Protein family catalogue

6-PGL 6-Phosphogluconolactonase
6-PGLDH 6-Phosphogluconate dehydrogenase (decarboxylating)
ABCD ATP-binding cassette sub-family D
ACAA1 3-Ketoacyl-CoA thiolase, peroxisomal precursor (EC (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase).
ACAD Acyl-Coenzyme A dehydrogenase family
ACBD5 Acyl-Coenzyme A binding domain containing 5
ACL Encodes a peroxisomal protein with acetyl-CoA synthetase activity that is responsible for the activation of acetate for entry into the glyoxylate cycle.
ACOX Acyl-coenzyme A oxidase , peroxisomal (EC
AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase).
AGXT Serine--pyruvate aminotransferase (EC (SPT) (Alanine-- glyoxylate aminotransferase) (EC (AGT).
AK Adenylate kinase
ALDH3A2 Aldehyde dehydrogenase 3A2
AMACR Alpha-methylacyl-CoA racemase (EC (2-methylacyl-CoA racemase).
ANT Peroxisomal adenine nucleotide transporter that includes the peroxisomal membrane protein PMP34 (Solute carrier family 25 member 17).
APX Encodes a putative peroxisomal ascorbate peroxidase that scavenges H2O2 into peroxisomes and prevents oxidative damage.
ATG11 Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation.
ATG2 Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking.
BAAT Bile acid Coenzyme A: amino acid N-acyltransferase
CAT Catalase (EC
CCDC33 Coiled-coil domain containing 33
CHY 3-Hydroxyisobutyryl-coenzyme A hydrolase / CoA-thioester hydrolase (CHY1)
CPK A calcium-dependent protein kinase that can phosphorylate phenylalanine ammonia lyase (PAL), a key enzyme in pathogen defense.
CRAT Carnitine O-acetyltransferase (EC (Carnitine acetylase) (CAT) (Carnitine acetyltransferase) (CrAT).
CROT Peroxisomal carnitine O-octanoyltransferase (EC (COT).
CS Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle.
DAO D-amino-acid oxidase (EC (DAMOX) (DAO) (DAAO).
DDO D-aspartate oxidase (EC (DASOX) (DDO).
DHRS4 Dehydrogenase/reductase SDR family (NADPH- dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) .
DJP1 DnaJ (Hsp40) homolog, subfamily C, member 10.
DNM Dynamin 1-like protein (EC (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV)
ECH Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1)
EHHADH Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC; 3,2-trans-enoyl-CoA isomerase (EC; 3-hydroxyacyl-CoA dehydrogenase (EC].
EPHX2 Epoxide hydrolase 2 (EC (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase)
FACL Acyl-CoA synthetase long-chain family.
FAR Fatty acyl CoA reductase that reduces fatty acids to fatty alcohols. Male sterility domain containing.
FBPA Fructose-bisphosphate aldolase, glycosomal.
FH Fumarate hydratase class I.
FIS1 Mitochondrial and peroxisomal protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division.
FNDC5 Fibronectin type III domain containing 5
FR NADH-dependent fumarate reductase.
G6PDH Glucose-6-phosphate 1-dehydrogenase.
G6PI Glucose-6-phosphate isomerase, glycosomal.
GAPDH Glyceraldehyde 3-phosphate dehydrogenase.
GGT A glyoxylate aminotransferase protein localized to the peroxisome and thought to be involved in photorespiration/ metabolic salvage pathway.
GK Glycerol kinase glycosomal
GNPAT Dihydroxyacetone phosphate acyltransferase (EC (DHAP-AT) (DAP-AT) (Glycerone-phosphate O-acyltransferase) (Acyl- CoA:dihydroxyacetonephosphateacyltransferase).
GOT Cytosolic aspartate aminotransferase, involved in nitrogen metabolism.
GPD Glycerol-3-phosphate dehydrogenase
GPK Glyoxysomal protein kinase
GSTK1 Glutathione S-transferase kappa 1 (EC (GST 13-13) (Glutathione S-transferase subunit 13) (GST class-kappa) (GSTK1-1) .
GTO Omega-class glutathione transferase.
HAO Hydroxyacid oxidase. ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long- chain L-2-hydroxy acid oxidase).
HK Hexokinase.
HMGCL Hydroxymethylglutaryl-CoA lyase, (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
HPCL2 2-Hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).
HPR Glycerate dehydrogenase / NADH-dependent hydroxypyruvate reductase
HSD17B4 Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.-); 3- hydroxyacyl-CoA dehydrogenase (EC].
HXGPRT Hypoxanthine-guanine phosphoribosyltransferase.
I5PDH Inosine-5-monophosphate dehydrogenase.
IDE Insulin-degrading enzyme (EC (Insulysin) (Insulinase) (Insulin protease).
IDH Isocitrate dehydrogenase [NADP] (EC (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).
IDI Isopentenyl-diphosphate Delta-isomerase 1 (EC (IPP isomerase 1) (Isopentenyl pyrophosphate isomerase 1) (IPPI1).
INOS Nitric oxide synthase, inducible (EC (NOS type II) (Inducible NOS) (iNOS).
INP1 Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance.
LONP Peroxisomal lon protease
LYS1 Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway.
LYS4 Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway.
MDAR Encodes a peroxisome membrane-bound monodehydroascorbate reductase, involved in the ascorbate-glutathione cycle which removes toxic H2O2.
MDH Malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle.
MLS Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression.
MLYCD Malonyl-CoA decarboxylase, (EC (MCD).
MOSC2 Fe-S protein with 1 predicted TMD that contains a MOSC N-terminal ? barrel domain and was found to be localized in the inner mitochondrial
MPV17 MPV17-Domain bearing proteins
MVK Mevalonate kinase (EC (MK).
MYA2 Myosin heavy chain (MYA2)
NUDT12 Peroxisomal NADH pyrophosphatase NUDT12 (EC (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).
NUDT19 Nudix (nucleoside diphosphate linked moiety X)-type motif 19.
NUDT7 Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7).
OPDC-PRT Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase
OPR 12-Oxophytodienoate reductase 3 (EC (12-oxophytodienoate-10,11-reductase 3) (OPDA-reductase 3) (Delayed dehiscence 1) (AtOPR3)
PAOX Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC (Polyamine oxidase).
PDCR Peroxisomal 2,4-dienoyl-CoA reductase (EC (2,4-dienoyl-CoA reductase 2) (pDCR).
PECR Peroxisomal trans-2-enoyl-CoA reductase (EC (TERP) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP).
PEN2 Encodes a glycosyl hydrolase that localizes to peroxisomes and acts as a component of an inducible preinvasion resistance mechanism.
PEPCK Glycosomal phosphoenolpyruvate carboxykinase
PEX1 Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).
PEX10 Peroxisome assembly protein 10 (Peroxin-10) (RING finger protein 69).
PEX11 Peroxisomal membrane protein 11 (Peroxin-11) (Peroxisomal biogenesis factor 11) .
PEX12 Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).
PEX13 Peroxisomal membrane protein PEX13 (Peroxin-13).
PEX14 Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).
PEX15 Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly.
PEX16 Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16).
PEX17 Peroxisomal membrane protein component of the peroxisomal translocation machinery, required for peroxisome biogenesis, binds Pex14p.
PEX18-21 Part of a two-member peroxin family (Pex18p and Pex21p) specifically required for peroxisomal targeting of the Pex7p peroxisomal signal recognition factor and PTS2 peroxisomal matrix proteins.
PEX19 Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (33 kDa housekeeping protein).
PEX2 Peroxisomal membrane protein 2. Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (35 kDa peroxisomal membrane protein) (RING finger protein 72).
PEX20 Peroxisomal membrane protein 20
PEX22 Peroxisomal membrane protein 20. Peroxisomal membrane protein required for import of peroxisomal proteins.
PEX23 Peroxisomal membrane protein 23
PEX24 Peroxisomal membrane protein 24
PEX25-27 Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number.
PEX26 Peroxisomal membran protein 26. Peroxisome assembly protein 26 (Peroxin-26). [Source:Uniprot/SWISSPROT;Acc:Q7Z412]
PEX3 Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3).
PEX33 Peroxisomal membrane protein PEX13, Peroxin-13.
PEX4 Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis.
PEX5 Peroxisome membrane protein 5 and PEX5-related protein.
PEX6 Peroxisome membrane protein. Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).
PEX7 Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).
PEX8 Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5.
PFK 6-Phospho-1-fructokinase.
PHYH Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase).
PIPOX Peroxisomal sarcosine oxidase (EC (PSO) (L-pipecolate oxidase) (EC (L-pipecolic acid oxidase).
PMP52 Integral membrane protein of 52 kDa with 5 predicted TMDs
PMVK Phosphomevalonate kinase (EC (PMKase).
PNC1 Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction.
POMC pro-opiomelanocortin preproprotein.
PRDX1 Peroxiredoxin 1 (EC (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Proliferation-associated protein PAG) (Natural killer cell enhancing factor A) (NKEF-A).
PRDX5 Peroxiredoxin 5
PTE1 Peroxisomal acyl-coenzyme A thioester hydrolase 1 (EC (Peroxisomal long-chain acyl-coA thioesterase 1) (HIV-Nef associated acyl coA thioesterase) (Thioesterase II) (hTE) (hACTEIII) (hACTE-III) (PTE-2).
PTE2 Peroxisomal acyl-coenzyme A thioester hydrolase 2a (EC (Peroxisomal long-chain acyl-coA thioesterase 2) (ZAP128) (CTE-Ia).
PXMP2 Peroxisomal membrane protein (PMP22) is a major component of peroxisomal membranes. PMP22 seems to be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane.
PXMP4 Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein).
PXT1 Peroxisomal, testis specific 1
PYR-PDK Pyruvate phosphate dikinase.
RHO1 Rho-related GTP-binding protein RhoC (H9).
SCPX Sterol carrier protein 2 (SCP-2), Sterol carrier protein X (SCP-X) (SCPX).
SERHL Serine hydrolase-like protein 2 (EC 3.1.-.-).
SHBP sedoheptulose-1,7-bisphosphatase
SLC22A21 Organic cation/carnitine transporter 2 (Solute carrier family 22 member 5) (High-affinity sodium-dependent carnitine cotransporter).
SOD1 Superoxide dismutase 1
SOD2 Superoxide dismutase 2.
SOX2 Sulfite oxidase. Oxidoreductase molybdopterin binding domain.
STR3 Cystathionine beta-lyase, converts cystathionine into homocysteine.
TPI Triosephosphate isomerase.
TPN Tryparedoxin
TPX Tryparedoxin peroxidase
TR Trypanothione reductase.
TRIM37 Tripartite motif protein 37 (Mulibrey nanism protein).
UDPgal-epi UDP-galactose 4-epimerase.
UGP UDP Glucose pyrophosphoylase
UOX Urate oxidase.
VLACS Solute carrier family 27 (fatty acid transporter).
VPS1 GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization. Involved in regulating peroxisome biogenesis.
XDH Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC (XD); Xanthine oxidase (EC (XO) (Xanthine oxidoreductase)].
XPRT Hypoxanthine-guanine phosphoribosyltransferase.
YOR084W Putative lipase of the peroxisomal matrix.
ZADH2 zinc binding alcohol dehydrogenase, domain containing 2