|
| A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane.[Pubmed]
|
|
| Observation of the Yarrowia lipolytica peroxisome-vacuole dynamics by fluorescence microscopy with a single filter set.[Pubmed]
|
|
| Peroxisome division in the yeast Yarrowia lipolytica is regulated by a signal from inside the peroxisome.[Pubmed]
|
|
| Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica.[Pubmed]
|
|
| Cloning, sequencing, and characterization of five genes coding for acyl-CoA oxidase isozymes in the yeast Yarrowia lipolytica.[Pubmed]
|
|
| Pex20p of the yeast Yarrowia lipolytica is required for the oligomerization of thiolase in the cytosol and for its targeting to the peroxisome.[Pubmed]
|
|
| Effects of WY-14643 on peroxisomal enzyme activity and hormone secretion in immortalized human trophoblast cells.[Pubmed]
|
|
| Peroxisomal acyl-CoA-oxidase deficiency: two new cases.[Pubmed]
|
|
| PTS1-independent sorting of peroxisomal matrix proteins by Pex5p.[Pubmed]
|
|
| Aberrant peroxisome morphology in peroxisomal beta-oxidation enzyme deficiencies.[Pubmed]
|
|
| Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer.[Pubmed]
|
|
| Peroxisomes, lipid metabolism, and peroxisomal disorders.[Pubmed]
|
|
| Carnitine prevents cyclic GMP-induced inhibition of peroxisomal enzyme activities.[Pubmed]
|
|
| Hyperpipecolic acidaemia: a diagnostic tool for peroxisomal disorders.[Pubmed]
|
|
| PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells.[Pubmed]
|
|
| Pex5p binding affinities for canonical and noncanonical PTS1 peptides.[Pubmed]
|
|
| Genetic-dependency of peroxisomal cell functions - emerging aspects.[Pubmed]
|
|
| Evidence for increased oxidative stress in peroxisomal D-bifunctional protein deficiency.[Pubmed]
|
|
| Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders.[Pubmed]
|
|
| Stereochemistry of the peroxisomal branched-chain fatty acid alpha- and beta-oxidation systems in patients suffering from different peroxisomal disorders.[Pubmed]
|
|
| Hitchhiking fads en route to peroxisomes.[Pubmed]
|
|
| Peroxisomal acyl CoA oxidase deficiency.[Pubmed]
|
|
| Temperature sensitive acyl-CoA oxidase import in group A peroxisome biogenesis disorders.[Pubmed]
|
|
| Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis.[Pubmed]
|
|
| Fibroblast studies documenting a case of peroxisomal 2-methylacyl-CoA racemase deficiency: possible link between racemase deficiency and malabsorption and vitamin K deficiency.[Pubmed]
|
|
| Clinical consequences of defects in peroxisomal beta-oxidation.[Pubmed]
|
|
| Hepatic peroxisomes in isolated hyperpipecolic acidaemia: evidence supporting its classification as a single peroxisomal enzyme deficiency.[Pubmed]
|
|
| Restoration of biochemical function of the peroxisome in the temperature-sensitive mild forms of peroxisome biogenesis disorder in humans.[Pubmed]
|
|
| Immunocytochemical investigation of catalase and peroxisomal lipid beta-oxidation enzymes in human hepatocellular tumors and liver cirrhosis.[Pubmed]
|
|
| Functional heterogeneity of C-terminal peroxisome targeting signal 1 in PEX5-defective patients.[Pubmed]
|
|
| Metabolic control of peroxisome abundance.[Pubmed]
|
|
| Peroxisomal very long chain fatty acid beta-oxidation activity is determined by the level of adrenodeukodystrophy protein (ALDP) expression.[Pubmed]
|
|
| Human long chain, very long chain and medium chain acyl-CoA dehydrogenases are specific for the S-enantiomer of 2- methylpentadecanoyl-CoA.[Pubmed]
|
|
| Newly identified Chinese hamster ovary cell mutants defective in peroxisome biogenesis represent two novel complementation groups in mammals.[Pubmed]
|
|
| Incidence of peroxisomal disorders in Japan.[Pubmed]
|
|
| Distinction between peroxisomal bifunctional enzyme and acyl-CoA oxidase deficiencies.[Pubmed]
|
|
| Immunoblot analysis of peroxisomal proteins in liver and fibroblasts from patients.[Pubmed]
|
|
| Novel subtype of peroxisomal acyl-CoA oxidase deficiency and bifunctional enzyme deficiency with detectable enzyme protein: identification by means of complementation analysis.[Pubmed]
|
|
| Mitochondrial short-chain acyl-CoA dehydrogenase of human liver and kidney can function as an oxidase.[Pubmed]
|
|
| Peroxisomal oxidation of the steroid side chain in bile acid formation.[Pubmed]
|
|
| Morphometry of peroxisomes and immunolocalization of peroxisomal proteins in the liver of patients with generalised peroxisomal disorders.[Pubmed]
|
|
| The activity and subcellular distribution of the peroxisomal enzyme acyl-CoA oxidase in human blood platelets.[Pubmed]
|
|
| Peroxisomal enzymes in normal and tumoral human breast.[Pubmed]
|
|
| Neonatal seizures and severe hypotonia in a male infant suffering from a defect in peroxisomal beta-oxidation.[Pubmed]
|
|
| Peroxisomes in human colon carcinomas. A cytochemical and biochemical study.[Pubmed]
|
|
| Induction of beta-oxidation enzymes and microbody proliferation in Aspergillus nidulans.[Pubmed]
|
|
| The beta-oxidation system in catalase-free microbodies of the filamentous fungus Neurospora crassa. Purification of a multifunctional protein possessing 2-enoyl-CoA hydratase, L-3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxyacyl-CoA epimerase activities.[Pubmed]
|
|
| How proteins get into microbodies (peroxisomes, glyoxysomes, glycosomes).[Pubmed]
|
|
| The regulation of peroxisomal enzyme systems of Tetrahymena pyriformis by fatty acid composition, glucose and oxygen in the medium.[Pubmed]
|
|
| RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders.[Pubmed]
|
|
| Plasmalogen assembly: a key flavoenzyme.[Pubmed]
|
|
| Immunological localization and tissue distribution of alkyldihydroxyacetonephosphate synthase and deficiency of the enzyme in peroxisomal disorders.[Pubmed]
|
|
| Impaired membrane traffic in defective ether lipid biosynthesis.[Pubmed]
|
|
| Synthesis of plasmalogens in eye lens epithelial cells.[Pubmed]
|
|
| Peroxisomes and ether lipid biosynthesis in rat testis and epididymis.[Pubmed]
|
|
| Exclusive localization in peroxisomes of dihydroxyacetone phosphate acyltransferase and alkyl-dihydroxyacetone phosphate synthase in rat liver.[Pubmed]
|
|
| Kinetic studies of alkyl-dihydroxyacetone-phosphate (alkyl-glycerone-phosphate) synthase in peroxisomes of rat liver.[Pubmed]
|
|
| Topography of ether phospholipid biosynthesis.[Pubmed]
|
|
| Dihydroxyacetone phosphate acyltransferase and alkyldihydroxyacetone phosphate synthase activities in rat liver subcellular fractions and human skin fibroblasts.[Pubmed]
|
|
| Rat liver dihydroxyacetone-phosphate acyltransferase: enzyme characteristics and localization studies.[Pubmed]
|
|
| Distribution of alkylglycerone-phosphate synthase in subcellular fractions of rat liver.[Pubmed]
|
|
| Glycerolipid biosynthesis in peroxisomes via the acyl dihydroxyacetone phosphate pathway.[Pubmed]
|
|
| Subcellular distribution of alkyl dihydroxyacetone phosphate synthase in rat liver.[Pubmed]
|
|
| Alkyl-dihydroxyacetonephosphate synthase.[Pubmed]
|
|
| Caenorhabditis elegans has a single pathway to target matrix proteins to peroxisomes.[Pubmed]
|
|
| Isolation and characterization of mutant animal cell line defective in alkyl-dihydroxyacetonephosphate synthase: localization and transport of plasmalogens to post-Golgi compartments.[Pubmed]
|
|
| Stability of alkyl-dihydroxyacetonephosphate synthase in human control and peroxisomal disorder fibroblasts.[Pubmed]
|
|
| Ether lipid biosynthesis: alkyl-dihydroxyacetonephosphate synthase protein deficiency leads to reduced dihydroxyacetonephosphate acyltransferase activities.[Pubmed]
|
|
| In vitro processing of the human alkyl-dihydroxyacetonephosphate synthase precursor.[Pubmed]
|
|
| Alkyl-dihydroxyacetone phosphate synthase and dihydroxyacetone phosphate acyltransferase form a protein complex in peroxisomes.[Pubmed]
|
|
| Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency.[Pubmed]
|
|
| Alkyl-dihydroxyacetonephosphate synthase.[Pubmed]
|
|
| Non-rhizomelic and rhizomelic chondrodysplasia punctata within a single complementation group.[Pubmed]
|
|
| Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver.[Pubmed]
|
|
| Genetic and biochemical heterogeneity in patients with the rhizomelic form of chondrodysplasia punctata--a complementation study.[Pubmed]
|
|
| Properties of the enzymes catalyzing the biosynthesis of lysophosphatidate and its ether analog in cultured fibroblasts from Zellweger syndrome patients and normal controls.[Pubmed]
|
|
| Infantile Refsum disease: deficiency of catalase-containing particles (peroxisomes), alkyldihydroxyacetone phosphate synthase and peroxisomal beta-oxidation enzyme proteins.[Pubmed]
|
|
| Alkyl dihydroxyacetone phosphate synthase in human fibroblasts and its deficiency in Zellweger syndrome.[Pubmed]
|
|
| Alkyl dihydroxyacetone phosphate synthase in glycosomes of Trypanosoma brucei.[Pubmed]
|
|
| Control of oxalate formation from L-hydroxyproline in liver mitochondria.[Pubmed]
|
|
| Mitochondrial targeting signal-induced conformational change and repression of the peroxisomal targeting signal of the precursor for rat liver serine:pyruvate/alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Flux of the L-serine metabolism in rabbit, human, and dog livers. Substantial contributions of both mitochondrial and peroxisomal serine:pyruvate/alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Fidelity of translation initiation of mRNA for the precursor of rat mitochondrial serine:pyruvate/alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Immunocytochemical demonstration of serine: pyruvate amino-transferase in peroxisomes and mitochondria of rat kidney.[Pubmed]
|
|
| Fine localization of serine:pyruvate aminotransferase in rat hepatocytes revealed by a post-embedding immunocytochemical technique.[Pubmed]
|
|
| Peroxisomal localization of serine:pyruvate aminotransferase in human liver.[Pubmed]
|
|
| ATP-dependent degradation of a mutant serine: pyruvate/alanine:glyoxylate aminotransferase in a primary hyperoxaluria type 1 case.[Pubmed]
|
|
| Immunocytochemical localization of serine: pyruvate aminotransferase in peroxisomes of the human liver parenchymal cells.[Pubmed]
|
|
| Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis.[Pubmed]
|
|
| Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana.[Pubmed]
|
|
| Peroxisomal alanine : glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana.[Pubmed]
|
|
| Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.[Pubmed]
|
|
| Peroxisomal and mitochondrial targeting of serine:pyruvate/alanine:glyoxylate aminotransferase in rat liver.[Pubmed]
|
|
| Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the feline gene.[Pubmed]
|
|
| Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the marmoset and rabbit genes.[Pubmed]
|
|
| Dimethylarginine:pyruvate aminotransferase in rats. Purification, properties, and identity with alanine:glyoxylate aminotransferase 2.[Pubmed]
|
|
| Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon.[Pubmed]
|
|
| Alanine: glyoxylate aminotransferase 1 is present in the peroxisomes of guinea pig kidney.[Pubmed]
|
|
| The effect of vitamin B6 deficiency on alanine: glyoxylate aminotransferase isoenzymes in rat liver.[Pubmed]
|
|
| Purification and properties of peroxisomal pyruvate (glyoxylate) aminotransferase from rat liver.[Pubmed]
|
|
| Subcellular distribution of pyruvate (glyoxylate) aminotransferases in rat liver.[Pubmed]
|
|
| The peroxisomal targeting sequence type 1 receptor, Pex5p, and the peroxisomal import efficiency of alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Genetic heterogeneity in primary hyperoxaluria type 1: impact on diagnosis.[Pubmed]
|
|
| Peroxisomal import of human alanine:glyoxylate aminotransferase requires ancillary targeting information remote from its C terminus.[Pubmed]
|
|
| Molecular basis for the dual mitochondrial and cytosolic localization of alanine:glyoxylate aminotransferase in amphibian liver cells.[Pubmed]
|
|
| Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation.[Pubmed]
|
|
| Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis.[Pubmed]
|
|
| Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli.[Pubmed]
|
|
| Characterization of peroxisomal targeting signals on alanine: glyoxylate aminotransferase.[Pubmed]
|
|
| Primary hyperoxaluria type 1: AGT mistargeting highlights the fundamental differences between the peroxisomal and mitochondrial protein import pathways.[Pubmed]
|
|
| High incidence of hyperoxaluria in generalized peroxisomal disorders.[Pubmed]
|
|
| Cellular transfection to deliver alanine-glyoxylate aminotransferase to hepatocytes: a rational gene therapy for primary hyperoxaluria-1 (PH-1).[Pubmed]
|
|
| Molecular aetiology of primary hyperoxaluria type 1.[Pubmed]
|
|
| Diet and the frequency of the alanine:glyoxylate aminotransferase Pro11Leu polymorphism in different human populations.[Pubmed]
|
|
| Glycolate and glyoxylate metabolism in HepG2 cells.[Pubmed]
|
|
| Molecular aetiology of primary hyperoxaluria and its implications for clinical management.[Pubmed]
|
|
| Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1.[Pubmed]
|
|
| Primary hyperoxaluria type 1 in the Canary Islands: a conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Correction of an enzyme trafficking defect in hereditary kidney stone disease in vitro.[Pubmed]
|
|
| Alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting in human hereditary kidney stone disease.[Pubmed]
|
|
| Functional synergism between the most common polymorphism in human alanine:glyoxylate aminotransferase and four of the most common disease-causing mutations.[Pubmed]
|
|
| Effect of N-terminal alpha-helix formation on the dimerization and intracellular targeting of alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| The molecular basis of alanine: glyoxylate aminotransferase mistargeting: the most common single cause of primary hyperoxaluria type 1.[Pubmed]
|
|
| Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene.[Pubmed]
|
|
| A unique molecular basis for enzyme mistargeting in primary hyperoxaluria type 1.[Pubmed]
|
|
| Variable peroxisomal and mitochondrial targeting of alanine: glyoxylate aminotransferase in mammalian evolution and disease.[Pubmed]
|
|
| Context dependency of the PTS1 motif in human alanine: glyoxylate aminotransferase 1.[Pubmed]
|
|
| Primary hyperoxaluria type 1 caused by peroxisome-to-mitochondrion mistargeting of alanine: glyoxylate aminotransferase.[Pubmed]
|
|
| Inhibition of alanine:glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1.[Pubmed]
|
|
| Hyperoxaluria with hyperglycoluria not due to alanine:glyoxylate aminotransferase defect: a novel type of primary hyperoxaluria.[Pubmed]
|
|
| Molecular basis of the variable mitochondrial and peroxisomal localisation of alanine-glyoxylate aminotransferase.[Pubmed]
|
|
| Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.[Pubmed]
|
|
| Immunocytochemical localization of peroxisomal proteins in human liver and kidney.[Pubmed]
|
|
| Advances in the enzymology and molecular genetics of primary hyperoxaluria type 1. Prospects for gene therapy.[Pubmed]
|
|
| A new type of peroxisomal disorder with variable expression in liver and fibroblasts.[Pubmed]
|
|
| Heterogeneity of peroxisomes in human hepatoblastoma cell line HepG2. Evidence of distinct subpopulations.[Pubmed]
|
|
| Molecular characterization and clinical use of a polymorphic tandem repeat in an intron of the human alanine:glyoxylate aminotransferase gene.[Pubmed]
|
|
| Primary hyperoxaluria type 1: genotypic and phenotypic heterogeneity.[Pubmed]
|
|
| Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation.[Pubmed]
|
|
| Primary hyperoxaluria type 1 and peroxisome-to-mitochondrion mistargeting of alanine:glyoxylate aminotransferase.[Pubmed]
|
|
| Success of kidney transplantation in oxalosis is unrelated to residual hepatic enzyme activity.[Pubmed]
|
|
| Alanine glyoxylate aminotransferase deficiency: biochemical and molecular genetic lessons from the study of a human disease.[Pubmed]
|
|
| Structure-function relationships in the peroxisome: implications for human disease.[Pubmed]
|
|
| An intronic duplication in the alanine: glyoxylate aminotransferase gene facilitates identification of mutations in compound heterozygote patients with primary hyperoxaluria type 1.[Pubmed]
|
|
| Molecular and clinical heterogeneity in primary hyperoxaluria type 1.[Pubmed]
|
|
| Subcellular distribution of hepatic alanine:glyoxylate aminotransferase in various mammalian species.[Pubmed]
|
|
| Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.[Pubmed]
|
|
| Immunocytochemical localization of human hepatic alanine: glyoxylate aminotransferase in control subjects and patients with primary hyperoxaluria type 1.[Pubmed]
|
|
| Immunological heterogeneity of hepatic alanine:glyoxylate aminotransferase in primary hyperoxaluria type 1.[Pubmed]
|
|
| Alanine glyoxylate aminotransferase and the urinary excretion of oxalate and glycollate in hyperoxaluria type I and the Zellweger syndrome.[Pubmed]
|
|
| Genetic diseases caused by peroxisomal dysfunction. New findings in clinical and biochemical studies.[Pubmed]
|
|
| Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes in different mammalian species.[Pubmed]
|
|
| Subcellular localization of superoxide dismutase in rat liver.[Pubmed]
|
|
| Mitochondria and peroxisomes from the cellular slime mould Dictyostelium discoideum. Isolation techniques and urate oxidase association with peroxisomes.[Pubmed]
|
|
| Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei.[Pubmed]
|
|
| The occurrence of glycosomes (microbodies) in the promastigote stage of four major Leishmania species.[Pubmed]
|
|
| Subcellular localization and physiological role of alpha-methylacyl-CoA racemase.[Pubmed]
|
|
| Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans.[Pubmed]
|
|
| Purification and characterization of an alpha-methylacyl-CoA racemase from human liver.[Pubmed]
|
|
| Peroxisomal disorders affecting phytanic acid alpha-oxidation: a review.[Pubmed]
|
|
| Expression profiling identifies a novel alpha-methylacyl-CoA racemase exon with fumarate hydratase homology.[Pubmed]
|
|
| Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy.[Pubmed]
|
|
| Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency.[Pubmed]
|
|
| Peroxisomal ATP import is essential for seedling development in Arabidopsis thaliana.[Pubmed]
|
|
| Proteomic identification and characterization of a novel peroxisomal adenine nucleotide transporter supplying ATP for fatty acid beta-oxidation in soybean and Arabidopsis.[Pubmed]
|
|
| The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in DeltapH formation across peroxisomal membranes.[Pubmed]
|
|
| Identification of human PMP34 as a peroxisomal ATP transporter.[Pubmed]
|
|
| The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction.[Pubmed]
|
|
| Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter.[Pubmed]
|
|
| Developmental analysis of a putative ATP/ADP carrier protein localized on glyoxysomal membranes during the peroxisome transition in pumpkin cotyledons.[Pubmed]
|
|
| Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisomal membrane protein Pmp47 is essential in the metabolism of middle-chain fatty acid in yeast peroxisomes and Is associated with peroxisome proliferation.[Pubmed]
|
|
| Topogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34.[Pubmed]
|
|
| Identification and characterization of human PMP34, a protein closely related to the peroxisomal integral membrane protein PMP47 of Candida boidinii.[Pubmed]
|
|
| Multiple distinct targeting signals in integral peroxisomal membrane proteins.[Pubmed]
|
|
| MONODEHYROASCORBATE REDUCTASE4 is required for seed storage oil hydrolysis and postgerminative growth in Arabidopsis.[Pubmed]
|
|
| Arabidopsis peroxin 16 trafficks through the ER and an intermediate compartment to pre-existing peroxisomes via overlapping molecular targeting signals.[Pubmed]
|
|
| Senescence-specific regulation of catalases in Arabidopsis thaliana (L.) Heynh.[Pubmed]
|
|
| The Arabidopsis ascorbate peroxidase 3 is a peroxisomal membrane-bound antioxidant enzyme and is dispensable for Arabidopsis growth and development.[Pubmed]
|
|
| Arabidopsis peroxisomes possess functionally redundant membrane and matrix isoforms of monodehydroascorbate reductase.[Pubmed]
|
|
| Arabidopsis thaliana plants overexpressing thylakoidal ascorbate peroxidase show increased resistance to Paraquat-induced photooxidative stress and to nitric oxide-induced cell death.[Pubmed]
|
|
| Characterization of the targeting signal of the Arabidopsis 22-kD integral peroxisomal membrane protein.[Pubmed]
|
|
| Peroxisomal ascorbate peroxidase resides within a subdomain of rough endoplasmic reticulum in wild-type Arabidopsis cells.[Pubmed]
|
|
| Cloning of peroxisomal ascorbate peroxidase gene from barley and enhanced thermotolerance by overexpressing in Arabidopsis thaliana.[Pubmed]
|
|
| How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins.[Pubmed]
|
|
| Pumpkin peroxisomal ascorbate peroxidase is localized on peroxisomal membranes and unknown membranous structures.[Pubmed]
|
|
| Are diverse signalling pathways integrated in the regulation of arabidopsis antioxidant defence gene expression in response to excess excitation energy?[Pubmed]
|
|
| Overexpression of an Arabidopsis peroxisomal ascorbate peroxidase gene in tobacco increases protection against oxidative stress.[Pubmed]
|
|
| ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes.[Pubmed]
|
|
| Autophagy-related pathways and specific role of sterol glucoside in yeasts.[Pubmed]
|
|
| Atg26 is not involved in autophagy-related pathways in Saccharomyces cerevisiae.[Pubmed]
|
|
| Topogenesis of peroxisomal proteins does not require a functional cytoplasm-to-vacuole transport.[Pubmed]
|
|
| Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway.[Pubmed]
|
|
| Autophagy in yeast: a review of the molecular machinery.[Pubmed]
|
|
| Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris.[Pubmed]
|
|
| Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways.[Pubmed]
|
|
| Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole.[Pubmed]
|
|
| Structure and function of the yeast vacuole and its role in autophagy.[Pubmed]
|
|
| The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway.[Pubmed]
|
|
| Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway.[Pubmed]
|
|
| Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways.[Pubmed]
|
|
| Quantification and regulation of the subcellular distribution of bile acid coenzyme A:amino acid N-acyltransferase activity in rat liver.[Pubmed]
|
|
| Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: implications for intracellular bile salt transport.[Pubmed]
|
|
| Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts.[Pubmed]
|
|
| Plant catalase is imported into peroxisomes by Pex5p but is distinct from typical PTS1 import.[Pubmed]
|
|
| Conditional oxidative stress responses in the Arabidopsis photorespiratory mutant cat2 demonstrate that redox state is a key modulator of daylength-dependent gene expression, and define photoperiod as a crucial factor in the regulation of H2O2-induced cell death.[Pubmed]
|
|
| Significance of plant sulfite oxidase.[Pubmed]
|
|
| Identification and characterization of a stress-inducible and a constitutive small heat-shock protein targeted to the matrix of plant peroxisomes.[Pubmed]
|
|
| Plant sulfite oxidase as novel producer of H2O2: combination of enzyme catalysis with a subsequent non-enzymatic reaction step.[Pubmed]
|
|
| Catalase deficiency drastically affects gene expression induced by high light in Arabidopsis thaliana.[Pubmed]
|
|
| Identification of peroxisomal targeting signal of pumpkin catalase and the binding analysis with PTS1 receptor.[Pubmed]
|
|
| Distribution and characterization of peroxisomes in Arabidopsis by visualization with GFP: dynamic morphology and actin-dependent movement.[Pubmed]
|
|
| Hydrogen peroxide homeostasis: activation of plant catalase by calcium/calmodulin.[Pubmed]
|
|
| Integrated temporal regulation of the photorespiratory pathway. Circadian regulation of two Arabidopsis genes encoding serine hydroxymethyltransferase.[Pubmed]
|
|
| Psychosine-induced alterations in peroxisomes of twitcher mouse liver.[Pubmed]
|
|
| Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration.[Pubmed]
|
|
| Characterization and regulation of monocarboxylate cotransporters Slc16a7 and Slc16a3 in preimplantation mouse embryos.[Pubmed]
|
|
| Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.[Pubmed]
|
|
| Short- and medium-chain carnitine acyltransferases and acyl-CoA thioesterases in mouse provide complementary systems for transport of beta-oxidation products out of peroxisomes.[Pubmed]
|
|
| Peroxisomes in human and mouse testis: differential expression of peroxisomal proteins in germ cells and distinct somatic cell types of the testis.[Pubmed]
|
|
| Differential expression of peroxisomal matrix and membrane proteins during postnatal development of mouse brain.[Pubmed]
|
|
| Relationship between reactive oxygen species and heme metabolism during the differentiation of Neuro2a cells.[Pubmed]
|
|
| Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes.[Pubmed]
|
|
| Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction.[Pubmed]
|
|
| Human Mpv17-like protein is localized in peroxisomes and regulates expression of antioxidant enzymes.[Pubmed]
|
|
| Peroxisomal multifunctional protein-2 deficiency causes motor deficits and glial lesions in the adult central nervous system.[Pubmed]
|
|
| Functional domains and dynamic assembly of the peroxin Pex14p, the entry site of matrix proteins.[Pubmed]
|
|
| OCTN3 is a mammalian peroxisomal membrane carnitine transporter.[Pubmed]
|
|
| Extension of murine life span by overexpression of catalase targeted to mitochondria.[Pubmed]
|
|
| Overexpression of human acyl-CoA thioesterase upregulates peroxisome biogenesis.[Pubmed]
|
|
| Catalase transgenic mice: characterization and sensitivity to oxidative stress.[Pubmed]
|
|
| Involvement of the endoplasmic reticulum in peroxisome formation.[Pubmed]
|
|
| Mutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlation.[Pubmed]
|
|
| Cardiac-specific overexpression of catalase rescues ventricular myocytes from ethanol-induced cardiac contractile defect.[Pubmed]
|
|
| Molecular immunolabeling with recombinant single-chain variable fragment (scFv) antibodies designed with metal-binding domains.[Pubmed]
|
|
| Purification of brain peroxisomes and localization of 3-hydroxy-3-methylglutaryl coenzyme A reductase.[Pubmed]
|
|
| Suppressive effect of curcumin on trichloroethylene-induced oxidative stress.[Pubmed]
|
|
| Levels of DNA damage are unaltered in mice overexpressing human catalase in nuclei.[Pubmed]
|
|
| Cellular and subcellular localization of catalase in the heart of transgenic mice.[Pubmed]
|
|
| Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis.[Pubmed]
|
|
| Effects of vitamin A deficiency on selected xenobiotic-metabolizing enzymes and defenses against oxidative stress in mouse liver.[Pubmed]
|
|
| Hepatic histopathology of a vitamin A overdose in mouse liver.[Pubmed]
|
|
| Influence of dietary fat on the effect of endotoxin on murine hepatic peroxisomes.[Pubmed]
|
|
| Elevated catalase activity in red and white muscles of MyoD gene-inactivated mice.[Pubmed]
|
|
| Hepatotumorigenicity and peroxisome proliferation induced by the hypolipidemic CI-924 in a two-year study in male and female B6C3F1 mice.[Pubmed]
|
|
| Modification of lipoperoxidative effects of dichloroacetate and trichloroacetate is associated with peroxisome proliferation.[Pubmed]
|
|
| The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.[Pubmed]
|
|
| Effects of acetylsalicylic acid on parameters related to peroxisome proliferation in mouse liver.[Pubmed]
|
|
| X-linked dominant ichthyosis with peroxisomal deficiency. An ultrastructural and ultracytochemical study of the Conradi-Hünermann syndrome and its murine homologue, the bare patches mouse.[Pubmed]
|
|
| Comparison of the potencies of (+)- and (-)-2-ethylhexanoic acid in causing peroxisome proliferation and related biological effects in mouse liver.[Pubmed]
|
|
| Effects of clofibrate withdrawal on peroxisomes in mouse hepatocytes.[Pubmed]
|
|
| Peroxisomes in liver, kidney and duodenum of nude mice bearing xenografts of human pancreatic adenocarcinomas.[Pubmed]
|
|
| Peroxisomes and reactive oxygen species, a lasting challenge.[Pubmed]
|
|
| Integrated fluorescence and transmission electron microscopy.[Pubmed]
|
|
| Kinetics of hydrogen peroxide elimination by astrocytes and C6 glioma cells analysis based on a mathematical model.[Pubmed]
|
|
| Purification of a crude mitochondrial fraction by density-gradient centrifugation.[Pubmed]
|
|
| Role of peroxisomes in the swift increase in alcohol metabolism.[Pubmed]
|
|
| Loss of peroxisomes causes oxygen insensitivity of the histochemical assay of glucose-6-phosphate dehydrogenase activity to detect cancer cells.[Pubmed]
|
|
| Treatment of surgically induced acute liver failure by transplantation of HNF4-overexpressing embryonic stem cells.[Pubmed]
|
|
| The behavior of peroxisomes in vitro: mammalian peroxisomes are osmotically sensitive particles.[Pubmed]
|
|
| Detailed analytical subcellular fractionation of non-pregnant porcine corpus luteum reveals peroxisomes of normal size and significant UDP-glucuronosyltransferase activity in the high-speed supernatant.[Pubmed]
|
|
| Modified peroxisomes in primary hepatocyte cultures.[Pubmed]
|
|
| Regulation of peroxisomal genes by DHEA and vitamin D.[Pubmed]
|
|
| Effects of dibromoacetonitrile on rats following 13-week drinking water exposure.[Pubmed]
|
|
| A simple method of rat renal brush border membrane preparation using polyethylene glycol precipitation.[Pubmed]
|
|
| Expression of catalase mRNA and protein in adult rat brain: detection by nonradioactive in situ hybridization with signal amplification by catalyzed reporter deposition (ISH-CARD) and immunohistochemistry (IHC)/immunofluorescence (IF).[Pubmed]
|
|
| Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock.[Pubmed]
|
|
| Hepatocyte polarity and the peroxisomal compartment: a comparative study.[Pubmed]
|
|
| Damage to subcellular structures evoked by lipid peroxidation.[Pubmed]
|
|
| A novel pex2 mutant: catalase-deficient but temperature-sensitive PTS1 and PTS2 import.[Pubmed]
|
|
| A PEX6-defective peroxisomal biogenesis disorder with severe phenotype in an infant, versus mild phenotype resembling Usher syndrome in the affected parents.[Pubmed]
|
|
| Endogenous and endobiotic induced reactive oxygen species formation by isolated hepatocytes.[Pubmed]
|
|
| Catalase contents in cells determine sensitivity to the apoptosis inducer gallic acid.[Pubmed]
|
|
| Localization of cytosolic NADP-dependent isocitrate dehydrogenase in the peroxisomes of rat liver cells: biochemical and immunocytochemical studies.[Pubmed]
|
|
| Catalase immunocytochemistry allows automatic detection of lung type II alveolar cells.[Pubmed]
|
|
| Aging lowers steady-state antioxidant enzyme and stress protein expression in primary hepatocytes.[Pubmed]
|
|
| Peroxisomal proteins in rat gametes.[Pubmed]
|
|
| The role of 15-lipoxygenase in disruption of the peroxisomal membrane and in programmed degradation of peroxisomes in normal rat liver.[Pubmed]
|
|
| Oxidative stress, microsomal and peroxisomal fatty acid oxidation in the liver of rats treated with acetone.[Pubmed]
|
|
| Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes.[Pubmed]
|
|
| High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats.[Pubmed]
|
|
| Isolation and biochemical characterization of peroxisomes from cultured rat glial cells.[Pubmed]
|
|
| Disruption of the interaction of the longer isoform of Pex5p, Pex5pL, with Pex7p abolishes peroxisome targeting signal type 2 protein import in mammals. Study with a novel Pex5-impaired Chinese hamster ovary cell mutant.[Pubmed]
|
|
| Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures.[Pubmed]
|
|
| Endotoxin induces structure-function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators.[Pubmed]
|
|
| Current cytochemical techniques for the investigation of peroxisomes. A review.[Pubmed]
|
|
| Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells.[Pubmed]
|
|
| Differential binding of proteins to peroxisomes in rat hepatoma cells: unique association of enzymes involved in isoprenoid metabolism.[Pubmed]
|
|
| Newly identified Chinese hamster ovary cell mutants defective in peroxisome assembly represent complementation group A of human peroxisome biogenesis disorders and one novel group in mammals.[Pubmed]
|
|
| Maturation of the liver-specific peroxisome versus laminin, collagen IV and integrin expression.[Pubmed]
|
|
| 3-Hydroxy-3-methylglutaryl coenzyme A lyase: targeting and processing in peroxisomes and mitochondria.[Pubmed]
|
|
| Peroxisomes are involved in the swift increase in alcohol metabolism.[Pubmed]
|
|
| Some characteristics of peroxisomes in the slime mold, Dictyostelium discoideum.[Pubmed]
|
|
| The involvement of the plasma membrane in the development of Dictyostelium discoideum. I. Purification of the plasma membrane.[Pubmed]
|
|
| Dibutylphthalate and Tween 80 alter ultrastructure in Candida albicans: implications for peroxisome proliferation.[Pubmed]
|
|
| Catalase modifies yeast Saccharomyces cerevisiae response towards S-nitrosoglutathione-induced stress.[Pubmed]
|
|
| Sodium nitroprusside induces mild oxidative stress in Saccharomyces cerevisiae.[Pubmed]
|
|
| Catalases protect cellular proteins from oxidative modification in Saccharomyces cerevisiae.[Pubmed]
|
|
| Dual targeting of yeast catalase A to peroxisomes and mitochondria.[Pubmed]
|
|
| Overexpression of peroxisomal malate dehydrogenase MDH3 gene enhances cell death on H2O2 stress in the ald5 mutant of Saccharomyces cerevisiae.[Pubmed]
|
|
| Effect of yeast CTA1 gene expression on response of tobacco plants to tobacco mosaic virus infection.[Pubmed]
|
|
| Mouse very long-chain acyl-CoA synthetase in X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Synthesis of polyhydroxyalkanoate in the peroxisome of Saccharomyces cerevisiae by using intermediates of fatty acid beta-oxidation.[Pubmed]
|
|
| A mutation in the yeast mitochondrial ribosomal protein Rml2p is associated with a defect in catalase gene expression.[Pubmed]
|
|
| Overproduction of Pex5p stimulates import of alcohol oxidase and dihydroxyacetone synthase in a Hansenula polymorpha Pex14 null mutant.[Pubmed]
|
|
| Targeting and subcellular localization of Toxoplasma gondii catalase. Identification of peroxisomes in an apicomplexan parasite.[Pubmed]
|
|
| Identification and characterization of the human orthologue of yeast Pex14p.[Pubmed]
|
|
| Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: a sharp increase of the protein level induces the proliferation of numerous, small protein-import competent peroxisomes.[Pubmed]
|
|
| The Hansenula polymorpha PEX14 gene encodes a novel peroxisomal membrane protein essential for peroxisome biogenesis.[Pubmed]
|
|
| A branched pathway for peroxisomal protein import: S. cerevisiae ghosts and an intraperoxisomal PTS2 receptor.[Pubmed]
|
|
| Localization and targeting of isocitrate lyases in Saccharomyces cerevisiae.[Pubmed]
|
|
| Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor.[Pubmed]
|
|
| The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.[Pubmed]
|
|
| Targeting of human catalase to peroxisomes is dependent upon a novel COOH-terminal peroxisomal targeting sequence.[Pubmed]
|
|
| Pip2p: a transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae.[Pubmed]
|
|
| A C-terminal region of the Saccharomyces cerevisiae transcription factor ADR1 plays an important role in the regulation of peroxisome proliferation by fatty acids.[Pubmed]
|
|
| Expression of genes encoding peroxisomal proteins in Saccharomyces cerevisiae is regulated by different circuits of transcriptional control.[Pubmed]
|
|
| Novel peroxisome clustering mutants and peroxisome biogenesis mutants of Saccharomyces cerevisiae.[Pubmed]
|
|
| A Saccharomyces cerevisiae upstream activating sequence mediates induction of peroxisome proliferation by fatty acids.[Pubmed]
|
|
| Two independent peroxisomal targeting signals in catalase A of Saccharomyces cerevisiae.[Pubmed]
|
|
| Human catalase is imported and assembled in peroxisomes of Saccharomyces cerevisiae.[Pubmed]
|
|
| Inhibitory action of palmitic acid on the growth of Saccharomyces cerevisiae.[Pubmed]
|
|
| Isolation of peroxisome assembly mutants from Saccharomyces cerevisiae with different morphologies using a novel positive selection procedure.[Pubmed]
|
|
| Peroxisome biogenesis in Saccharomyces cerevisiae.[Pubmed]
|
|
| Control of peroxisome proliferation in Saccharomyces cerevisiae by ADR1, SNF1 (CAT1, CCR1) and SNF4 (CAT3).[Pubmed]
|
|
| Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells.[Pubmed]
|
|
| Vector-mediated overexpression of catalase A in the yeast Saccharomyces cerevisiae induces inclusion body formation.[Pubmed]
|
|
| The Saccharomyces cerevisiae ADR1 gene is a positive regulator of transcription of genes encoding peroxisomal proteins.[Pubmed]
|
|
| Association of glyoxylate and beta-oxidation enzymes with peroxisomes of Saccharomyces cerevisiae.[Pubmed]
|
|
| Fate of highly expressed proteins destined to peroxisomes in Saccharomyces cerevisiae.[Pubmed]
|
|
| Functional complementation of catalase-defective peroxisomes in a methylotrophic yeast by import of the catalase A from Saccharomyces cerevisiae.[Pubmed]
|
|
| Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae.[Pubmed]
|
|
| Functional expression and peroxisomal targeting of rat urate oxidase in monkey kidney cells.[Pubmed]
|
|
| Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity.[Pubmed]
|
|
| Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line.[Pubmed]
|
|
| Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme.[Pubmed]
|
|
| Cytochemical localization of a D-amino acid oxidizing enzyme in peroxisomes of Drosophila melanogaster.[Pubmed]
|
|
| Peroxisomes in wild-type and rosy mutant Drosophila melanogaster.[Pubmed]
|
|
| Studies by the National Toxicology Program on di(2-ethylhexyl)phthalate.[Pubmed]
|
|
| Effect of catalase-specific inhibitor 3-amino-1,2,4-triazole on yeast peroxisomal catalase in vivo.[Pubmed]
|
|
| Peroxisomal catalase in the methylotrophic yeast Candida boidinii: transport efficiency and metabolic significance.[Pubmed]
|
|
| Isolation, purification, and characterization of catalase from the methylotrophic yeast Pichia pastoris.[Pubmed]
|
|
| Antioxidant system within yeast peroxisome. Biochemical and physiological characterization of CbPmp20 in the methylotrophic yeast Candida boidinii.[Pubmed]
|
|
| Detection and substrate selectivity of new microbial D-amino acid oxidases.[Pubmed]
|
|
| Evaluation of peroxisomal heme in yeast.[Pubmed]
|
|
| The absence of Pmp47, a putative yeast peroxisomal transporter, causes a defect in transport and folding of a specific matrix enzyme.[Pubmed]
|
|
| Induction of peroxisome proliferation and increase of catalase activity in yeast, Candida albicans, by cadmium.[Pubmed]
|
|
| Beta-oxidation of butyrate, the short-chain-length fatty acid, occurs in peroxisomes in the yeast Candida tropicalis.[Pubmed]
|
|
| Development of multipurpose peroxisomes in Candida boidinii grown in oleic acid-methanol limited continuous cultures.[Pubmed]
|
|
| Effect of increasing methanol concentrations on physiology and cytology of Candida boidinii.[Pubmed]
|
|
| Evidence of peroxisomes and peroxisomal enzyme activities in the oleaginous yeast Apiotrichum curvatum.[Pubmed]
|
|
| Peroxisomal assembly: membrane proliferation precedes the induction of the abundant matrix proteins in the methylotrophic yeast Candida boidinii.[Pubmed]
|
|
| Lipid metabolism and cell composition of the oleaginous yeast Apiotrichum curvatum grown at different carbon to nitrogen ratios.[Pubmed]
|
|
| Proliferation and metabolic significance of peroxisomes in Candida boidinii during growth on D-alanine or oleic acid as the sole carbon source.[Pubmed]
|
|
| Enzyme activities in oleaginous yeasts accumulating and utilizing exogenous or endogenous lipids.[Pubmed]
|
|
| Production of Formaldehyde by Detergent-Treated Cells of a Methanol Yeast, Candida boidinii S2 Mutant Strain AOU-1.[Pubmed]
|
|
| Isolation of cDNA clones coding for peroxisomal proteins of Candida tropicalis: identification and sequence of a clone for catalase.[Pubmed]
|
|
| A proton-translocating adenosine triphosphatase is associated with the peroxisomal membrane of yeasts.[Pubmed]
|
|
| Properties of catalase purified from a methanol-grown yeast, Kloeckera sp. 2201.[Pubmed]
|
|
| Dihydroxyacetone synthase is an abundant constituent of the methanol-induced peroxisome of Candida boidinii.[Pubmed]
|
|
| Peroxisomal beta-oxidation system of Candida tropicalis. Purification of a multifunctional protein possessing enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase and 3-hydroxyacyl-CoA epimerase activities.[Pubmed]
|
|
| Biogenesis and metabolic significance of microbodies in urate-utilizing yeasts.[Pubmed]
|
|
| Significance of yeast peroxisomes in the metabolism of choline and ethanolamine.[Pubmed]
|
|
| Cell-free translation and regulation of Candida tropicalis catalase messenger RNA.[Pubmed]
|
|
| Properties of catalase purified from whole cells and peroxisomes of n-alkane-grown Candida tropicalis.[Pubmed]
|
|
| Peroxisomes of alkane-grown yeast: fundamental and practical aspects.[Pubmed]
|
|
| Development of amine oxidase-containing peroxisomes in yeasts during growth on glucose in the presence of methylamine as the sole source of nitrogen.[Pubmed]
|
|
| Localization of carnitine acetyltransferase in peroxisomes and in mitochondria of n-alkane-grown Candida tropicalis.[Pubmed]
|
|
| The effects of miconazole on the ultrastructure of Candida albicans.[Pubmed]
|
|
| Alcohol oxidase and catalase in peroxisomes of methanol-grown Candida boidinii.[Pubmed]
|
|
| Enzyme cytochemistry of Candida albicans.[Pubmed]
|
|
| Peroxisomal localization of D-aspartate oxidase and development of peroxisomes in the yeast Cryptococcus humicolus UJ1 grown on D-aspartate.[Pubmed]
|
|
| Lack of peroxisomal catalase causes a progeric phenotype in Caenorhabditis elegans.[Pubmed]
|
|
| Peroxisomes of the nematode Caenorhabditis elegans: distribution and morphological characteristics.[Pubmed]
|
|
| Immunological detection of alkaline-diaminobenzidine-negativeperoxisomes of the nematode Caenorhabditis elegans purification and unique pH optima of peroxisomal catalase.[Pubmed]
|
|
| Peroxisome biogenesis occurs in late dorsal-anterior structures in the development of Xenopus laevis.[Pubmed]
|
|
| Peroxisomes in pigment epithelium and Müller cells of amphibian retina possess D-amino acid oxidase as well as catalase.[Pubmed]
|
|
| Development of peroxisomes in amphibians. II. Cytochemical and biochemical studies on the liver, kidney, and pancreas.[Pubmed]
|
|
| Methods of plate pexophagy monitoring and positive selection for ATG gene cloning in yeasts.[Pubmed]
|
|
| The Yarrowia lipolytica gene PAY2 encodes a 42-kDa peroxisomal integral membrane protein essential for matrix protein import and peroxisome enlargement but not for peroxisome membrane proliferation.[Pubmed]
|
|
| Renal cell carcinoma and oxidative stress: The lack of peroxisomes.[Pubmed]
|
|
| Genotype-phenotype correlation in PEX5-deficient peroxisome biogenesis defective cell lines.[Pubmed]
|
|
| Progeric effects of catalase inactivation in human cells.[Pubmed]
|
|
| Restoration of peroxisomal catalase import in a model of human cellular aging.[Pubmed]
|
|
| Drug delivery to peroxisomes: employing unique trafficking mechanisms to target protein therapeutics.[Pubmed]
|
|
| A novel PEX12 mutation identified as the cause of a peroxisomal biogenesis disorder with mild clinical phenotype, mild biochemical abnormalities in fibroblasts and a mosaic catalase immunofluorescence pattern, even at 40 degrees C.[Pubmed]
|
|
| Peroxisomes and aging.[Pubmed]
|
|
| Hypocatalasemic fibroblasts accumulate hydrogen peroxide and display age-associated pathologies.[Pubmed]
|
|
| Use of the land snail Helix aspersa as sentinel organism for monitoring ecotoxicologic effects of urban pollution: an integrated approach.[Pubmed]
|
|
| Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue.[Pubmed]
|
|
| Catalase regulates cell growth in HL60 human promyelocytic cells: evidence for growth regulation by H(2)O(2).[Pubmed]
|
|
| Inhibition of peroxisomal functions due to oxidative imbalance induced by mistargeting of catalase to cytoplasm is restored by vitamin E treatment in skin fibroblasts from Zellweger syndrome-like patients.[Pubmed]
|
|
| A metabolic model describing the H2O2 elimination by mammalian cells including H2O2 permeation through cytoplasmic and peroxisomal membranes: comparison with experimental data.[Pubmed]
|
|
| Identification of the molecular defect in patients with peroxisomal mosaicism using a novel method involving culturing of cells at 40 degrees C: implications for other inborn errors of metabolism.[Pubmed]
|
|
| Reinvestigation of trihydroxycholestanoic acidemia reveals a peroxisome biogenesis disorder.[Pubmed]
|
|
| Overexpression of human peroxiredoxin 5 in subcellular compartments of Chinese hamster ovary cells: effects on cytotoxicity and DNA damage caused by peroxides.[Pubmed]
|
|
| Existence of catalase-less peroxisomes in Sf21 insect cells.[Pubmed]
|
|
| Peroxisome senescence in human fibroblasts.[Pubmed]
|
|
| A novel aberrant splicing mutation of the PEX16 gene in two patients with Zellweger syndrome.[Pubmed]
|
|
| Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.[Pubmed]
|
|
| In situ measurements of the pH of mammalian peroxisomes using the fluorescent protein pHluorin.[Pubmed]
|
|
| Peroxisomes in the apocrine sweat glands of the human axilla and their putative role in pheromone production.[Pubmed]
|
|
| Three-dimensional ultrastructural analysis of peroxisomes in HepG2 cells. Absence of peroxisomal reticulum but evidence of close spatial association with the endoplasmic reticulum.[Pubmed]
|
|
| Temperature sensitivity in peroxisome assembly processes characterizes milder forms of peroxisome biogenesis disorders.[Pubmed]
|
|
| Expression and prognostic significance of catalase in malignant mesothelioma.[Pubmed]
|
|
| Overexpression of wild-type and nuclear-targeted catalase modulates resistance to oxidative stress but does not alter spontaneous mutant frequencies at APRT.[Pubmed]
|
|
| Estimation of H2O2 gradients across biomembranes.[Pubmed]
|
|
| Rapid isolation and characterization of CHO mutants deficient in peroxisome biogenesis using the peroxisomal forms of fluorescent proteins.[Pubmed]
|
|
| Developmental and pathological expression of peroxisomal enzymes: their relationship of D-bifunctional protein deficiency and Zellweger syndrome.[Pubmed]
|
|
| Molecular mechanism of detectable catalase-containing particles, peroxisomes, in fibroblasts from a PEX2-defective patient.[Pubmed]
|
|
| L-Pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases.[Pubmed]
|
|
| Atypical refsum disease with pipecolic acidemia and abnormal catalase distribution.[Pubmed]
|
|
| Oxidation of human catalase by singlet oxygen in myeloid leukemia cells.[Pubmed]
|
|
| Defective PEX gene products correlate with the protein import, biochemical abnormalities, and phenotypic heterogeneity in peroxisome biogenesis disorders.[Pubmed]
|
|
| Overexpression of human catalase gene decreases oxidized lipid-induced cytotoxicity in vascular smooth muscle cells.[Pubmed]
|
|
| Disorders of peroxisome biogenesis: complementation analysis shows genetic heterogeneity with strong overrepresentation of one group (PEX1 deficiency).[Pubmed]
|
|
| Prenatal diagnosis of peroxisomal D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency.[Pubmed]
|
|
| Defective peroxisome biogenesis with a neuromuscular disorder resembling Werdnig-Hoffmann disease.[Pubmed]
|
|
| Restoration of PEX2 peroxisome assembly defects by overexpression of PMP70.[Pubmed]
|
|
| Immunocytochemical localization of L-alpha-hydroxyacid oxidase in dense bar of dumb-bell-shaped peroxisomes of monkey kidney.[Pubmed]
|
|
| Effects of clofibric and beclobric acid in rat and monkey hepatocyte primary culture: influence on peroxisomal and mitochondrial beta-oxidation and the activity of catalase, glutathione S-transferase and glutathione peroxidase.[Pubmed]
|
|
| Hepatic peroxisomal changes induced by a tetrazole-substituted alkoxyacetophenone in rats and comparison with other species.[Pubmed]
|
|
| Induction of fatty acid beta-oxidation and peroxisome proliferation in the liver of rhesus monkeys by DL-040, a new hypolipidemic agent.[Pubmed]
|
|
| Induction of hepatic peroxisome proliferation in nonrodent species, including primates.[Pubmed]
|
|
| Peroxisomes (microbodies) in the myocardium of rodents and primates. A comparative Ultrastructural cytochemical study.[Pubmed]
|
|
| Microperoxisomes in retinal pigment epithelium.[Pubmed]
|
|
| Fundamental contribution of beta-oxidation to polyketide mycotoxin production in planta.[Pubmed]
|
|
| Multiple catalase genes are differentially regulated in Aspergillus nidulans.[Pubmed]
|
|
| Characterization of oleate-nonutilizing mutants of Aspergillus nidulans isolated by the 3-amino-1,2,4-triazole positive selection method.[Pubmed]
|
|
| Expression of active spinach glycolate oxidase in Aspergillus nidulans.[Pubmed]
|
|
| A eukaryote without catalase-containing microbodies: Neurospora crassa exhibits a unique cellular distribution of its four catalases.[Pubmed]
|
|
| Hex-1, a gene unique to filamentous fungi, encodes the major protein of the Woronin body and functions as a plug for septal pores.[Pubmed]
|
|
| The function and specificity of the C-terminal tripeptide glyoxysomal targeting signal in Neurospora crassa.[Pubmed]
|
|
| Cytoplasmic organelles of trypanosomatids: a cytochemical and stereological study.[Pubmed]
|
|
| Host peroxisomal properties are not restored to normal after treatment of visceral leishmaniasis with sodium antimony gluconate.[Pubmed]
|
|
| Peroxisomal function is altered during leishmania infection.[Pubmed]
|
|
| Histopathologic analysis of hamster hepatocytes submitted to experimental infection with Leishmania donovani.[Pubmed]
|
|
| Cytochemical localization of peroxisomes in Tetrahymena pyriformis.[Pubmed]
|
|
| Synthesis of glycolytic and peroxisomal enzymes in Tetrahymena following a change in culture conditions.[Pubmed]
|
|
| Localization of some enzymes of beta-oxidation of fatty acids in the peroxisomes of Tetrahymena.[Pubmed]
|
|
| Peroxisomes and hydrogenosomes in protozoa.[Pubmed]
|
|
| Distribution of tricarboxylic acid cycle enzymes and glyoxylate cycle enzymes between mitochondria and peroxisomes in Tetrahymena pyriformis.[Pubmed]
|
|
| chy1, an Arabidopsis mutant with impaired beta-oxidation, is defective in a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase.[Pubmed]
|
|
| Subcellular targeting of nine calcium-dependent protein kinase isoforms from Arabidopsis.[Pubmed]
|
|
| Characterization of the induction of cytosolic and microsomal epoxide hydrolases by 2-ethylhexanoic acid in mouse liver.[Pubmed]
|
|
| The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14,643) on hepatic peroxisomes and peroxisome-associated enzymes.[Pubmed]
|
|
| Effects of oral administration of bezafibrate on peroxisomes and carnitine acetyltransferase in rat hepatocytes.[Pubmed]
|
|
| Peroxisomal fatty acid oxidation and inhibitors of the mitochondrial carnitine palmitoyltransferase I in isolated rat hepatocytes.[Pubmed]
|
|
| Purification of heart and liver mitochondrial carnitine acetyltransferase.[Pubmed]
|
|
| Induction of hepatic peroxisomes by a new, non-carboxylate-containing drug, bifonazole.[Pubmed]
|
|
| Response to thyroxine of lamellar bodies, peroxisomes and peroxisomal enzymes in the adult rat lung.[Pubmed]
|
|
| Effects of thia-substituted fatty acids on mitochondrial and peroxisomal beta-oxidation. Studies in vivo and in vitro.[Pubmed]
|
|
| Proliferation of peroxisomes without simultaneous induction of the peroxisomal fatty acid beta-oxidation.[Pubmed]
|
|
| Participation of peroxisomes in lipid biosynthesis in the harderian gland of guinea pig.[Pubmed]
|
|
| Rat liver metabolism of dicarboxylic acids.[Pubmed]
|
|
| Suppression of clofibrate-induced peroxisome proliferation in rat liver by nicardipine, a calcium antagonist.[Pubmed]
|
|
| Effects of prolonged administration of phthalate ester on the liver.[Pubmed]
|
|
| Valproic acid-induced increase in carnitine acetyltransferase in rat hepatocytes is not due to an induction of peroxisomes.[Pubmed]
|
|
| Di-n-octyl phthalate (DOP), a relatively ineffective peroxisome inducing straight chain isomer of the environmental contaminant di(2-ethylhexyl)phthalate (DEHP), enhances the development of putative preneoplastic lesions in rat liver.[Pubmed]
|
|
| Concentration-dependent inhibition of development of GGT positive foci in rat liver by the environmental contaminant di(2-ethylhexyl) phthalate.[Pubmed]
|
|
| Peroxisome-associated enzymes and serum lipids in tumour-bearing rats treated with peroxisome-proliferating agents.[Pubmed]
|
|
| Hypolipidemia and peroxisome proliferation induced by phenoxyacetic acid herbicides in rats.[Pubmed]
|
|
| Peroxisomal effects of phthalate esters in primary cultures of rat hepatocytes.[Pubmed]
|
|
| Carnitine acetyltransferase. Effect of malonyl-CoA, fasting and clofibrate feeding in mitochondria from different tissues.[Pubmed]
|
|
| Comparison of clofibrate and ethyl-5-(p-chlorophenoxy)-3-hydroxy-3-methylpentanoate induced changes in serum lipoprotein cholesterol and hepatic peroxisome proliferation in the normal rat.[Pubmed]
|
|
| Peroxisome proliferation in cultured rat hepatocytes produced by clofibrate and phthalate ester metabolites.[Pubmed]
|
|
| The short- and long-term effects of bezafibrate in the rat.[Pubmed]
|
|
| Effects of some hypolipidemic drugs on biochemical values and on hepatic peroxisomal enzymes of normolipemic rat.[Pubmed]
|
|
| Induction of peroxisomes and mitochondria by di(2-ethylhexyl)phthalate.[Pubmed]
|
|
| Physiological role of peroxisomal beta-oxidation in liver of fasted rats.[Pubmed]
|
|
| Effects of fat content in the diet on hepatic peroxisomes of the rat.[Pubmed]
|
|
| Carnitine acetyltransferase in developing mammals.[Pubmed]
|
|
| Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds.[Pubmed]
|
|
| Hepatic peroxisome proliferation: induction by BR-931, a hypolipidemic analog of WY-14,643.[Pubmed]
|
|
| Alterations in peroxisomes of hepatomas.[Pubmed]
|
|
| Enzymic and morphological studies on catalase positive particles from brown fat of cold adapted rats.[Pubmed]
|
|
| Comparison of the carnitine acyltransferase activites from rat liver peroxisomes and microsomes.[Pubmed]
|
|
| Effect of clofibrate application on morphology and enzyme content of liver peroxisomes.[Pubmed]
|
|
| Carnitine-dependent transport of acetyl coenzyme A in Candida albicans is essential for growth on nonfermentable carbon sources and contributes to biofilm formation.[Pubmed]
|
|
| Carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans.[Pubmed]
|
|
| Sorting of peroxisomal and mitochondrial carnitine acetyltransferase isozymes in the diploid yeast, Candida tropicalis.[Pubmed]
|
|
| Carnitine-dependent metabolic activities in Saccharomyces cerevisiae: three carnitine acetyltransferases are essential in a carnitine-dependent strain.[Pubmed]
|
|
| Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p.[Pubmed]
|
|
| Peroxisomal and mitochondrial carnitine acetyltransferase isozymes of the n-alkane-assimilating yeast, Candida tropicalis, occurred by alternative initiation of translation from the transcripts of a single gene.[Pubmed]
|
|
| Individual expression of Candida tropicalis peroxisomal and mitochondrial carnitine acetyltransferase-encoding genes and subcellular localization of the products in Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisomal and mitochondrial carnitine acetyltransferases of the n-alkane-assimilating yeast Candida Tropicalis. Analysis of gene structure and translation products.[Pubmed]
|
|
| Peroxisomal and mitochondrial carnitine acetyltransferases of Saccharomyces cerevisiae are encoded by a single gene.[Pubmed]
|
|
| Presence of carnitine acetyltransferase in peroxisomes and in mitochondria of oleic acid-grown Saccharomyces cerevisiae.[Pubmed]
|
|
| Candida albicans CTN gene family is induced during macrophage infection: homology, disruption and phenotypic analysis of CTN3 gene.[Pubmed]
|
|
| Changes in cell morphology and carnitine acetyltransferase activity in Candida albicans following growth on lipids and serum and after in vivo incubation in mice.[Pubmed]
|
|
| Enhancement of carnitine acetyltransferase synthesis in alkane-grown cells and propionate-grown cells of Candida tropicalis.[Pubmed]
|
|
| Peroxisomal and mitochondrial carnitine acetyltransferases in alkane-grown yeast Candida tropicalis.[Pubmed]
|
|
| Molecular cloning of cDNAs encoding human carnitine acetyltransferase and mapping of the corresponding gene to chromosome 9q34.1.[Pubmed]
|
|
| Modulation of metabolism in HepG2 cells upon treatment with cyclosporin A and Nva2-cyclosporin.[Pubmed]
|
|
| Carnitine--metabolism and functions.[Pubmed]
|
|
| Difference between species in response to a 3,5-dichloropyridyloxyphenoxy compound: induction of cytochrome P-450 and/or peroxisome proliferation.[Pubmed]
|
|
| The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase.[Pubmed]
|
|
| The effect of structurally divergent herbicides on mouse liver xenobiotic-metabolizing enzymes (P-450-dependent mono-oxygenases, epoxide hydrolases and glutathione S-transferases) and carnitine acetyltransferase.[Pubmed]
|
|
| Carnitine octanoyltransferase of mouse liver peroxisomes: properties and effect of hypolipidemic drugs.[Pubmed]
|
|
| Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse.[Pubmed]
|
|
| Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes.[Pubmed]
|
|
| Inhibition of carnitine acyltransferase activities by bile acids in rat liver peroxisomes.[Pubmed]
|
|
| Differences in the response of Sprague-Dawley and Lewis rats to bezafibrate: the hypolipidemic effect and the induction of peroxisomal enzymes.[Pubmed]
|
|
| Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver.[Pubmed]
|
|
| Characteristics of induction of peroxisomal fatty acid oxidation-related enzymes in rat liver by drugs. Relationships between structure and inducing activity.[Pubmed]
|
|
| Comparative induction of cytochrome P450IVA1 and peroxisome proliferation by ciprofibrate in the rat and marmoset.[Pubmed]
|
|
| Differential action of thyroid hormones and chemically related compounds on the activity of UDP-glucuronosyltransferases and cytochrome P-450 isozymes in rat liver.[Pubmed]
|
|
| Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation.[Pubmed]
|
|
| Structure-activity relationships for induction of peroxisomal enzyme activities by phthalate monoesters in primary rat hepatocyte cultures.[Pubmed]
|
|
| Proliferation of peroxisomes in pericentral hepatocytes of rat liver after administration of a new hypocholesterolemic agent (BM 15766). Sex-dependent ultrastructural differences.[Pubmed]
|
|
| Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate.[Pubmed]
|
|
| Hepatic peroxisome proliferation and hypolipidemic effects of di(2-ethylhexyl)phthalate in neonatal and adult rats.[Pubmed]
|
|
| Studies on the genetic effects of phthalic acid esters on cells in culture.[Pubmed]
|
|
| Effects of some anti-inflammatory drugs on biochemical values and on hepatic peroxisomal enzymes of rat.[Pubmed]
|
|
| Effect of the antilipolytic compound acipimox on peroxisome marker enzymes, lipid pattern and biotransformation related functions in rat liver.[Pubmed]
|
|
| Effects of long-term vitamin E deficiency and restoration on rat hepatic peroxisomes.[Pubmed]
|
|
| The effect of hypolipidaemic agents on peroxisomal beta-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation.[Pubmed]
|
|
| Comparative studies on di-(2-ethylhexyl) phthalate-induced hepatic peroxisome proliferation in the rat and hamster.[Pubmed]
|
|
| Induction of peroxisomal enzymes in livers of neonatal rats exposed to lactating mothers treated with hypolipidaemic drugs. Role of drug metabolite transfer in milk.[Pubmed]
|
|
| Changes in peroxisomal fatty acid oxidation in the diabetic rat liver.[Pubmed]
|
|
| Studies on peroxisomes. IX. Biochemical effects of simfibrate on precursor incorporation into polypeptide associated with peroxisome proliferation in rat liver.[Pubmed]
|
|
| Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta-oxidation of branched-chain fatty acids.[Pubmed]
|
|
| The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions.[Pubmed]
|
|
| Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids.[Pubmed]
|
|
| Developmental changes in carnitine octanoyltransferase gene expression in intestine and liver of suckling rats.[Pubmed]
|
|
| Natural trans-splicing in carnitine octanoyltransferase pre-mRNAs in rat liver.[Pubmed]
|
|
| Evidence of two catalytically active carnitine medium/long chain acyltransferases in rat liver peroxisomes.[Pubmed]
|
|
| Some properties of the malonyl-CoA sensitive carnitine long/medium chain acyltransferase activities of peroxisomes and microsomes of rat liver.[Pubmed]
|
|
| Cloning, sequencing, and regulation of rat liver carnitine octanoyltransferase: transcriptional stimulation of the enzyme during peroxisome proliferation.[Pubmed]
|
|
| Carnitine acyltransferase and acyl-coenzyme A hydrolase activities in human liver. Quantitative analysis of their subcellular localization.[Pubmed]
|
|
| Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.[Pubmed]
|
|
| Inhibition by etomoxir of rat liver carnitine octanoyltransferase is produced through the co-ordinate interaction with two histidine residues.[Pubmed]
|
|
| Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver.[Pubmed]
|
|
| Selective modulation of carnitine long-chain acyltransferase activities. Kinetics, inhibitors, and active sites of COT and CPT-II.[Pubmed]
|
|
| Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts.[Pubmed]
|
|
| Regulation of the long-chain carnitine acyltransferases.[Pubmed]
|
|
| Processing of carnitine octanoyltransferase pre-mRNAs by cis and trans-splicing.[Pubmed]
|
|
| Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination.[Pubmed]
|
|
| Proteomic analysis of the Arabidopsis cell wall reveals unexpected proteins with new cellular locations.[Pubmed]
|
|
| Oligomeric proteins containing N-terminal targeting signals are imported into peroxisomes in transgenic Arabidopsis.[Pubmed]
|
|
| Glyoxysomal malate dehydrogenase in pumpkin: cloning of a cDNA and functional analysis of its presequence.[Pubmed]
|
|
| Targeting and processing of a chimeric protein with the N-terminal presequence of the precursor to glyoxysomal citrate synthase.[Pubmed]
|
|
| Contribution of mitochondria and peroxisomes to palmitate oxidation in rat and bovine tissues.[Pubmed]
|
|
| The effect of dehydroepiandrosterone acetate on liver peroxisomal enzyme activities of male and female rats.[Pubmed]
|
|
| Glucagon and fasting do not activate peroxisomal fatty acid beta-oxidation in rat liver.[Pubmed]
|
|
| Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum.[Pubmed]
|
|
| Functional comparison of citrate synthase isoforms from S. cerevisiae.[Pubmed]
|
|
| Mutational and functional analysis of the cryptic N-terminal targeting signal for both mitochondria and peroxisomes in yeast peroxisomal citrate synthase Cit2p.[Pubmed]
|
|
| Mitochondrial transporters involved in oleic acid utilization and glutamate metabolism in yeast.[Pubmed]
|
|
| Identification of a cryptic N-terminal signal in Saccharomyces cerevisiae peroxisomal citrate synthase that functions in both peroxisomal and mitochondrial targeting.[Pubmed]
|
|
| Metabolic effects of mislocalized mitochondrial and peroxisomal citrate synthases in yeast Saccharomyces cerevisiae.[Pubmed]
|
|
| RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins.[Pubmed]
|
|
| RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.[Pubmed]
|
|
| Alternative topogenic signals in peroxisomal citrate synthase of Saccharomyces cerevisiae.[Pubmed]
|
|
| Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal.[Pubmed]
|
|
| Presence of a bacterial-like citrate synthase gene in Tetrahymena thermophila: recent lateral gene transfers (LGT) or multiple gene losses subsequent to a single ancient LGT?[Pubmed]
|
|
| Presence of D-amino-acid oxidase protein in mutant mice lacking D-amino-acid oxidase activity.[Pubmed]
|
|
| Peroxisome development in the metanephric kidney of mouse.[Pubmed]
|
|
| Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice.[Pubmed]
|
|
| D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.[Pubmed]
|
|
| Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat.[Pubmed]
|
|
| Immunocytochemical localization of D-amino acid oxidase in rat brain.[Pubmed]
|
|
| Presence of heterogeneous peroxisomal populations in the rat nervous tissue.[Pubmed]
|
|
| Immunohistochemical localization of peroxisomal enzymes in developing rat kidney tissues.[Pubmed]
|
|
| In situ heterogeneity of peroxisomal oxidase activities: an update.[Pubmed]
|
|
| Extinction coefficient of polymerized diaminobenzidine complexed with cobalt as final reaction product of histochemical oxidase reactions.[Pubmed]
|
|
| Effects of Di-(2-ethylhexyl)phthalate on peroxisomes of liver, kidney and brain of lactating rats and their pups.[Pubmed]
|
|
| Differentiation of kidney cortex peroxisomes in fetal and newborn rats.[Pubmed]
|
|
| Permeability properties of peroxisomes in digitonin-permeabilized rat hepatocytes. Evidence for free permeability towards a variety of substrates.[Pubmed]
|
|
| Peroxisomes and peroxisomal enzymes along the crypt-villus axis of the rat intestine.[Pubmed]
|
|
| In situ kinetic measurements of D-amino acid oxidase in rat liver with respect to its substrate specificity.[Pubmed]
|
|
| Peroxisome through cell differentiation and neoplasia.[Pubmed]
|
|
| Ultrastructural aspects of the biogenesis of peroxisomes in rat liver.[Pubmed]
|
|
| The use of unfixed cryostat sections for electron microscopic study of D-amino acid oxidase activity in rat liver.[Pubmed]
|
|
| Identification of pristanoyl-CoA oxidase as a distinct, clofibrate non-inducible enzyme in rat liver peroxisomes.[Pubmed]
|
|
| Frog cones as well as Müller cells have peroxisomes.[Pubmed]
|
|
| Postnatal development and isolation of peroxisomes from brain.[Pubmed]
|
|
| Peroxisomal oxidases and catalase in liver and kidney homogenates of normal and di(ethylhexyl)phthalate-fed rats.[Pubmed]
|
|
| Cytochemical and immunocytochemical study on the peroxisomes of rat liver after administration of a hypolipidemic drug, MLM-160.[Pubmed]
|
|
| D-aspartate oxidation by rat and bovine renal peroxisomes: an electron microscopic cytochemical study.[Pubmed]
|
|
| Altered acyl-CoA metabolism in riboflavin deficiency.[Pubmed]
|
|
| L-pipecolate oxidase: a distinct peroxisomal enzyme in man.[Pubmed]
|
|
| D-aspartate oxidase in rat, bovine and sheep kidney cortex is localized in peroxisomes.[Pubmed]
|
|
| Peroxisomal oxidases: cytochemical localization and biological relevance.[Pubmed]
|
|
| Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins.[Pubmed]
|
|
| Heterogenous staining of D-amino acid oxidase in peroxisomes of rat liver and kidney. A light and electron microscopic study.[Pubmed]
|
|
| Three-dimensional reconstruction of a peroxisomal reticulum in regenerating rat liver: evidence of interconnections between heterogeneous segments.[Pubmed]
|
|
| Immunoelectron microscopic localization of D-amino acid oxidase in rat kidney and liver.[Pubmed]
|
|
| Immunocytochemical localization of D-amino acid oxidase in the central clear matrix of rat kidney peroxisomes.[Pubmed]
|
|
| Effect of suloctidil on rat liver.[Pubmed]
|
|
| L-pipecolaturia in Zellweger syndrome.[Pubmed]
|
|
| Differentiation of liver peroxisomes in the foetal and newborn rat. Cytochemistry of catalase and D-aminoacid oxidase.[Pubmed]
|
|
| Effects of antilipolytic agents on rat liver peroxisomes and peroxisomal oxidative activities.[Pubmed]
|
|
| Kinetic properties of rat kidney D-amino acid oxidase associated with peroxisomes.[Pubmed]
|
|
| Rat liver peroxisomes. I. New peroxisome population induced by thyroid hormones in the liver of male rats.[Pubmed]
|
|
| Determination of the cross-points of rat liver peroxisomes, peroxisomal core and the core components by cross-partition.[Pubmed]
|
|
| Ultrastructural localization of D-amino acid oxidase in microperoxisomes of the rat nervous system.[Pubmed]
|
|
| Molecular cloning of TvDAO1, a gene encoding a D-amino acid oxidase from Trigonopsis variabilis and its expression in Saccharomyces cerevisiae and Kluyveromyces lactis.[Pubmed]
|
|
| Topography of very-long-chain-fatty-acid-activating activity in peroxisomes from rat liver.[Pubmed]
|
|
| Peroxisomal oxidation of thiazolidine carboxylates in firefly fat body, frog retina, and rat liver and kidney.[Pubmed]
|
|
| Peroxisomes in the head of Drosophila melanogaster.[Pubmed]
|
|
| Physiological role of the D-amino acid oxidase gene, DAO1, in carbon and nitrogen metabolism in the methylotrophic yeast Candida boidinii.[Pubmed]
|
|
| Peroxisomes induced in Candida boidinii by methanol, oleic acid and D-alanine vary in metabolic function but share common integral membrane proteins.[Pubmed]
|
|
| The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases.[Pubmed]
|
|
| Contributions of the immunogold technique to investigation of the biology of peroxisomes.[Pubmed]
|
|
| Peroxisomes and peroxisomal enzymes in the human fetal small intestine.[Pubmed]
|
|
| Histochemistry of peroxisomal enzyme activities: a tool in the diagnosis of Zellweger syndrome.[Pubmed]
|
|
| Molecular cloning and chromosomal localization of a human gene encoding D-amino-acid oxidase.[Pubmed]
|
|
| Multiple peroxisomal enzymatic deficiency disorders. A comparative biochemical and morphologic study of Zellweger cerebrohepatorenal syndrome and neonatal adrenoleukodystrophy.[Pubmed]
|
|
| Pseudo-Zellweger syndrome: deficiencies in several peroxisomal oxidative activities.[Pubmed]
|
|
| Zellweger syndrome: biochemical and morphological studies on two patients treated with clofibrate.[Pubmed]
|
|
| Activity of peroxisomal enzymes and intracellular distribution of catalase in Zellweger syndrome.[Pubmed]
|
|
| Peroxisomes (microbodies) in human glial tumors. a cytochemical ultrastructural study.[Pubmed]
|
|
| C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signal.[Pubmed]
|
|
| Cellular and subcellular distribution of D-aspartate oxidase in human and rat brain.[Pubmed]
|
|
| D-aspartate oxidase, a peroxisomal enzyme in liver of rat and man.[Pubmed]
|
|
| A 27.368 kDa retinal reductase in New Zealand white rabbit liver cytosol encoded by the peroxisomal retinol dehydrogenase-reductase cDNA: purification and characterization of the enzyme.[Pubmed]
|
|
| An outer segment localization signal at the C terminus of the photoreceptor-specific retinol dehydrogenase.[Pubmed]
|
|
| Binary structure of the two-domain (3R)-hydroxyacyl-CoA dehydrogenase from rat peroxisomal multifunctional enzyme type 2 at 2.38 A resolution.[Pubmed]
|
|
| Yeast peroxisomal multifunctional enzyme: (3R)-hydroxyacyl-CoA dehydrogenase domains A and B are required for optimal growth on oleic acid.[Pubmed]
|
|
| Substrate specificities of peroxisomal members of short-chain alcohol dehydrogenase superfamily: expression and characterization of dehydrogenase part of Candida tropicalis multifunctional enzyme.[Pubmed]
|
|
| The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import.[Pubmed]
|
|
| Peroxisome elongation and constriction but not fission can occur independently of dynamin-like protein 1.[Pubmed]
|
|
| Dynamin-like protein-dependent formation of Woronin bodies in Saccharomyces cerevisiae upon heterologous expression of a single protein.[Pubmed]
|
|
| The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.[Pubmed]
|
|
| Assay and functional analysis of dynamin-like protein 1 in peroxisome division.[Pubmed]
|
|
| The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11.[Pubmed]
|
|
| A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae.[Pubmed]
|
|
| A lethal defect of mitochondrial and peroxisomal fission.[Pubmed]
|
|
| Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis.[Pubmed]
|
|
| Elongation of peroxisomes as an indicator for efficient dynamin-like protein 1 knock down in mammalian cells.[Pubmed]
|
|
| The 3-hydroxyacyl-CoA epimerase activity of rat liver peroxisomes is due to the combined actions of two enoyl-CoA hydratases: a revision of the epimerase-dependent pathway of unsaturated fatty acid oxidation.[Pubmed]
|
|
| Evidence for a novel pathway for the targeting of a Saccharomyces cerevisiae peroxisomal protein belonging to the isomerase/hydratase family.[Pubmed]
|
|
| Peroxisomal beta-oxidation enzymes.[Pubmed]
|
|
| Sensitive analysis of serum 3alpha, 7alpha, 12alpha,24-tetrahydroxy- 5beta-cholestan-26-oic acid diastereomers using gas chromatography-mass spectrometry and its application in peroxisomal D-bifunctional protein deficiency.[Pubmed]
|
|
| Studies on the intracellular distributions of soluble epoxide hydrolase and of catalase by digitonin-permeabilization of hepatocytes isolated from control and clofibrate-treated mice.[Pubmed]
|
|
| Purification and characterization of an epoxide hydrolase from the peroxisomal fraction of mouse liver.[Pubmed]
|
|
| In vitro translation of cytosolic and peroxisomal epoxide hydrolase and catalase on liver polyribosomes from untreated and clofibrate-treated C57B1/6 mice.[Pubmed]
|
|
| Distribution and nature of epoxide hydrolase activity in subcellular organelles of mouse liver.[Pubmed]
|
|
| Subcellular localization of epoxide hydrolase in mouse liver and kidney.[Pubmed]
|
|
| Epoxide hydrolase activity in isolated peroxisomes of mouse liver.[Pubmed]
|
|
| An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase.[Pubmed]
|
|
| Microsomal and cytosolic epoxide hydrolases, the peroxisomal fatty acid beta-oxidation system and catalase. Activities, distribution and induction in rat liver parenchymal and non-parenchymal cells.[Pubmed]
|
|
| Induction of xenobiotic-metabolizing enzymes and peroxisome proliferation in rat liver caused by dietary exposure to di(2-ethylhexyl)phosphate.[Pubmed]
|
|
| Rat cytosolic epoxide hydrolase.[Pubmed]
|
|
| Immuno-electron-microscopic studies on the subcellular distribution of rat liver epoxide hydrolase and the effect of phenobarbitone and 2-acetamidofluorene treatment.[Pubmed]
|
|
| Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase.[Pubmed]
|
|
| Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins.[Pubmed]
|
|
| Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella.[Pubmed]
|
|
| Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana.[Pubmed]
|
|
| Characterization of Arabidopsis fluoroacetate-resistant mutants reveals the principal mechanism of acetate activation for entry into the glyoxylate cycle.[Pubmed]
|
|
| Two long-chain acyl-CoA synthetases from Arabidopsis thaliana involved in peroxisomal fatty acid beta-oxidation.[Pubmed]
|
|
| Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts.[Pubmed]
|
|
| X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases.[Pubmed]
|
|
| Very-long-chain fatty acid metabolism in adrenoleukodystrophy protein-deficient mice.[Pubmed]
|
|
| Hepatic enzymatic synthesis and hydrolysis of CoA esters of solvent-derived oxa acids.[Pubmed]
|
|
| Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism.[Pubmed]
|
|
| Phytanic acid activation in rat liver peroxisomes is catalyzed by long-chain acyl-CoA synthetase.[Pubmed]
|
|
| Paradoxical increase in peroxisomal cyanide-insensitive respiration following dietary exposure to WY-14,643 in the perfused liver.[Pubmed]
|
|
| Purification and properties of rat liver peroxisomal very-long-chain acyl-CoA synthetase.[Pubmed]
|
|
| Peroxisomal beta-oxidation of branched chain fatty acids in rat liver. Evidence that carnitine palmitoyltransferase I prevents transport of branched chain fatty acids into mitochondria.[Pubmed]
|
|
| Influence of chronic administration of valproate on ultrastructure and enzyme content of peroxisomes in rat liver and kidney. Oxidation of valproate by liver peroxisomes.[Pubmed]
|
|
| Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain.[Pubmed]
|
|
| Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids.[Pubmed]
|
|
| Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders.[Pubmed]
|
|
| Integral membrane polypeptides of rat liver peroxisomes: topology and response to different metabolic states.[Pubmed]
|
|
| Identity of long-chain acyl-coenzyme A synthetase of microsomes, mitochondria, and peroxisomes in rat liver.[Pubmed]
|
|
| Participation of peroxisomal beta-oxidation system in the chain-shortening of a xenobiotic acyl compound.[Pubmed]
|
|
| Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments.[Pubmed]
|
|
| Acyl-Coenzyme A synthetase and fatty acid oxidation in rat liver peroxisomes.[Pubmed]
|
|
| Intracellular Localization of Enzymes of Fatty Acid-beta-Oxidation in the Alga Cyanidium caldarium.[Pubmed]
|
|
| Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase.[Pubmed]
|
|
| A very long-chain acyl-CoA synthetase-deficient mouse and its relevance to X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Disruption of a yeast very-long-chain acyl-CoA synthetase gene simulates the cellular phenotype of X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy.[Pubmed]
|
|
| Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein.[Pubmed]
|
|
| Disruption of the Saccharomyces cerevisiae FAT1 gene decreases very long-chain fatty acyl-CoA synthetase activity and elevates intracellular very long-chain fatty acid concentrations.[Pubmed]
|
|
| Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system.[Pubmed]
|
|
| Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase.[Pubmed]
|
|
| Long-chain fatty Acyl-CoA synthetase enzymatic activity in rat liver cell nuclei.[Pubmed]
|
|
| Peroxisomal activation of long- and very long-chain fatty acids in the yeast Pichia pastoris.[Pubmed]
|
|
| Phytanic acid must be activated to phytanoyl-CoA prior to its alpha-oxidation in rat liver peroxisomes.[Pubmed]
|
|
| Subcellular distribution and characteristics of ciprofibroyl-CoA synthetase in rat liver. Its possible identity with long-chain acyl-CoA synthetase.[Pubmed]
|
|
| Characteristics and subcellular localization of pristanoyl-CoA synthetase in rat liver.[Pubmed]
|
|
| Long-chain-acyl-CoA synthetase and very-long-chain-acyl-CoA synthetase activities in peroxisomes and microsomes from rat liver. An enzymological study.[Pubmed]
|
|
| Evidence that peroxisomal acyl-CoA synthetase is located at the cytoplasmic side of the peroxisomal membrane.[Pubmed]
|
|
| Triacylglycerol synthesis in the oleaginous yeast Candida curvata D.[Pubmed]
|
|
| Subcellular localization of long-chain alcohol dehydrogenase and aldehyde dehydrogenase in n-alkane-grown Candida tropicalis.[Pubmed]
|
|
| Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.[Pubmed]
|
|
| Cerebral inflammation in X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Peroxisomal beta-oxidation of branched chain fatty acids in human skin fibroblasts.[Pubmed]
|
|
| X-linked adrenoleukodystrophy: identification of the primary defect at the level of a deficient peroxisomal very long chain fatty acyl-CoA synthetase using a newly developed method for the isolation of peroxisomes from skin fibroblasts.[Pubmed]
|
|
| Very long chain fatty acid beta-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts.[Pubmed]
|
|
| Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts.[Pubmed]
|
|
| Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.[Pubmed]
|
|
| Plant-like traits associated with metabolism of Trypanosoma parasites.[Pubmed]
|
|
| Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.[Pubmed]
|
|
| Import of fructose bisphosphate aldolase into the glycosomes of Trypanosoma brucei.[Pubmed]
|
|
| Interaction of Leishmania PTS2 receptor peroxin 7 with the glycosomal protein import machinery.[Pubmed]
|
|
| Cloning and characterization of Leishmania mexicana fructose-1,6-bisphosphate aldolase.[Pubmed]
|
|
| Nematode biochemistry. XIII. Peroxisomes in the free-living nematode, Turbatrix aceti.[Pubmed]
|
|
| Cytochemical changes in hepatocytes of rats with endotoxemia or sepsis: localization of fibronectin, calcium, and enzymes.[Pubmed]
|
|
| Succinate secreted by Trypanosoma brucei is produced by a novel and unique glycosomal enzyme, NADH-dependent fumarate reductase.[Pubmed]
|
|
| A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.[Pubmed]
|
|
| The crystal structure of glucose-6-phosphate isomerase from Leishmania mexicana reveals novel active site features.[Pubmed]
|
|
| Detection of mRNAs encoding peroxisomal proteins by non-radioactive in situ hybridization with digoxigenin-labelled cRNAs.[Pubmed]
|
|
| L-lactate dehydrogenase A4- and A3B isoforms are bona fide peroxisomal enzymes in rat liver. Evidence for involvement in intraperoxisomal NADH reoxidation.[Pubmed]
|
|
| Tomato bushy stunt virus co-opts the RNA-binding function of a host metabolic enzyme for viral genomic RNA synthesis.[Pubmed]
|
|
| Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis.[Pubmed]
|
|
| Purification and Characterization of Hydroxypyruvate Reductase from Cucumber Cotyledons.[Pubmed]
|
|
| Glyoxylate aminotransferase in peroxisomes from rat liver and kidney.[Pubmed]
|
|
| Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity.[Pubmed]
|
|
| Peroxisomal localization of glucose-6-phosphate dehydrogenase and pyrophosphate-stimulated dihydroxyacetone-phosphate acyltransferase in mouse kidney.[Pubmed]
|
|
| Predominant localization of dihydroxyacetone-phosphate acyltransferase activity in renal peroxisomes of male and female mice.[Pubmed]
|
|
| Acyl-CoA:dihydroxyacetone phosphate acyltransferase in human skin fibroblasts: study of its properties using a new assay method.[Pubmed]
|
|
| Comparison of the activities of some peroxisomal and extraperoxisomal lipid-metabolizing enzymes in liver and extrahepatic tissues of the rat.[Pubmed]
|
|
| Glycerolipid synthetic capacity of rat liver peroxisomes.[Pubmed]
|
|
| Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.[Pubmed]
|
|
| Subcellular localization of acyl coenzyme A: dihydroxyacetone phosphate acyltransferase in rat liver peroxisomes (microbodies).[Pubmed]
|
|
| Leishmania major expresses a single dihydroxyacetone phosphate acyltransferase localized in the glycosome, important for rapid growth and survival at high cell density and essential for virulence.[Pubmed]
|
|
| Rhizomelic chondrodysplasia punctata is caused by deficiency of human PEX7, a homologue of the yeast PTS2 receptor.[Pubmed]
|
|
| Etherphospholipid biosynthesis and dihydroxyactetone-phosphate acyltransferase: resolution of the genomic organization of the human gnpat gene and its use in the identification of novel mutations.[Pubmed]
|
|
| Zellweger syndrome in Saudi Arabia and its distinct features.[Pubmed]
|
|
| Isolation of a Chinese hamster fibroblast variant defective in dihydroxyacetonephosphate acyltransferase activity and plasmalogen biosynthesis: use of a novel two-step selection protocol.[Pubmed]
|
|
| Late-onset generalized disorder of peroxisomes.[Pubmed]
|
|
| Measurement of dihydroxyacetone-phosphate acyltransferase (DHAPAT) in chorionic villous samples, blood cells and cultured cells.[Pubmed]
|
|
| Peroxisomal abnormality in fibroblasts from involved skin of CHILD syndrome. Case study and review of peroxisomal disorders in relation to skin disease.[Pubmed]
|
|
| Transformation and characterization of mutant human fibroblasts defective in peroxisome assembly.[Pubmed]
|
|
| HMG-CoA reductase inhibitors perturb fatty acid metabolism and induce peroxisomes in keratinocytes.[Pubmed]
|
|
| Zellweger syndrome in a preterm, small for gestational age infant.[Pubmed]
|
|
| Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes.[Pubmed]
|
|
| Factors influencing the latency of the peroxisomal enzyme dihydroxyacetone-phosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts.[Pubmed]
|
|
| Acyl-CoA oxidase, peroxisomal thiolase and dihydroxyacetone phosphate acyltransferase: aberrant subcellular localization in Zellweger syndrome.[Pubmed]
|
|
| Congenital rubella syndrome associated with calcific epiphyseal stippling and peroxisomal dysfunction.[Pubmed]
|
|
| Zellweger-like syndrome with detectable hepatic peroxisomes: a variant form of peroxisomal disorder.[Pubmed]
|
|
| A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy).[Pubmed]
|
|
| A sibship with a mild variant of Zellweger syndrome.[Pubmed]
|
|
| Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment.[Pubmed]
|
|
| Zellweger syndrome: diagnostic assays, syndrome delineation, and potential therapy.[Pubmed]
|
|
| A prenatal test for the cerebro-hepato-renal (Zellweger) syndrome by demonstration of the absence of catalase-containing particles (peroxisomes) in cultured amniotic fluid cells.[Pubmed]
|
|
| A milder variant of Zellweger syndrome.[Pubmed]
|
|
| Targeted disruption of ether lipid synthesis in mice.[Pubmed]
|
|
| Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes.[Pubmed]
|
|
| Class F Thy-1-negative murine lymphoma cells are deficient in ether lipid biosynthesis.[Pubmed]
|
|
| Lipid biosynthesis in peroxisomes.[Pubmed]
|
|
| Biosynthesis of glycerolipid precursors in rat liver peroxisomes and their transport and conversion to phosphatidate in the endoplasmic reticulum.[Pubmed]
|
|
| Latency of the peroxisomal enzyme acyl-CoA:dihydroxyacetonephosphate acyltransferase in digitonin-permeabilized fibroblasts: the effect of ATP and ATPase inhibitors.[Pubmed]
|
|
| Changes in the activities of dihydroxyacetone phosphate and glycerol-3-phosphate acyltransferases in rat liver under various conditions.[Pubmed]
|
|
| A rapid method for the isolation of peroxisomes from rat liver.[Pubmed]
|
|
| Biochemical markers predicting survival in peroxisome biogenesis disorders.[Pubmed]
|
|
| Biochemical markers predicting survival in peroxisome biogenesis disorders.[Pubmed]
|
|
| A common PEX1 frameshift mutation in patients with disorders of peroxisome biogenesis correlates with the severe Zellweger syndrome phenotype.[Pubmed]
|
|
| Ether lipid biosynthesis: isolation and molecular characterization of human dihydroxyacetonephosphate acyltransferase.[Pubmed]
|
|
| Isolated dihydroxyacetonephosphate-acyl-transferase deficiency in rhizomelic chondrodysplasia punctata: clinical presentation, metabolic and histological findings.[Pubmed]
|
|
| Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients.[Pubmed]
|
|
| Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group.[Pubmed]
|
|
| Identification of pristanoyl-CoA oxidase activity in human liver and its deficiency in the Zellweger syndrome.[Pubmed]
|
|
| Infantile phytanic acid storage disease, a disorder of peroxisome biogenesis: a case report.[Pubmed]
|
|
| Chinese hamster ovary cell mutants defective in peroxisome biogenesis. Comparison to Zellweger syndrome.[Pubmed]
|
|
| Identification of L-pipecolate oxidase in human liver and its deficiency in the Zellweger syndrome.[Pubmed]
|
|
| Genetic heterogeneity in the cerebrohepatorenal (Zellweger) syndrome and other inherited disorders with a generalized impairment of peroxisomal functions. A study using complementation analysis.[Pubmed]
|
|
| Peroxisomes and peroxisomal functions in hyperpipecolic acidaemia.[Pubmed]
|
|
| Deficiency of enzymes catalyzing the biosynthesis of glycerol-ether lipids in Zellweger syndrome. A new category of metabolic disease involving the absence of peroxisomes.[Pubmed]
|
|
| Arabidopsis mutants define an in vivo role for isoenzymes of aspartate aminotransferase in plant nitrogen assimilation.[Pubmed]
|
|
| Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae.[Pubmed]
|
|
| The noninvolvement of MDH as NAD-oxidoreductase shuttle in rat liver peroxisomes.[Pubmed]
|
|
| Postnatal development of peroxisomal and mitochondrial enzymes in rat liver.[Pubmed]
|
|
| Molecular characterization of glycosomal NAD(+)-dependent glycerol 3-phosphate dehydrogenase from Trypanosoma brucei rhodesiense.[Pubmed]
|
|
| Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10.[Pubmed]
|
|
| Chloroplast unusual positioning1 is essential for proper chloroplast positioning.[Pubmed]
|
|
| Rapid hepatocyte nuclear translocation of the Forkhead Box M1B (FoxM1B) transcription factor caused a transient increase in size of regenerating transgenic hepatocytes.[Pubmed]
|
|
| Insights into the membrane proteome of rat liver peroxisomes: microsomal glutathione-S-transferase is shared by both subcellular compartments.[Pubmed]
|
|
| Principal component analysis of mass spectra of peptides generated from the tryptic digestion of protein mixtures.[Pubmed]
|
|
| The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.[Pubmed]
|
|
| Juxtaposition of peroxisomes and chromosomes in mitotic hepatocytes following methyl clofenapate administration to rats.[Pubmed]
|
|
| Characterizations of and interactions between bile ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis induced by ethionine.[Pubmed]
|
|
| Subcellular distribution of N-ethylmaleimide-stimulatable glutathione S-transferase activity in rat liver. Evidence of localization of glutathione S-transferase in peroxisomal membrane.[Pubmed]
|
|
| Quantitative stereological evaluation of four histochemical markers of altered foci in multistage hepatocarcinogenesis in the rat.[Pubmed]
|
|
| Identifying Pex21p as a protein that specifically interacts with yeast seryl-tRNA synthetase.[Pubmed]
|
|
| The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisomal targeting of mammalian hydroxyacid oxidase 1 requires the C-terminal tripeptide SKI.[Pubmed]
|
|
| Oxidative stress-mediated down-regulation of rat hydroxyacid oxidase 1, a liver-specific peroxisomal enzyme.[Pubmed]
|
|
| Immunoelectron microscopic localization of the isozymes of L-alpha-hydroxyacid oxidase in renal peroxisomes of beef and sheep: evidence of distinct intraorganellar subcompartmentation.[Pubmed]
|
|
| Electron microscopic cytochemical localization of alpha-hydroxyacid oxidase in rat kidney cortex. Heterogeneous staining of peroxisomes.[Pubmed]
|
|
| Electron microscopic cytochemical localization of alpha-hydroxyacid oxidase in rat liver. Association with the crystalline core and matrix of peroxisomes.[Pubmed]
|
|
| Light and electron microscopic localization of L-alpha-hydroxyacid oxidase in rat kidney revealed by immunocytochemical techniques.[Pubmed]
|
|
| Influence of subtotal hepatectomy on peroxisomes and peroxisomal enzymes of rat liver and isolated liver cell fractions.[Pubmed]
|
|
| Low-density particles (W-particles) containing catalase in Zellweger syndrome and normal fibroblasts.[Pubmed]
|
|
| Effect of x-irradiation on the permeability of L-alpha hydroxy acid oxidase from mouse liver peroxisomes.[Pubmed]
|
|
| Selective induction of peroxisomal enzymes by the hypolipidemic drug bezafibrate. Detection of modulations by automatic image analysis in conjunction with immunoelectron microscopy and immunoblotting.[Pubmed]
|
|
| Catalase in guinea pig hepatocytes is localized in cytoplasm, nuclear matrix and peroxisomes.[Pubmed]
|
|
| Cytochemical localization of catalase and several hydrogen peroxide-producing oxidases in the nucleoids and matrix of rat liver peroxisomes.[Pubmed]
|
|
| Unusual responses of rat hepatic and renal peroxisomes to RMI 14, 514, a new hypolipidemic agent.[Pubmed]
|
|
| Studies on peroxisomes. VI. Relationship between the peroxisomal core and urate oxidase.[Pubmed]
|
|
| Structure, composition, physical properties, and turnover of proliferated peroxisomes. A study of the trophic effects of Su-13437 on rat liver.[Pubmed]
|
|
| Studies on peroxisomes. V. Effect of ethyl p-chlorophenoxyisobutyrate on the centrifugal behavior of rat liver peroxisomes.[Pubmed]
|
|
| Ultrastructural localization of L-alpha-hydroxy acid oxidase in rat liver perioxisomes.[Pubmed]
|
|
| Cytochemical localization by ferricyanide reduction of -hydroxy acid oxidase activity in peroxisomes of rat kidney.[Pubmed]
|
|
| Mevalonate pyrophosphate decarboxylase is predominantly located in the cytosol of rat hepatocytes.[Pubmed]
|
|
| Molecular and biochemical characterization of hexokinase from Trypanosoma cruzi.[Pubmed]
|
|
| Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans.[Pubmed]
|
|
| Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp.[Pubmed]
|
|
| The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes.[Pubmed]
|
|
| Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies.[Pubmed]
|
|
| Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei.[Pubmed]
|
|
| Probing the role of compartmentation of glycolysis in procyclic form Trypanosoma brucei: RNA interference studies of PEX14, hexokinase, and phosphofructokinase.[Pubmed]
|
|
| Molecular characterization of the hexokinase gene from Leishmania major.[Pubmed]
|
|
| 3-Hydroxy-3-methylglutaryl-CoA lyase is present in mouse and human liver peroxisomes.[Pubmed]
|
|
| Investigation of the oligomeric status of the peroxisomal isoform of human 3-hydroxy-3-methylglutaryl-CoA lyase.[Pubmed]
|
|
| Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes.[Pubmed]
|
|
| Phytanic acid alpha-oxidation: identification of 2-hydroxyphytanoyl-CoA lyase in rat liver and its localisation in peroxisomes.[Pubmed]
|
|
| Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids.[Pubmed]
|
|
| The role of 2-hydroxyacyl-CoA lyase, a thiamin pyrophosphate-dependent enzyme, in the peroxisomal metabolism of 3-methyl-branched fatty acids and 2-hydroxy straight-chain fatty acids.[Pubmed]
|
|
| Phytanic acid alpha-oxidation in man: identification of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal enzyme with normal activity in Zellweger syndrome.[Pubmed]
|
|
| A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis.[Pubmed]
|
|
| Peroxisomal malate dehydrogenase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release.[Pubmed]
|
|
| A leaf-peroxisomal protein, hydroxypyruvate reductase, is produced by light-regulated alternative splicing.[Pubmed]
|
|
| Light regulates alternative splicing of hydroxypyruvate reductase in pumpkin.[Pubmed]
|
|
| Hydroxypyruvate reductase with a carboxy-terminal targeting signal to microbodies is expressed in Arabidopsis.[Pubmed]
|
|
| Plants express a lipid transfer protein with high similarity to mammalian sterol carrier protein-2.[Pubmed]
|
|
| Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance.[Pubmed]
|
|
| Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids.[Pubmed]
|
|
| MFE1, a member of the peroxisomal hydroxyacyl coenzyme A dehydrogenase family, affects fatty acid metabolism necessary for morphogenesis in Dictyostelium spp.[Pubmed]
|
|
| A novel HPLC-based method to diagnose peroxisomal D-bifunctional protein enoyl-CoA hydratase deficiency.[Pubmed]
|
|
| Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method.[Pubmed]
|
|
| Enoyl-CoA hydratase deficiency: identification of a new type of D-bifunctional protein deficiency.[Pubmed]
|
|
| Role of an ancestral d-bifunctional protein containing two sterol-carrier protein-2 domains in lipid uptake and trafficking in Toxoplasma.[Pubmed]
|
|
| Clinical and neuropathological picture of familial encephalopathy with bifunctional protein deficiency.[Pubmed]
|
|
| Normal very-long-chain fatty acids in peroxisomal D-bifunctional protein deficiency: a diagnostic pitfall.[Pubmed]
|
|
| Optico-cochleo-dentate degeneration associated with severe peripheral neuropathy and caused by peroxisomal D-bifunctional protein deficiency.[Pubmed]
|
|
| Characteristic acylcarnitine profiles in inherited defects of peroxisome biogenesis: a novel tool for screening diagnosis using tandem mass spectrometry.[Pubmed]
|
|
| Molecular analysis of genomic DNA allows rapid, and accurate, prenatal diagnosis of peroxisomal D-bifunctional protein deficiency.[Pubmed]
|
|
| Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency.[Pubmed]
|
|
| A common ancestor for Candida tropicalis and dehydrogenases that synthesize antibiotics and steroids.[Pubmed]
|
|
| Insulin-degrading enzyme exists inside of rat liver peroxisomes and degrades oxidized proteins.[Pubmed]
|
|
| The rat insulin-degrading enzyme. Molecular cloning and characterization of tissue-specific transcripts.[Pubmed]
|
|
| Insulin degrading enzyme is expressed in the human cerebrovascular endothelium and in cultured human cerebrovascular endothelial cells.[Pubmed]
|
|
| Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation.[Pubmed]
|
|
| Insulin-degrading enzyme.[Pubmed]
|
|
| Regulation of isocitrate metabolism in peroxisomes in Tetrahymena pyriformis.[Pubmed]
|
|
| Isolation of peroxisomes from rat liver using sucrose and Percoll gradients.[Pubmed]
|
|
| Liver peroxisomes, cytology and function.[Pubmed]
|
|
| The synthesis and turnover of rat liver peroxisomes. I. Fractionation of peroxisome proteins.[Pubmed]
|
|
| Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast.[Pubmed]
|
|
| Cloning and expression of Aspergillus niger icdA gene encoding mitochondrial NADP+-specific isocitrate dehydrogenase.[Pubmed]
|
|
| Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases.[Pubmed]
|
|
| A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans.[Pubmed]
|
|
| The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase.[Pubmed]
|
|
| Sources of NADPH and expression of mammalian NADP+-specific isocitrate dehydrogenases in Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions.[Pubmed]
|
|
| IDP3 encodes a peroxisomal NADP-dependent isocitrate dehydrogenase required for the beta-oxidation of unsaturated fatty acids.[Pubmed]
|
|
| Gene analysis of an NADP-linked isocitrate dehydrogenase localized in peroxisomes of the n-alkane-assimilating yeast Candida tropicalis.[Pubmed]
|
|
| Immunochemically distinct NADP-linked isocitrate dehydrogenase isozymes in mitochondria and peroxisomes of Candida tropicalis.[Pubmed]
|
|
| Novel NADP-linked isocitrate dehydrogenase present in peroxisomes of n-alkane-utilizing yeast, Candida tropicalis: comparison with mitochondrial NAD-linked isocitrate dehydrogenase.[Pubmed]
|
|
| Sequence-based discovery of the human and rodent peroxisomal proteome.[Pubmed]
|
|
| Cloning and subcellular localization of hamster and rat isopentenyl diphosphate dimethylallyl diphosphate isomerase. A PTS1 motif targets the enzyme to peroxisomes.[Pubmed]
|
|
| Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.[Pubmed]
|
|
| Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes.[Pubmed]
|
|
| L-Carnitine alters nitric oxide synthase activity in fibroblasts depending on the peroxisomal status.[Pubmed]
|
|
| Nitric oxide regulates peroxisomal enzyme activities.[Pubmed]
|
|
| Canova, a Brazilian medical formulation, alters oxidative metabolism of mice macrophages.[Pubmed]
|
|
| Hansenula polymorpha pex11 cells are affected in peroxisome retention.[Pubmed]
|
|
| Sharing the wealth: peroxisome inheritance in budding yeast.[Pubmed]
|
|
| The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae.[Pubmed]
|
|
| Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae.[Pubmed]
|
|
| Dual specificities of the glyoxysomal/peroxisomal processing protease Deg15 in higher plants.[Pubmed]
|
|
| Multiple intracellular locations of Lon protease in Arabidopsis: evidence for the localization of AtLon4 to chloroplasts.[Pubmed]
|
|
| Degradation of excess peroxisomes in mammalian liver cells by autophagy and other mechanisms.[Pubmed]
|
|
| Induction of peroxisomal Lon protease in rat liver after di-(2-ethylhexyl)phthalate treatment.[Pubmed]
|
|
| Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.[Pubmed]
|
|
| Lysine-alpha-ketoglutarate reductase and saccharopine dehydrogenase are located only in the mitochondrial matrix in rat liver.[Pubmed]
|
|
| The DEG15 serine protease cleaves peroxisomal targeting signal 2-containing proteins in Arabidopsis.[Pubmed]
|
|
| Arabidopsis peroxisomal malate dehydrogenase functions in beta-oxidation but not in the glyoxylate cycle.[Pubmed]
|
|
| Association of monoamine oxidase and malate dehydrogenase with liver peroxisomes of genetically obese (ob/ob and db/db) mice.[Pubmed]
|
|
| Effect of clofibrate on plasma lipid concentration and liver malic enzyme gene expression in rats with experimental chronic renal failure.[Pubmed]
|
|
| Subcellular localization and properties of glyoxylate cycle enzymes in the liver of rats with alloxan diabetes.[Pubmed]
|
|
| Effects of bromocriptine on pituitary organelle marker enzyme activities in lactating and postlactating rats: selective activation of lysosomal prolactin proteolytic activity.[Pubmed]
|
|
| Analytical subcellular fractionation studies on enterocytes from the jejunum and ileum of the rat and some properties of brush-border alkaline phosphatase.[Pubmed]
|
|
| Analysis of the carboxyl-terminal peroxisomal targeting signal 1 in a homologous context in Saccharomyces cerevisiae.[Pubmed]
|
|
| Expression and function of a mislocalized form of peroxisomal malate dehydrogenase (MDH3) in yeast.[Pubmed]
|
|
| The methylotrophic yeast Hansenula polymorpha contains an inducible import pathway for peroxisomal matrix proteins with an N-terminal targeting signal (PTS2 proteins).[Pubmed]
|
|
| Some aspects of regulation of peroxisomes and mitochondria in yeast.[Pubmed]
|
|
| Subcellular fractionation of rectal biopsy homogenates from patients with inflammatory bowel disease.[Pubmed]
|
|
| Morphological and biochemical studies of a naturally occurring enteropathy in the Irish setter dog: a comparison with coeliac disease in man.[Pubmed]
|
|
| Lymphocyte enzyme activities in immunodeficiency syndromes with particular reference to common variable hypogammaglobulinaemia.[Pubmed]
|
|
| Enzyme analysis and subcellular fractionation of human peripheral blood lymphocytes with special reference to the localization of putative plasma membrane enzymes.[Pubmed]
|
|
| Characterisation of gut hormone storage granules from normal human jejunum using metrizamide density gradients.[Pubmed]
|
|
| Subcellular fractionation studies of human rectal mucosa: localization of the mucosal peptide hormones.[Pubmed]
|
|
| Subcellular fractionation studies of human gastric antrum: localization of the mucosal peptide hormones.[Pubmed]
|
|
| Analytical subcellular fractionation of needle-biopsy specimens from human liver.[Pubmed]
|
|
| Malate dehydrogenase isoenzymes: cellular locations and role in the flow of metabolites between the cytoplasm and cell organelles.[Pubmed]
|
|
| Peroxisome-associated matrix protein degradation in Arabidopsis.[Pubmed]
|
|
| When is a peroxisome not a peroxisome?[Pubmed]
|
|
| Non-coordinate expression of peroxisome biogenesis, beta-oxidation and glyoxylate cycle genes in mature Arabidopsis plants.[Pubmed]
|
|
| Transport of chimeric proteins that contain a carboxy-terminal targeting signal into plant microbodies.[Pubmed]
|
|
| Targeting of glyoxysomal proteins to peroxisomes in leaves and roots of a higher plant.[Pubmed]
|
|
| Glyoxylate cycle in the epiphyseal growth plate: isocitrate lyase and malate synthase identified in mammalian cartilage.[Pubmed]
|
|
| The activity of the glyoxylate cycle in peroxisomes of Candida albicans depends on a functional beta-oxidation pathway: evidence for reduced metabolite transport across the peroxisomal membrane.[Pubmed]
|
|
| Targeting of malate synthase 1 to the peroxisomes of Saccharomyces cerevisiae cells depends on growth on oleic acid medium.[Pubmed]
|
|
| Purification of peroxisomal malate synthase from alkane-grown Candida tropicalis and some properties of the purified enzyme.[Pubmed]
|
|
| Mitochondrial and peroxisomal fractions derived from human white adipocytes.[Pubmed]
|
|
| Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans.[Pubmed]
|
|
| Molecular organisation of the malate synthase genes of Aspergillus nidulans and Neurospora crassa.[Pubmed]
|
|
| Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes.[Pubmed]
|
|
| MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency.[Pubmed]
|
|
| The molecular basis of malonyl-CoA decarboxylase deficiency.[Pubmed]
|
|
| Cloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylase.[Pubmed]
|
|
| Malonyl-CoA, a key signaling molecule in mammalian cells.[Pubmed]
|
|
| MLYCD mutation analysis: evidence for protein mistargeting as a cause of MLYCD deficiency.[Pubmed]
|
|
| Arabidopsis 22-kilodalton peroxisomal membrane protein. Nucleotide sequence analysis and biochemical characterization.[Pubmed]
|
|
| A novel alternative spliced Mpv17-like protein isoform localizes in cytosol and is expressed in a kidney- and adult-specific manner.[Pubmed]
|
|
| M-LP, Mpv17-like protein, has a peroxisomal membrane targeting signal comprising a transmembrane domain and a positively charged loop and up-regulates expression of the manganese superoxide dismutase gene.[Pubmed]
|
|
| Cloning, mapping, genomic organization, and expression of mouse M-LP, a new member of the peroxisomal membrane protein Mpv17 domain family.[Pubmed]
|
|
| Course of renal injury in the Mpv17-deficient transgenic mouse.[Pubmed]
|
|
| Making two organelles from one: Woronin body biogenesis by peroxisomal protein sorting.[Pubmed]
|
|
| Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.[Pubmed]
|
|
| Role of peroxisomes in isoprenoid biosynthesis.[Pubmed]
|
|
| Differential deficiency of mevalonate kinase and phosphomevalonate kinase in patients with distinct defects in peroxisome biogenesis: evidence for a major role of peroxisomes in cholesterol biosynthesis.[Pubmed]
|
|
| Farnesyl-diphosphate synthase is localized in peroxisomes.[Pubmed]
|
|
| Mevalonate kinase is predominantly localized in peroxisomes and is defective in patients with peroxisome deficiency disorders.[Pubmed]
|
|
| The role of peroxisomes in cholesterol metabolism.[Pubmed]
|
|
| Mevalonate kinase is localized in rat liver peroxisomes.[Pubmed]
|
|
| A new definition for the consensus sequence of the peroxisome targeting signal type 2.[Pubmed]
|
|
| Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes.[Pubmed]
|
|
| Mevalonate kinase is a cytosolic enzyme in humans.[Pubmed]
|
|
| Cholesterol biosynthesis is not defective in peroxisome biogenesis defective fibroblasts.[Pubmed]
|
|
| Peroxisomal protein targeting and identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes.[Pubmed]
|
|
| Biochemical and genetic aspects of mevalonate kinase and its deficiency.[Pubmed]
|
|
| Cholesterol biosynthesis, peroxisomes and peroxisomal disorders: mevalonate kinase is not only deficient in Zellweger syndrome but also in rhizomelic chondrodysplasia punctata.[Pubmed]
|
|
| Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein.[Pubmed]
|
|
| The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.[Pubmed]
|
|
| Identification of the OsOPR7 gene encoding 12-oxophytodienoate reductase involved in the biosynthesis of jasmonic acid in rice.[Pubmed]
|
|
| Characterization and cDNA-microarray expression analysis of 12-oxophytodienoate reductases reveals differential roles for octadecanoid biosynthesis in the local versus the systemic wound response.[Pubmed]
|
|
| Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.[Pubmed]
|
|
| A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.[Pubmed]
|
|
| Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis.[Pubmed]
|
|
| In situ substrate specificity and ultrastructural localization of polyamine oxidase activity in unfixed rat tissues.[Pubmed]
|
|
| Oxidation of oxalate and polyamines by rat peroxisomes.[Pubmed]
|
|
| Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase.[Pubmed]
|
|
| Primary structure and expression of peroxisomal acetylspermidine oxidase in the methylotrophic yeast Candida boidinii.[Pubmed]
|
|
| Analysis of the alternative pathways for the beta-oxidation of unsaturated fatty acids using transgenic plants synthesizing polyhydroxyalkanoates in peroxisomes.[Pubmed]
|
|
| The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase.[Pubmed]
|
|
| Effect of sorbic acid feeding on peroxisomes and sorboyl-CoA metabolizing enzymes in mouse liver. Selective induction of 2,4-dienoyl-CoA hydratase.[Pubmed]
|
|
| Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase.[Pubmed]
|
|
| Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. Molecular characterization.[Pubmed]
|
|
| Analysis of the acyl-CoAs that accumulate during the peroxisomal beta-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid.[Pubmed]
|
|
| Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.[Pubmed]
|
|
| Regulation of the biosynthesis of 4,7,10,13,16,19-docosahexaenoic acid.[Pubmed]
|
|
| Peroxisomes contain delta 3,5,delta 2,4-dienoyl-CoA isomerase and thus possess all enzymes required for the beta-oxidation of unsaturated fatty acids by a novel reductase-dependent pathway.[Pubmed]
|
|
| Double bond removal from odd-numbered carbons during peroxisomal beta-oxidation of arachidonic acid requires both 2,4-dienoyl-CoA reductase and delta 3,5,delta 2,4-dienoyl-CoA isomerase.[Pubmed]
|
|
| Delta 3,5, delta 2,4-dienoyl-CoA isomerase from rat liver mitochondria. Purification and characterization of a new enzyme involved in the beta-oxidation of unsaturated fatty acids.[Pubmed]
|
|
| The existence of two mitochondrial isoforms of 2,4-dienoyl-CoA reductase in the rat.[Pubmed]
|
|
| Immunocytochemical localization of delta 3, delta 2-enoyl-CoA isomerase and NADPH-dependent-2,4-dienoyl-CoA reductase in rat kidney.[Pubmed]
|
|
| Metabolic aspects of peroxisomal beta-oxidation.[Pubmed]
|
|
| Peroxisomes and beta-oxidation of long-chain unsaturated carboxylic acids.[Pubmed]
|
|
| The known purified mammalian 2,4-dienoyl-CoA reductases are mitochondrial isoenzymes.[Pubmed]
|
|
| Total and peroxisomal oxidation of various saturated and unsaturated fatty acids in rat liver, heart and m. quadriceps.[Pubmed]
|
|
| Beta-oxidation of polyunsaturated fatty acids in peroxisomes. Subcellular distribution of delta 3,delta 2-enoyl-CoA isomerase activity in rat liver.[Pubmed]
|
|
| beta-Oxidation of polyunsaturated fatty acids by rat liver peroxisomes. A role for 2,4-dienoyl-coenzyme A reductase in peroxisomal beta-oxidation.[Pubmed]
|
|
| 3-Hydroxyacyl-CoA epimerases of rat liver peroxisomes and Escherichia coli function as auxiliary enzymes in the beta-oxidation of polyunsaturated fatty acids.[Pubmed]
|
|
| Effect of growth hormone on fatty acid oxidation: growth hormone increases the activity of 2,4-dienoyl-CoA reductase in mitochondria.[Pubmed]
|
|
| Studies on the metabolism of unsaturated fatty acids. XV. Purification and properties of 2,4-dienoyl-CoA reductase from rat liver peroxisomes.[Pubmed]
|
|
| Studies on the metabolism of unsaturated fatty acids. XI. Alterations in the activities of enoyl-CoA hydratase, 3-hydroxyacyl-CoA epimerase and 2,4-dienyl-CoA reductase in rat liver mitochondria and peroxisomes by clofibrate.[Pubmed]
|
|
| Degradation of unsaturated fatty acids in peroxisomes. Existence of a 2,4-dienoyl-CoA reductase pathway.[Pubmed]
|
|
| Analysis of the beta-oxidation of trans-unsaturated fatty acid in recombinant Saccharomyces cerevisiae expressing a peroxisomal PHA synthase reveals the involvement of a reductase-dependent pathway.[Pubmed]
|
|
| Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology.[Pubmed]
|
|
| Function of human mitochondrial 2,4-dienoyl-CoA reductase and rat monofunctional Delta3-Delta2-enoyl-CoA isomerase in beta-oxidation of unsaturated fatty acids.[Pubmed]
|
|
| A novel element in the promoter of the Saccharomyces cerevisiae gene SPS19 enhances ORE-dependent up-regulation in oleic acid and is essential for de-repression.[Pubmed]
|
|
| The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19.[Pubmed]
|
|
| Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site.[Pubmed]
|
|
| Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.[Pubmed]
|
|
| Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis.[Pubmed]
|
|
| Different (13)CO(2) recovery of orally administered [1-(13)C]- and [8-(13)C] triolein in postprandial humans: an effect of phosphoenolpyruvate-carboxykinase (EC 4.1.1.32) in peripheral tissues?[Pubmed]
|
|
| A quantitative analysis of metabolite fluxes along some of the pathways of intermediary metabolism in Tetrahymena pyriformis.[Pubmed]
|
|
| Functional classification of Arabidopsis peroxisome biogenesis factors proposed from analyses of knockdown mutants.[Pubmed]
|
|
| Stress induces peroxisome biogenesis genes.[Pubmed]
|
|
| Crystallographic characterization of the N-terminal domain of PEX1.[Pubmed]
|
|
| Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain.[Pubmed]
|
|
| Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export.[Pubmed]
|
|
| Genetic heterogeneity of peroxisome biogenesis disorders among Japanese patients: evidence for a founder haplotype for the most common PEX10 gene mutation.[Pubmed]
|
|
| The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes.[Pubmed]
|
|
| Phenotype-genotype relationships in peroxisome biogenesis disorders of PEX1-defective complementation group 1 are defined by Pex1p-Pex6p interaction.[Pubmed]
|
|
| Temperature-sensitive mutation of PEX6 in peroxisome biogenesis disorders in complementation group C (CG-C): comparative study of PEX6 and PEX1.[Pubmed]
|
|
| Isolation of Penicillium chrysogenum PEX1 and PEX6 encoding AAA proteins involved in peroxisome biogenesis.[Pubmed]
|
|
| A cytoplasmic AAA family peroxin, Pex1p, interacts with Pex6p.[Pubmed]
|
|
| The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function.[Pubmed]
|
|
| The common phospholipid-binding activity of the N-terminal domains of PEX1 and VCP/p97.[Pubmed]
|
|
| Functional association of the AAA complex and the peroxisomal importomer.[Pubmed]
|
|
| Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.[Pubmed]
|
|
| Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p.[Pubmed]
|
|
| The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells.[Pubmed]
|
|
| A novel family of longer chain length dolichols present in oleate-induced yeast Saccharomyces cerevisiae.[Pubmed]
|
|
| Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I.[Pubmed]
|
|
| Human PEX1 is mutated in complementation group 1 of the peroxisome biogenesis disorders.[Pubmed]
|
|
| Role of the PAS1 gene of Pichia pastoris in peroxisome biogenesis.[Pubmed]
|
|
| Effect of site-directed mutagenesis of conserved lysine residues upon Pas1 protein function in peroxisome biogenesis.[Pubmed]
|
|
| Peroxisome biogenesis in the yeast Yarrowia lipolytica.[Pubmed]
|
|
| Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis.[Pubmed]
|
|
| Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica.[Pubmed]
|
|
| Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders.[Pubmed]
|
|
| Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p involved in shuttling of the PTS1 receptor Pex5p in peroxisome biogenesis.[Pubmed]
|
|
| Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p.[Pubmed]
|
|
| A temperature-sensitive CHO pex1 mutant with a novel mutation in the AAA Walker A1 motif.[Pubmed]
|
|
| Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.[Pubmed]
|
|
| Genetic and clinical aspects of Zellweger spectrum patients with PEX1 mutations.[Pubmed]
|
|
| PEX1 mutations in the Zellweger spectrum of the peroxisome biogenesis disorders.[Pubmed]
|
|
| Orthotopic liver transplantation from a living-related donor in an infant with a peroxisome biogenesis defect of the infantile Refsum disease type.[Pubmed]
|
|
| Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.[Pubmed]
|
|
| Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis.[Pubmed]
|
|
| The PEX Gene Screen: molecular diagnosis of peroxisome biogenesis disorders in the Zellweger syndrome spectrum.[Pubmed]
|
|
| PEX1 deficiency presenting as Leber congenital amaurosis.[Pubmed]
|
|
| Metabolic and molecular basis of peroxisomal disorders: a review.[Pubmed]
|
|
| Peroxisome biogenesis disorders with prolonged survival: phenotypic expression in a cohort of 31 patients.[Pubmed]
|
|
| Neuroimaging of peroxisome biogenesis disorders (Zellweger spectrum) with prolonged survival.[Pubmed]
|
|
| Is there a phenotype/genotype correlation in peroxisome biogenesis disorders (PBDs)?[Pubmed]
|
|
| Novel PEX1 mutations and genotype-phenotype correlations in Australasian peroxisome biogenesis disorder patients.[Pubmed]
|
|
| PEX1 mutations in complementation group 1 of Zellweger spectrum patients correlate with severity of disease.[Pubmed]
|
|
| The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder.[Pubmed]
|
|
| Disorders of peroxisome biogenesis due to mutations in PEX1: phenotypes and PEX1 protein levels.[Pubmed]
|
|
| Identification of a common PEX1 mutation in Zellweger syndrome.[Pubmed]
|
|
| Mutations in PEX1 in peroxisome biogenesis disorders: G843D and a mild clinical phenotype.[Pubmed]
|
|
| Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders.[Pubmed]
|
|
| Requirement of the C3HC4 zinc RING finger of the Arabidopsis PEX10 for photorespiration and leaf peroxisome contact with chloroplasts.[Pubmed]
|
|
| AtPEX2 and AtPEX10 are targeted to peroxisomes independently of known endoplasmic reticulum trafficking routes.[Pubmed]
|
|
| An Arabidopsis pex10 null mutant is embryo lethal, implicating peroxisomes in an essential role during plant embryogenesis.[Pubmed]
|
|
| AthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis.[Pubmed]
|
|
| Biochemical and molecular approaches to understanding protein import into peroxisomes.[Pubmed]
|
|
| Conservation of PEX19-binding motifs required for protein targeting to mammalian peroxisomal and trypanosome glycosomal membranes.[Pubmed]
|
|
| Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome.[Pubmed]
|
|
| Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery.[Pubmed]
|
|
| Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris.[Pubmed]
|
|
| Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders.[Pubmed]
|
|
| A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts.[Pubmed]
|
|
| Zellweger syndrome resulting from maternal isodisomy of chromosome 1.[Pubmed]
|
|
| Identification of novel mutations in PEX2, PEX6, PEX10, PEX12, and PEX13 in Zellweger spectrum patients.[Pubmed]
|
|
| Genetic heterogeneity in Japanese patients with peroxisome biogenesis disorders and evidence for a founder haplotype for the most common mutation in PEX10 gene.[Pubmed]
|
|
| Phenotype-genotype relationships in PEX10-deficient peroxisome biogenesis disorder patients.[Pubmed]
|
|
| PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.[Pubmed]
|
|
| Characterization of glycosomal RING finger proteins of trypanosomatids.[Pubmed]
|
|
| Identification and characterization of three peroxins--PEX6, PEX10 and PEX12--involved in glycosome biogenesis in Trypanosoma brucei.[Pubmed]
|
|
| Arabidopsis PEROXIN11c-e, FISSION1b, and DYNAMIN-RELATED PROTEIN3A cooperate in cell cycle-associated replication of peroxisomes.[Pubmed]
|
|
| The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.[Pubmed]
|
|
| Five Arabidopsis peroxin 11 homologs individually promote peroxisome elongation, duplication or aggregation.[Pubmed]
|
|
| Peroxisomes in airway epithelia and future prospects of these organelles for pulmonary cell biology.[Pubmed]
|
|
| PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function.[Pubmed]
|
|
| Peroxisome biogenesis: where Arf and coatomer might be involved.[Pubmed]
|
|
| ARF- and coatomer-mediated peroxisomal vesiculation.[Pubmed]
|
|
| Maintaining peroxisome populations: a story of division and inheritance.[Pubmed]
|
|
| Conserved function of pex11p and the novel pex25p and pex27p in peroxisome biogenesis.[Pubmed]
|
|
| Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae.[Pubmed]
|
|
| YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.[Pubmed]
|
|
| PEX11 promotes peroxisome division independently of peroxisome metabolism.[Pubmed]
|
|
| Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11.[Pubmed]
|
|
| Elongation and clustering of glycosomes in Trypanosoma brucei overexpressing the glycosomal Pex11p.[Pubmed]
|
|
| Redox-sensitive homodimerization of Pex11p: a proposed mechanism to regulate peroxisomal division.[Pubmed]
|
|
| Pmp27 promotes peroxisomal proliferation.[Pubmed]
|
|
| Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p.[Pubmed]
|
|
| Environmental response of yeast peroxisomes. Aspects of organelle assembly and degradation.[Pubmed]
|
|
| Peroxisome synthesis in the absence of preexisting peroxisomes.[Pubmed]
|
|
| Disruption of the Aopex11-1 gene involved in peroxisome proliferation leads to impaired Woronin body formation in Aspergillus oryzae.[Pubmed]
|
|
| Depletion of GIM5 causes cellular fragility, a decreased glycosome number, and reduced levels of ether-linked phospholipids in trypanosomes.[Pubmed]
|
|
| Molecular components required for the targeting of PEX7 to peroxisomes in Arabidopsis thaliana.[Pubmed]
|
|
| The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes.[Pubmed]
|
|
| The Arabidopsis PEX12 gene is required for peroxisome biogenesis and is essential for development.[Pubmed]
|
|
| Characterization of the mammalian peroxisomal import machinery: Pex2p, Pex5p, Pex12p, and Pex14p are subunits of the same protein assembly.[Pubmed]
|
|
| Isolation and characterization of novel peroxisome biogenesis-defective Chinese hamster ovary cell mutants using green fluorescent protein.[Pubmed]
|
|
| PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p.[Pubmed]
|
|
| PEX12 encodes an integral membrane protein of peroxisomes.[Pubmed]
|
|
| Pex12p of Saccharomyces cerevisiae is a component of a multi-protein complex essential for peroxisomal matrix protein import.[Pubmed]
|
|
| Novel mutations in the PEX12 gene of patients with a peroxisome biogenesis disorder.[Pubmed]
|
|
| PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12.[Pubmed]
|
|
| The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly.[Pubmed]
|
|
| Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences.[Pubmed]
|
|
| Phenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disorders.[Pubmed]
|
|
| Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor.[Pubmed]
|
|
| Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype.[Pubmed]
|
|
| Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision.[Pubmed]
|
|
| Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes.[Pubmed]
|
|
| Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene.[Pubmed]
|
|
| Isolation, characterization and mutation analysis of PEX13-defective Chinese hamster ovary cell mutants.[Pubmed]
|
|
| Peroxisomal targeting of PTS2 pre-import complexes in the yeast Saccharomyces cerevisiae.[Pubmed]
|
|
| Pex13p: docking or cargo handling protein?[Pubmed]
|
|
| Membrane association of the cycling peroxisome import receptor Pex5p.[Pubmed]
|
|
| Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.[Pubmed]
|
|
| Identification of a novel, intraperoxisomal pex14-binding site in pex13: association of pex13 with the docking complex is essential for peroxisomal matrix protein import.[Pubmed]
|
|
| The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p.[Pubmed]
|
|
| Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain.[Pubmed]
|
|
| Interactions of Pex7p and Pex18p/Pex21p with the peroxisomal docking machinery: implications for the first steps in PTS2 protein import.[Pubmed]
|
|
| Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.[Pubmed]
|
|
| Interaction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p.[Pubmed]
|
|
| Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes.[Pubmed]
|
|
| Pex5p, the peroxisomal cycling receptor, is a monomeric non-globular protein.[Pubmed]
|
|
| Potential role for Pex19p in assembly of PTS-receptor docking complexes.[Pubmed]
|
|
| Building new models for peroxisome biogenesis.[Pubmed]
|
|
| The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction.[Pubmed]
|
|
| Nonsense and temperature-sensitive mutations in PEX13 are the cause of complementation group H of peroxisome biogenesis disorders.[Pubmed]
|
|
| Identification, characterization and essentiality of the unusual peroxin 13 from Trypanosoma brucei.[Pubmed]
|
|
| Cloning of two splice variants of the rice PTS1 receptor, OsPex5pL and OsPex5pS, and their functional characterization using pex5-deficient yeast and Arabidopsis.[Pubmed]
|
|
| Direct interaction and determination of binding domains among peroxisomal import factors in Arabidopsis thaliana.[Pubmed]
|
|
| AtPex14p maintains peroxisomal functions by determining protein targeting to three kinds of plant peroxisomes.[Pubmed]
|
|
| Antibodies against pex14p block ATP-independent binding of matrix proteins to peroxisomes in vitro.[Pubmed]
|
|
| Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p.[Pubmed]
|
|
| Molecular mechanisms of import of peroxisome-targeting signal type 2 (PTS2) proteins by PTS2 receptor Pex7p and PTS1 receptor Pex5pL.[Pubmed]
|
|
| The import competence of a peroxisomal membrane protein is determined by Pex19p before the docking step.[Pubmed]
|
|
| Characterization of the peroxisomal cycling receptor, Pex5p, using a cell-free in vitro import system.[Pubmed]
|
|
| Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein.[Pubmed]
|
|
| The mammalian peroxin Pex5pL, the longer isoform of the mobile peroxisome targeting signal (PTS) type 1 transporter, translocates the Pex7p.PTS2 protein complex into peroxisomes via its initial docking site, Pex14p.[Pubmed]
|
|
| PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.[Pubmed]
|
|
| Biochemical methods to monitor autophagy-related processes in yeast.[Pubmed]
|
|
| Pex14p, more than just a docking protein.[Pubmed]
|
|
| Pex14p is not required for N-starvation induced microautophagy and in catalytic amounts for macropexophagy in Hansenula polymorpha.[Pubmed]
|
|
| Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites.[Pubmed]
|
|
| Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae.[Pubmed]
|
|
| Saccharomyces cerevisiae Pex14p contains two independent Pex5p binding sites, which are both essential for PTS1 protein import.[Pubmed]
|
|
| Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE.[Pubmed]
|
|
| Opinion: peroxisomal-protein import: is it really that complex?[Pubmed]
|
|
| NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor.[Pubmed]
|
|
| Peroxisomal membrane protein import does not require Pex17p.[Pubmed]
|
|
| Peroxisome biogenesis and selective degradation converge at Pex14p.[Pubmed]
|
|
| Hansenula polymorpha Pex14p phosphorylated in vivo.[Pubmed]
|
|
| Pichia pastoris Pex14p, a phosphorylated peroxisomal membrane protein, is part of a PTS-receptor docking complex and interacts with many peroxins.[Pubmed]
|
|
| Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.[Pubmed]
|
|
| The peroxisomal membrane protein Pex14p of Hansenula polymorpha is phosphorylated in vivo.[Pubmed]
|
|
| The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis.[Pubmed]
|
|
| Pex14p is a member of the protein linkage map of Pex5p.[Pubmed]
|
|
| Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways.[Pubmed]
|
|
| Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering.[Pubmed]
|
|
| Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.[Pubmed]
|
|
| Identification of a novel PEX14 mutation in Zellweger syndrome.[Pubmed]
|
|
| Molecular and clinical aspects of peroxisomal diseases.[Pubmed]
|
|
| Molecular and neurologic findings of peroxisome biogenesis disorders.[Pubmed]
|
|
| Modulation of the Leishmania donovani peroxin 5 quaternary structure by peroxisomal targeting signal 1 ligands.[Pubmed]
|
|
| The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.[Pubmed]
|
|
| Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.[Pubmed]
|
|
| Analysis of the sequence motifs responsible for the interactions of peroxins 14 and 5, which are involved in glycosome biogenesis in Trypanosoma brucei.[Pubmed]
|
|
| Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins.[Pubmed]
|
|
| Peroxisomal targeting protein 14 (PEX14) from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.[Pubmed]
|
|
| Glucose is toxic to glycosome-deficient trypanosomes.[Pubmed]
|
|
| Leishmania donovani peroxin 14 undergoes a marked conformational change following association with peroxin 5.[Pubmed]
|
|
| Peroxin 5-peroxin 14 association in the protozoan Leishmania donovani involves a novel protein-protein interaction motif.[Pubmed]
|
|
| Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites.[Pubmed]
|
|
| Pex15p of Saccharomyces cerevisiae provides a molecular basis for recruitment of the AAA peroxin Pex6p to peroxisomal membranes.[Pubmed]
|
|
| Peroxisome biogenesis: back to the endoplasmic reticulum?[Pubmed]
|
|
| Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membrane.[Pubmed]
|
|
| Arabidopsis peroxin 16 coexists at steady state in peroxisomes and endoplasmic reticulum.[Pubmed]
|
|
| The Pex16p homolog SSE1 and storage organelle formation in Arabidopsis seeds.[Pubmed]
|
|
| The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.[Pubmed]
|
|
| Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.[Pubmed]
|
|
| Enlarged peroxisomes are present in oleic acid-grown Yarrowia lipolytica overexpressing the PEX16 gene encoding an intraperoxisomal peripheral membrane peroxin.[Pubmed]
|
|
| Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins.[Pubmed]
|
|
| Peroxisomal membrane proteins are properly targeted to peroxisomes in the absence of COPI- and COPII-mediated vesicular transport.[Pubmed]
|
|
| Pex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal-receptor docking complex in Pichia pastoris.[Pubmed]
|
|
| Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery.[Pubmed]
|
|
| The peroxin Pex17p of the yeast Yarrowia lipolytica is associated peripherally with the peroxisomal membrane and is required for the import of a subset of matrix proteins.[Pubmed]
|
|
| Uniqueness of the mechanism of protein import into the peroxisome matrix: transport of folded, co-factor-bound and oligomeric proteins by shuttling receptors.[Pubmed]
|
|
| Yarrowia lipolytica Pex20p, Saccharomyces cerevisiae Pex18p/Pex21p and mammalian Pex5pL fulfil a common function in the early steps of the peroxisomal PTS2 import pathway.[Pubmed]
|
|
| Pex18p is constitutively degraded during peroxisome biogenesis.[Pubmed]
|
|
| Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p.[Pubmed]
|
|
| Peroxin Pex21p interacts with the C-terminal noncatalytic domain of yeast seryl-tRNA synthetase and forms a specific ternary complex with tRNA(Ser).[Pubmed]
|
|
| Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4.[Pubmed]
|
|
| Role of Pex19p in the targeting of PMP70 to peroxisome.[Pubmed]
|
|
| Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes.[Pubmed]
|
|
| In vitro transport of membrane proteins to peroxisomes by shuttling receptor Pex19p.[Pubmed]
|
|
| Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes.[Pubmed]
|
|
| The N-domain of Pex22p can functionally replace the Pex3p N-domain in targeting and peroxisome formation.[Pubmed]
|
|
| The host Pex19p plays a role in peroxisomal localization of tombusvirus replication proteins.[Pubmed]
|
|
| Exploiting alternative subcellular location for replication: tombusvirus replication switches to the endoplasmic reticulum in the absence of peroxisomes.[Pubmed]
|
|
| Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions.[Pubmed]
|
|
| Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.[Pubmed]
|
|
| Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.[Pubmed]
|
|
| Contribution of the endoplasmic reticulum to peroxisome formation.[Pubmed]
|
|
| Biogenesis of peroxisomes. Topogenesis of the peroxisomal membrane and matrix proteins.[Pubmed]
|
|
| Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals.[Pubmed]
|
|
| PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins.[Pubmed]
|
|
| Hansenula polymorpha Pex19p is essential for the formation of functional peroxisomal membranes.[Pubmed]
|
|
| Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins.[Pubmed]
|
|
| Identification and characterization of the human peroxin PEX3.[Pubmed]
|
|
| Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly.[Pubmed]
|
|
| Pex19p, a farnesylated protein essential for peroxisome biogenesis.[Pubmed]
|
|
| Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein.[Pubmed]
|
|
| Yarrowia lipolytica cells mutant for the peroxisomal peroxin Pex19p contain structures resembling wild-type peroxisomes.[Pubmed]
|
|
| Targeting of hFis1 to peroxisomes is mediated by Pex19p.[Pubmed]
|
|
| Characterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 IN Pex3p as a critical residue for the interaction.[Pubmed]
|
|
| Interaction of PEX3 and PEX19 visualized by fluorescence resonance energy transfer (FRET).[Pubmed]
|
|
| PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins.[Pubmed]
|
|
| The interaction between human PEX3 and PEX19 characterized by fluorescence resonance energy transfer (FRET) analysis.[Pubmed]
|
|
| PxF, a prenylated protein of peroxisomes.[Pubmed]
|
|
| Identification of trypanosomatid PEX19: functional characterization reveals impact on cell growth and glycosome size and number.[Pubmed]
|
|
| Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress.[Pubmed]
|
|
| Bile acid treatment alters hepatic disease and bile acid transport in peroxisome-deficient PEX2 Zellweger mice.[Pubmed]
|
|
| Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain.[Pubmed]
|
|
| Abnormal cerebellar histogenesis in PEX2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency.[Pubmed]
|
|
| The peroxisome deficient PEX2 Zellweger mouse: pathologic and biochemical correlates of lipid dysfunction.[Pubmed]
|
|
| Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder.[Pubmed]
|
|
| Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent.[Pubmed]
|
|
| Isolation and characterization of peroxisome-deficient Chinese hamster ovary cell mutants representing human complementation group III.[Pubmed]
|
|
| Isolation of a new peroxisome-deficient CHO cell mutant defective in peroxisome targeting signal-1 receptor.[Pubmed]
|
|
| Novel mutations in the PEX2 gene of four unrelated patients with a peroxisome biogenesis disorder.[Pubmed]
|
|
| The peroxisomal membrane targeting elements of human peroxin 2 (PEX2).[Pubmed]
|
|
| Compartmentation of enzymes in a microbody, the glycosome, is essential in Trypanosoma brucei.[Pubmed]
|
|
| Pex7p and Pex20p of Neurospora crassa function together in PTS2-dependent protein import into peroxisomes.[Pubmed]
|
|
| A role for the peroxin Pex8p in Pex20p-dependent thiolase import into peroxisomes of the yeast Yarrowia lipolytica.[Pubmed]
|
|
| Identification and functional characterization of Arabidopsis PEROXIN4 and the interacting protein PEROXIN22.[Pubmed]
|
|
| Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane.[Pubmed]
|
|
| Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae.[Pubmed]
|
|
| Mutants of the Yarrowia lipolytica PEX23 gene encoding an integral peroxisomal membrane peroxin mislocalize matrix proteins and accumulate vesicles containing peroxisomal matrix and membrane proteins.[Pubmed]
|
|
| Yarrowia lipolytica cells mutant for the PEX24 gene encoding a peroxisomal membrane peroxin mislocalize peroxisomal proteins and accumulate membrane structures containing both peroxisomal matrix and membrane proteins.[Pubmed]
|
|
| Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane.[Pubmed]
|
|
| Sorting pathway and molecular targeting signals for the Arabidopsis peroxin 3.[Pubmed]
|
|
| Yeast peroxisomes multiply by growth and division.[Pubmed]
|
|
| The importomer--a peroxisomal membrane complex involved in protein translocation into the peroxisome matrix.[Pubmed]
|
|
| Endoplasmic reticulum-directed Pex3p routes to peroxisomes and restores peroxisome formation in a Saccharomyces cerevisiae pex3Delta strain.[Pubmed]
|
|
| Peroxisomes: another branch of the secretory pathway?[Pubmed]
|
|
| Peroxisome membrane biogenesis: the stage is set.[Pubmed]
|
|
| Peroxisome biogenesis: advances and conundrums.[Pubmed]
|
|
| Peroxisome biogenesis occurs in an unsynchronized manner in close association with the endoplasmic reticulum in temperature-sensitive Yarrowia lipolytica Pex3p mutants.[Pubmed]
|
|
| Removal of Pex3p is an important initial stage in selective peroxisome degradation in Hansenula polymorpha.[Pubmed]
|
|
| Peroxisome remnants in pex3delta cells and the requirement of Pex3p for interactions between the peroxisomal docking and translocation subcomplexes.[Pubmed]
|
|
| Hansenula polymorpha Pex3p is a peripheral component of the peroxisomal membrane.[Pubmed]
|
|
| Normal peroxisome development from vesicles induced by truncated Hansenula polymorpha Pex3p.[Pubmed]
|
|
| Inactivation of the endoplasmic reticulum protein translocation factor, Sec61p, or its homolog, Ssh1p, does not affect peroxisome biogenesis.[Pubmed]
|
|
| A novel method to determine the topology of peroxisomal membrane proteins in vivo using the tobacco etch virus protease.[Pubmed]
|
|
| Identification of PEX3 as the gene mutated in a Zellweger syndrome patient lacking peroxisomal remnant structures.[Pubmed]
|
|
| Inhibitors of COPI and COPII do not block PEX3-mediated peroxisome synthesis.[Pubmed]
|
|
| The peroxin pex3p initiates membrane assembly in peroxisome biogenesis.[Pubmed]
|
|
| Genomic organization, expression analysis, and chromosomal localization of the mouse PEX3 gene encoding a peroxisomal assembly protein.[Pubmed]
|
|
| A stretch of positively charged amino acids at the N terminus of Hansenula polymorpha Pex3p is involved in incorporation of the protein into the peroxisomal membrane.[Pubmed]
|
|
| The human PEX3 gene encoding a peroxisomal assembly protein: genomic organization, positional mapping, and mutation analysis in candidate phenotypes.[Pubmed]
|
|
| Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: high steady-state levels of the protein fully abolish matrix protein import.[Pubmed]
|
|
| Isolation and characterization of Pas2p, a peroxisomal membrane protein essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris.[Pubmed]
|
|
| The Hansenula polymorpha PER9 gene encodes a peroxisomal membrane protein essential for peroxisome assembly and integrity.[Pubmed]
|
|
| Heterologous complementation of peroxisome function in yeast: the Saccharomyces cerevisiae PAS3 gene restores peroxisome biogenesis in a Hansenula polymorpha per9 disruption mutant.[Pubmed]
|
|
| Identification of peroxisomal membrane ghosts with an epitope-tagged integral membrane protein in yeast mutants lacking peroxisomes.[Pubmed]
|
|
| PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis.[Pubmed]
|
|
| Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport.[Pubmed]
|
|
| PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger syndrome of complementation group G.[Pubmed]
|
|
| Defective peroxisome membrane synthesis due to mutations in human PEX3 causes Zellweger syndrome, complementation group G.[Pubmed]
|
|
| Dysferlin domain-containing proteins, Pex30p and Pex31p, localized to two compartments, control the number and size of oleate-induced peroxisomes in Pichia pastoris.[Pubmed]
|
|
| A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.[Pubmed]
|
|
| Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling.[Pubmed]
|
|
| Ubiquitination of the peroxisomal import receptor Pex5p.[Pubmed]
|
|
| Peroxisomal Delta(3),Delta(2)-enoyl CoA isomerases and evolution of cytosolic paralogues in embryophytes.[Pubmed]
|
|
| Molecular and functional characterization of monocot-specific Pex5p splicing variants, using OsPex5pL and OsPex5pS from rice (Oryza sativa).[Pubmed]
|
|
| AtLACS7 interacts with the TPR domains of the PTS1 receptor PEX5.[Pubmed]
|
|
| Differential contribution of two peroxisomal protein receptors to the maintenance of peroxisomal functions in Arabidopsis.[Pubmed]
|
|
| The Arabidopsis peroxisomal targeting signal type 2 receptor PEX7 is necessary for peroxisome function and dependent on PEX5.[Pubmed]
|
|
| An Arabidopsis indole-3-butyric acid-response mutant defective in PEROXIN6, an apparent ATPase implicated in peroxisomal function.[Pubmed]
|
|
| Genetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classes.[Pubmed]
|
|
| Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.[Pubmed]
|
|
| Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver.[Pubmed]
|
|
| Mass spectrometric analysis of ceramide perturbations in brain and fibroblasts of mice and human patients with peroxisomal disorders.[Pubmed]
|
|
| Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues.[Pubmed]
|
|
| A review of morphological techniques for detection of peroxisomal (and mitochondrial) proteins and their corresponding mRNAs during ontogenesis in mice: application to the PEX5-knockout mouse with Zellweger syndrome.[Pubmed]
|
|
| Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence.[Pubmed]
|
|
| The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal beta-oxidation.[Pubmed]
|
|
| Generation of Pex5-loxP mice allowing the conditional elimination of peroxisomes.[Pubmed]
|
|
| Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse).[Pubmed]
|
|
| Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model.[Pubmed]
|
|
| Further insights into peroxisomal lipid breakdown via alpha- and beta-oxidation.[Pubmed]
|
|
| Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse.[Pubmed]
|
|
| Docosahexaenoic acid deficit is not a major pathogenic factor in peroxisome-deficient mice.[Pubmed]
|
|
| A mouse model for Zellweger syndrome.[Pubmed]
|
|
| Altered antigenic disposition of peroxisomal urate oxidase in PEX5-defective Chinese hamster ovary cells.[Pubmed]
|
|
| Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.[Pubmed]
|
|
| Dynamic architecture of the peroxisomal import receptor Pex5p.[Pubmed]
|
|
| Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins.[Pubmed]
|
|
| Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import.[Pubmed]
|
|
| Protein translocation across the peroxisomal membrane.[Pubmed]
|
|
| Modification of the monomer composition of polyhydroxyalkanoate synthesized in Saccharomyces cerevisiae expressing variants of the beta-oxidation-associated multifunctional enzyme.[Pubmed]
|
|
| Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.[Pubmed]
|
|
| The tetratricopeptide repeat domains of human, tobacco, and nematode PEX5 proteins are functionally interchangeable with the analogous native domain for peroxisomal import of PTS1-terminated proteins in yeast.[Pubmed]
|
|
| A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of alpha 2.[Pubmed]
|
|
| Identification and analysis of the plant peroxisomal targeting signal 1 receptor NtPEX5.[Pubmed]
|
|
| Cloning and sequence of a 3.835 kbp DNA fragment containing the HIS4 gene and a fragment of a PEX5-like gene from Candida albicans.[Pubmed]
|
|
| Fate and role of peroxisomes during the life cycle of the yeast Saccharomyces cerevisiae: inheritance of peroxisomes during meiosis.[Pubmed]
|
|
| Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.[Pubmed]
|
|
| The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL.[Pubmed]
|
|
| Tetratricopeptide repeat domain of Yarrowia lipolytica Pex5p is essential for recognition of the type 1 peroxisomal targeting signal but does not confer full biological activity on Pex5p.[Pubmed]
|
|
| Peroxisome targeting signal 1: is it really a simple tripeptide?[Pubmed]
|
|
| Correlating structure and affinity for PEX5:PTS1 complexes.[Pubmed]
|
|
| Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5.[Pubmed]
|
|
| A proposed model for the PEX5-peroxisomal targeting signal-1 recognition complex.[Pubmed]
|
|
| Formation of peroxisomes from peroxisomal ghosts in a peroxisome-deficient mammalian cell mutant upon complementation by protein microinjection.[Pubmed]
|
|
| An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes.[Pubmed]
|
|
| Structural insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.[Pubmed]
|
|
| Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei.[Pubmed]
|
|
| Automated affinity chromatography measurements of compound mixtures using a lab-on-valve apparatus coupled to electrospray ionization mass spectrometry.[Pubmed]
|
|
| An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.[Pubmed]
|
|
| Peroxisomal targeting signal-1 receptor protein PEX5 from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.[Pubmed]
|
|
| Cloning and analysis of the PTS-1 receptor in Trypanosoma brucei.[Pubmed]
|
|
| Jasmonate biosynthesis in Arabidopsis thaliana requires peroxisomal beta-oxidation enzymes--additional proof by properties of pex6 and aim1.[Pubmed]
|
|
| Identification and characterisation of PEX6 orthologues from plants.[Pubmed]
|
|
| Peroxisome mosaics.[Pubmed]
|
|
| The peroxin Pex6p gene is impaired in peroxisomal biogenesis disorders of complementation group 6.[Pubmed]
|
|
| Genomic structure and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders.[Pubmed]
|
|
| Loss of peroxisome function triggers necrosis.[Pubmed]
|
|
| A novel role of peroxin PEX6: suppression of aging defects in mitochondria.[Pubmed]
|
|
| Cloning of peroxisome assembly factor-2.[Pubmed]
|
|
| PAY4, a gene required for peroxisome assembly in the yeast Yarrowia lipolytica, encodes a novel member of a family of putative ATPases.[Pubmed]
|
|
| Dynamic ergosterol- and ceramide-rich domains in the peroxisomal membrane serve as an organizing platform for peroxisome fusion.[Pubmed]
|
|
| Peroxisomal membrane fusion requires two AAA family ATPases, Pex1p and Pex6p.[Pubmed]
|
|
| Fusion of small peroxisomal vesicles in vitro reconstructs an early step in the in vivo multistep peroxisome assembly pathway of Yarrowia lipolytica.[Pubmed]
|
|
| Rational diagnostic strategy for Zellweger syndrome spectrum patients.[Pubmed]
|
|
| Plasmalogens participate in very-long-chain fatty acid-induced pathology.[Pubmed]
|
|
| Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.[Pubmed]
|
|
| PEX7 gene structure, alternative transcripts, and evidence for a founder haplotype for the frequent RCDP allele, L292ter.[Pubmed]
|
|
| Isolation of Chinese hamster ovary cell pex mutants: two PEX7-defective mutants.[Pubmed]
|
|
| Pex7p translocates in and out of peroxisomes in Saccharomyces cerevisiae.[Pubmed]
|
|
| Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells.[Pubmed]
|
|
| A mobile PTS2 receptor for peroxisomal protein import in Pichia pastoris.[Pubmed]
|
|
| Protein import into peroxisomes: new developments.[Pubmed]
|
|
| Signals, receptors, and cytosolic factors involved in peroxisomal protein import.[Pubmed]
|
|
| The import receptor for the peroxisomal targeting signal 2 (PTS2) in Saccharomyces cerevisiae is encoded by the PAS7 gene.[Pubmed]
|
|
| PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.[Pubmed]
|
|
| Peroxisome biogenesis disorders.[Pubmed]
|
|
| Molecular basis of Refsum disease: sequence variations in phytanoyl-CoA hydroxylase (PHYH) and the PTS2 receptor (PEX7).[Pubmed]
|
|
| Mutation analysis of PEX7 in 60 probands with rhizomelic chondrodysplasia punctata and functional correlations of genotype with phenotype.[Pubmed]
|
|
| Mutational spectrum in the PEX7 gene and functional analysis of mutant alleles in 78 patients with rhizomelic chondrodysplasia punctata type 1.[Pubmed]
|
|
| Genotype-phenotype correlations in disorders of peroxisome biogenesis.[Pubmed]
|
|
| A novel nonsense mutation of the PEX7 gene in a patient with rhizomelic chondrodysplasia punctata.[Pubmed]
|
|
| Multiple targeting modules on peroxisomal proteins are not redundant: discrete functions of targeting signals within Pmp47 and Pex8p.[Pubmed]
|
|
| Physical interactions of the peroxisomal targeting signal 1 receptor pex5p, studied by fluorescence correlation spectroscopy.[Pubmed]
|
|
| Pex8p, an intraperoxisomal peroxin of Saccharomyces cerevisiae required for protein transport into peroxisomes binds the PTS1 receptor pex5p.[Pubmed]
|
|
| Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of saccharomyces cerevisiae involved in fatty acid metabolism.[Pubmed]
|
|
| Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase.[Pubmed]
|
|
| PEX genes in fungal genomes: common, rare or redundant.[Pubmed]
|
|
| Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.[Pubmed]
|
|
| Cloning and functional expression of a mammalian gene for a peroxisomal sarcosine oxidase.[Pubmed]
|
|
| Molecular cloning and expression of human L-pipecolate oxidase.[Pubmed]
|
|
| Enzyme cytochemical localization of sarcosine oxidase activity in the liver and kidney of several mammals.[Pubmed]
|
|
| Subcellular localization of fructosyl amino acid oxidases in peroxisomes of Aspergillus terreus and Penicillium janthinellum.[Pubmed]
|
|
| Assay for L-pipecolate oxidase activity in human liver: detection of enzyme deficiency in hyperpipecolic acidaemia.[Pubmed]
|
|
| L-pipecolic acid metabolism in human liver: detection of L-pipecolate oxidase and identification of its reaction product.[Pubmed]
|
|
| Phosphomevalonate kinase is a cytosolic protein in humans.[Pubmed]
|
|
| Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence.[Pubmed]
|
|
| Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5 A resolution.[Pubmed]
|
|
| Human mitochondrial peroxiredoxin 5 protects from mitochondrial DNA damages induced by hydrogen peroxide.[Pubmed]
|
|
| The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylcoenzyme A thioester.[Pubmed]
|
|
| Identification of PTE2, a human peroxisomal long-chain acyl-CoA thioesterase.[Pubmed]
|
|
| Characterization of acyl-CoA thioesterase activity in isolated rat liver peroxisomes. Partial purification and characterization of a long-chain acyl-CoA thioesterase.[Pubmed]
|
|
| Free flow isoelectric focusing : a method for the separation of both hydrophilic and hydrophobic proteins of rat liver peroxisomes.[Pubmed]
|
|
| Efficient separation and analysis of peroxisomal membrane proteins using free-flow isoelectric focusing.[Pubmed]
|
|
| Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell culture peroxisomes.[Pubmed]
|
|
| Import of the peroxisomal targeting signal type 2 protein 3-ketoacyl-coenzyme a thiolase into glyoxysomes.[Pubmed]
|
|
| Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane.[Pubmed]
|
|
| Novel functions of acyl-CoA thioesterases and acyltransferases as auxiliary enzymes in peroxisomal lipid metabolism.[Pubmed]
|
|
| The peroxisome: still a mysterious organelle.[Pubmed]
|
|
| X-linked adrenoleukodystrophy: clinical, biochemical and pathogenetic aspects.[Pubmed]
|
|
| Pathogenesis of peroxisomal deficiency disorders (Zellweger syndrome) may be mediated by misregulation of the GABAergic system via the diazepam binding inhibitor.[Pubmed]
|
|
| Age-related changes in peroxisomal membrane protein 70 and superoxide dismutase 1 in transgenic G93A mice.[Pubmed]
|
|
| Peroxisomes start their life in the endoplasmic reticulum.[Pubmed]
|
|
| Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Subcellular distribution of selenium in deficient mouse liver.[Pubmed]
|
|
| Peroxisomal membrane monocarboxylate transporters: evidence for a redox shuttle system?[Pubmed]
|
|
| Peptide-based targeting of fluorophores to organelles in living cells.[Pubmed]
|
|
| Insertion of the 70-kDa peroxisomal membrane protein into peroxisomal membranes in vivo and in vitro.[Pubmed]
|
|
| The 70 kDa peroxisomal membrane protein: an ATP-binding cassette transporter protein involved in peroxisome biogenesis.[Pubmed]
|
|
| Isoprenoid biosynthesis in rat liver peroxisomes. Characterization of cis-prenyltransferase and squalene synthetase.[Pubmed]
|
|
| Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy.[Pubmed]
|
|
| Biochemical effects and zonal heterogeneity of peroxisome proliferation induced by perfluorocarboxylic acids in rat liver.[Pubmed]
|
|
| Large cation-selective pores from rat liver peroxisomal membranes incorporated to planar lipid bilayers.[Pubmed]
|
|
| Peroxisome biogenesis and the role of protein import.[Pubmed]
|
|
| Convergence of model systems for peroxisome biogenesis.[Pubmed]
|
|
| Mutations in the PAY5 gene of the yeast Yarrowia lipolytica cause the accumulation of multiple subpopulations of peroxisomes.[Pubmed]
|
|
| Baicalein 5,6,7-trimethyl ether activates peroxisomal but not mitochondrial fatty acid beta-oxidation.[Pubmed]
|
|
| Peroxisomes as novel players in cell calcium homeostasis.[Pubmed]
|
|
| The sterol carrier protein SCP-x/pro-SCP-2 gene has transcriptional activity and regulates the Alzheimer disease gamma-secretase.[Pubmed]
|
|
| The N-terminal half of the peroxisomal cycling receptor Pex5p is a natively unfolded domain.[Pubmed]
|
|
| Peroxisomes: flexible and dynamic organelles.[Pubmed]
|
|
| Targeted fluorescent probes in peroxisome function.[Pubmed]
|
|
| Co-expression of mutated and normal adrenoleukodystrophy protein reduces protein function: implications for gene therapy of X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Lipid metabolism in peroxisomes in relation to human disease.[Pubmed]
|
|
| Peroxisomes in adrenal steroidogenesis.[Pubmed]
|
|
| On the molecular etiology of decreased arachidonic (20:4n-6), docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids in Zellweger syndrome and other peroxisomal disorders.[Pubmed]
|
|
| Immunolocalization of a 43 kDa peroxisomal membrane protein in the liver of patients with generalized peroxisomal disorders.[Pubmed]
|
|
| Adrenoleukodystrophy and other peroxisomal diseases.[Pubmed]
|
|
| Standardization of complementation grouping of peroxisome-deficient disorders and the second Zellweger patient with peroxisomal assembly factor-1 (PAF-1) defect.[Pubmed]
|
|
| Phytanic acid alpha-oxidation and complementation analysis of classical Refsum and peroxisomal disorders.[Pubmed]
|
|
| Peroxisomal integral membrane proteins in control and Zellweger fibroblasts.[Pubmed]
|
|
| A new self-assembled peroxisomal vesicle required for efficient resealing of the plasma membrane.[Pubmed]
|
|
| Peroxisome is a reservoir of intracellular calcium.[Pubmed]
|
|
| Functional and molecular characterization of a glycosomal PPi-dependent enzyme in trypanosomatids: pyruvate, phosphate dikinase.[Pubmed]
|
|
| Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates.[Pubmed]
|
|
| Sterol carrier protein X (SCPx) is a peroxisomal branched-chain beta-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes.[Pubmed]
|
|
| Tissue-specific distribution of a peroxisomal 46-kDa protein related to the 58-kDa protein (sterol carrier protein x; sterol carrier protein 2/3-oxoacyl-CoA thiolase).[Pubmed]
|
|
| Type-II 3-oxoacyl-CoA thiolase of the nematode Caenorhabditis elegans is located in peroxisomes, highly expressed during larval stages and induced by clofibrate.[Pubmed]
|
|
| Thiolase involved in bile acid formation.[Pubmed]
|
|
| Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.[Pubmed]
|
|
| Peroxisomal localization of sulfite oxidase separates it from chloroplast-based sulfur assimilation.[Pubmed]
|
|
| The crystal structure of plant sulfite oxidase provides insights into sulfite oxidation in plants and animals.[Pubmed]
|
|
| Identification and biochemical characterization of Arabidopsis thaliana sulfite oxidase. A new player in plant sulfur metabolism.[Pubmed]
|
|
| Rose bengal-induced photodamage to subcellular membranes and enzymes.[Pubmed]
|
|
| A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism.[Pubmed]
|
|
| Dehydrogenases of the pentose phosphate pathway in rat liver peroxisomes.[Pubmed]
|
|
| Phytol and peroxisome proliferation.[Pubmed]
|
|
| On the synthesis and incorporation of catalase and urate oxidase into the peroxisomes of mouse liver.[Pubmed]
|
|
| Preparation of peroxisomes from mouse liver by rate-zonal centrifugation.[Pubmed]
|
|
| Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes.[Pubmed]
|
|
| Purine nucleotide catabolism in rat liver. Certain preliminary aspects of uricase reaction.[Pubmed]
|
|
| Characterization of the degradation of recombinant rat urate oxidase in tetracycline controlled gene expression cells.[Pubmed]
|
|
| Immunocytochemical localization of a urate oxidase immunoreactive protein in the plasma membranes and membranes of the secretory/endocytic compartments of digestive gland cells of the mussel Mytilus galloprovincialis.[Pubmed]
|
|
| Application of in situ hybridization, cytochemical and immunocytochemical techniques for the investigation of peroxisomes. A review including novel data. Robert Feulgen Prize Lecture 1997.[Pubmed]
|
|
| Iodixanol (Optiprep), an improved density gradient medium for the iso-osmotic isolation of rat liver peroxisomes.[Pubmed]
|
|
| Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel.[Pubmed]
|
|
| Estimation of dolichol and cholesterol synthesis in microsomes and peroxisomes isolated from rat liver.[Pubmed]
|
|
| Rates of beta-oxidation of fatty acids of various chain lengths and degrees of unsaturation in highly purified peroxisomes isolated from rat liver.[Pubmed]
|
|
| Uric acid degrading enzymes, urate oxidase and allantoinase, are associated with different subcellular organelles in frog liver and kidney.[Pubmed]
|
|
| Localization of uric acid oxidase activity in core and matrix of peroxisomes as detected in unfixed cryostat sections of rat liver.[Pubmed]
|
|
| Rat urate oxidase produced by recombinant baculovirus expression: formation of peroxisome crystalloid core-like structures.[Pubmed]
|
|
| Glucocorticoid regulation of rat liver urate oxidase.[Pubmed]
|
|
| Studies on peroxisomal membranes.[Pubmed]
|
|
| Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation.[Pubmed]
|
|
| Morphological and functional modifications of rat liver peroxisomal subpopulations during cold exposure.[Pubmed]
|
|
| Cloning and sequence analysis of cDNA for rat liver uricase.[Pubmed]
|
|
| Localization of urate oxidase in the crystalline cores of rat liver peroxisomes by immunocytochemistry and immunoblotting.[Pubmed]
|
|
| Effect of choline-deficiency and methotrexate administration on peroxisomal beta-oxidation, palmitoyl-CoA hydrolase activity and the glutathione content in rat liver.[Pubmed]
|
|
| Immunocytochemical localization of urate oxidase, fatty acyl-CoA oxidase, and catalase in bovine kidney peroxisomes.[Pubmed]
|
|
| Localization of xanthine oxidase in crystalline cores of peroxisomes. A cytochemical and biochemical study.[Pubmed]
|
|
| Biogenesis of peroxisomes in regenerating rat liver. I. Sequential changes of catalase and urate oxidase detected by ultrastructural cytochemistry.[Pubmed]
|
|
| Source of the hepatic microsomal trans-2-enoyl CoA hydratase bifunctional protein: endoplasmic reticulum or peroxisomes.[Pubmed]
|
|
| Insoluble uricase in liver peroxisomes of Old World monkeys.[Pubmed]
|
|
| Localization of pipecolic acid metabolism in rat liver peroxisomes: probable explanation for hyperpipecolataemia in Zellweger syndrome.[Pubmed]
|
|
| Influence of cyclosporin A treatment on intracellular membranes of hepatocytes.[Pubmed]
|
|
| Formation of chenodeoxycholic acid from 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes.[Pubmed]
|
|
| Isolation and characterization of peroxisomes from the renal cortex of beef, sheep, and cat.[Pubmed]
|
|
| Ultrastructural cytochemical localization of uricase in peroxisomes of rat liver.[Pubmed]
|
|
| Amphibian allantoinase. Molecular cloning, tissue distribution, and functional expression.[Pubmed]
|
|
| Peroxisomal localization and activation by bivalent metal ions of ureidoglycolate lyase, the enzyme involved in urate degradation in Candida tropicalis.[Pubmed]
|
|
| Human hepatic peroxisomes with crystalloid cores associated with urate oxidase activity.[Pubmed]
|
|
| Induction and de novo synthesis of uricase, a nitrogen-regulated enzyme in Neurospora crassa.[Pubmed]
|
|
| The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p.[Pubmed]
|
|
| Ultrastructural localization of xanthine oxidoreductase activity in isolated rat liver cells.[Pubmed]
|
|
| Xanthine dehydrogenase is transported to the Drosophila eye.[Pubmed]
|
|
| Subcellular localization of xanthine oxidase in rat hepatocytes: high-resolution immunoelectron microscopic study combined with biochemical analysis.[Pubmed]
|
|
| Identification of superoxide dismutase in rat liver peroxisomes.[Pubmed]
|
|
| Cytochemical studies of hydrogen peroxide generation in postischemic hepatocytes.[Pubmed]
|
|
| Polarographic assay and intracellular distribution of superoxide dismutase in rat liver.[Pubmed]
|
|
| Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory.[Pubmed]
|
|
| Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.[Pubmed]
|
|
| Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice.[Pubmed]
|
|
| Dietary single cell protein reduces fatty liver in obese Zucker rats.[Pubmed]
|
|
| On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedioic acid (3-thiadicarboxylic acid) in normolipidemic rats.[Pubmed]
|
|
| Lpx1p is a peroxisomal lipase required for normal peroxisome morphology.[Pubmed]
|
|
| Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function?[Pubmed]
|
|
| Metabolic engineering of Saccharomyces cerevisiae for production of novel lipid compounds.[Pubmed]
|
|
| In-vitro differentiation study on isolated human mesenchymal stem cells.[Pubmed]
|
|
| High-density lipoproteins: multifunctional vanguards of the cardiovascular system.[Pubmed]
|
|
| Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression.[Pubmed]
|
|
| Genetic and ultrastructural demonstration of strong reversibility in human mesenchymal stem cell.[Pubmed]
|
|
| Hydroxyeicosatetraenoic acid metabolism in cultured human skin fibroblasts. Evidence for peroxisomal beta-oxidation.[Pubmed]
|
|
| Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations.[Pubmed]
|
|
| ABCD1 translation-initiator mutation demonstrates genotype-phenotype correlation for AMN.[Pubmed]
|
|
| Altered expression of ALDP in X-linked adrenoleukodystrophy.[Pubmed]
|
|
| The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein.[Pubmed]
|
|
| Transduced CD34+ cells from adrenoleukodystrophy patients with HIV-derived vector mediate long-term engraftment of NOD/SCID mice.[Pubmed]
|
|
| Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy.[Pubmed]
|
|
| X-linked adrenoleukodystrophy enigma: how does the ALD peroxisomal transporter mutation affect CNS glia?[Pubmed]
|
|
| Structure and location of the murine adrenoleukodystrophy gene.[Pubmed]
|
|
| Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy.[Pubmed]
|
|
| Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy.[Pubmed]
|
|
| A novel cell model to study the function of the adrenoleukodystrophy-related protein.[Pubmed]
|
|
| ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1).[Pubmed]
|
|
| Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes.[Pubmed]
|
|
| A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.[Pubmed]
|
|
| Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein.[Pubmed]
|
|
| Restoration of peroxisome biogenesis in a peroxisome-deficient mammalian cell line by expression of either the 35 kDa or the 70 kDa peroxisomal membrane proteins.[Pubmed]
|
|
| Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome.[Pubmed]
|
|
| Mouse liver PMP70 and ALDP: homomeric interactions prevail in vivo.[Pubmed]
|
|
| Nucleotide-induced conformational changes of PMP70, an ATP binding cassette transporter on rat liver peroxisomal membranes.[Pubmed]
|
|
| Characterization of the 70-kDa peroxisomal membrane protein, an ATP binding cassette transporter.[Pubmed]
|
|
| Immuno-isolation of highly purified peroxisomes using magnetic beads and continuous immunomagnetic sorting.[Pubmed]
|
|
| Immunocytochemical localization of the 70 kDa peroxisomal membrane protein in connections between peroxisomes in rat liver: support for a reticular organization of peroxisomes maintained by the cytoskeleton.[Pubmed]
|
|
| Sorting of the 70-kDa peroxisomal membrane protein into rat liver peroxisomes in vitro.[Pubmed]
|
|
| Immunoelectron microscopic evidence for organ differences in the composition of peroxisome-specific membrane polypeptides among three rat organs: liver, kidney, and small intestine.[Pubmed]
|
|
| Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Alteration in copy numbers of genes as a mechanism for acquired drug resistance.[Pubmed]
|
|
| Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.[Pubmed]
|
|
| 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins.[Pubmed]
|
|
| The mouse gene encoding the peroxisomal membrane protein 1-like protein (PXMP1-L): cDNA cloning, genomic organization and comparative expression studies.[Pubmed]
|
|
| Two small protein families, DYNAMIN-RELATED PROTEIN3 and FISSION1, are required for peroxisome fission in Arabidopsis.[Pubmed]
|
|
| Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae.[Pubmed]
|
|
| Peroxisome fission in Hansenula polymorpha requires Mdv1 and Fis1, two proteins also involved in mitochondrial fission.[Pubmed]
|
|
| Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae.[Pubmed]
|
|
| The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.[Pubmed]
|
|
| First identification of a 2-ketoglutarate/isocitrate transport system in mammalian peroxisomes and its characterization.[Pubmed]
|
|
| Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy.[Pubmed]
|
|
| Characterization of the adrenoleukodystrophy-related (ALDR, ABCD2) gene promoter: inductibility by retinoic acid and forskolin.[Pubmed]
|
|
| Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy.[Pubmed]
|
|
| Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.[Pubmed]
|
|
| Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator.[Pubmed]
|
|
| ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat.[Pubmed]
|
|
| Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.[Pubmed]
|
|
| Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999.[Pubmed]
|
|
| Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling.[Pubmed]
|
|
| The putative peroxisomal gene Pxt1 is exclusively expressed in the testis.[Pubmed]
|
|
| Ccdc33, a predominantly testis-expressed gene, encodes a putative peroxisomal protein.[Pubmed]
|
|
| Identification, subcellular localization, biochemical properties and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase.[Pubmed]
|
|
| Sorting of phosphoglucomutase to glycosomes in Trypanosoma cruzi is mediated by an internal domain.[Pubmed]
|
|
| Identification of PEX33, a novel component of the peroxisomal docking complex in the filamentous fungus Neurospora crassa.[Pubmed]
|
|
| A single gel for determining genetic variants of equine erythrocyte carbonic anhydrase (CA) and catalase (Cat).[Pubmed]
|
|
| Peroxisomal localization of the proopiomelanocortin-derived peptides beta-lipotropin and beta-endorphin.[Pubmed]
|
|