PEX5 by Pubmed references

2009 Melanie Lingard Proc. Natl. Acad. Sci. U.S.A. Peroxisome-associated matrix protein degradation in Arabidopsis.[Pubmed]
2009 Emilie Verplaetse Biochim. Biophys. Acta Identification, characterization and essentiality of the unusual peroxin 13 from Trypanosoma brucei.[Pubmed]
2009 Kumiko Shiozawa J. Biol. Chem. Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering.[Pubmed]
2009 Christian Neufeld EMBO J. Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.[Pubmed]
2009 Janet Ebberink Hum. Mutat. Genotype-phenotype correlation in PEX5-deficient peroxisome biogenesis defective cell lines.[Pubmed]
2008 Simon Goepfert Plant J. Peroxisomal Delta(3),Delta(2)-enoyl CoA isomerases and evolution of cytosolic paralogues in embryophytes.[Pubmed]
2008 Parthasarathy Sampathkumar J. Mol. Biol. Structural insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.[Pubmed]
2008 Katarzyna Piekarska Microbiology (Reading, Engl.) The activity of the glyoxylate cycle in peroxisomes of Candida albicans depends on a functional beta-oxidation pathway: evidence for reduced metabolite transport across the peroxisomal membrane.[Pubmed]
2008 Sebastian Grou J. Biol. Chem. Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.[Pubmed]
2008 Leen Hulshagen J. Neurosci. Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration.[Pubmed]
2008 Normand Cyr J. Biol. Chem. Leishmania donovani peroxin 14 undergoes a marked conformational change following association with peroxin 5.[Pubmed]
2008 Armando Pilar Mol. Biochem. Parasitol. Interaction of Leishmania PTS2 receptor peroxin 7 with the glycosomal protein import machinery.[Pubmed]
2008 Kamran Ghaedi Cell Biochem. Funct. Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent.[Pubmed]
2007 Kazumasa Nito Plant Cell Physiol. Functional classification of Arabidopsis peroxisome biogenesis factors proposed from analyses of knockdown mutants.[Pubmed]
2007 Jae-Yean Lee Mol. Cells Molecular and functional characterization of monocot-specific Pex5p splicing variants, using OsPex5pL and OsPex5pS from rice (Oryza sativa).[Pubmed]
2007 Nathalie Galland Biochim. Biophys. Acta Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei.[Pubmed]
2007 Chris Williams J. Biol. Chem. A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.[Pubmed]
2007 Fouzi Platta J. Cell Biol. Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling.[Pubmed]
2007 Sashko Cooper Dev. Dyn. Peroxisome biogenesis occurs in late dorsal-anterior structures in the development of Xenopus laevis.[Pubmed]
2007 Corinna Kassmann Nat. Genet. Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.[Pubmed]
2007 Olga Krysko J. Neurosci. Res. Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver.[Pubmed]
2006 Satoru Mukai J. Biol. Chem. Molecular mechanisms of import of peroxisome-targeting signal type 2 (PTS2) proteins by PTS2 receptor Pex7p and PTS1 receptor Pex5pL.[Pubmed]
2006 Cécile Brocard Biochim. Biophys. Acta Peroxisome targeting signal 1: is it really a simple tripeptide?[Pubmed]
2006 Shoji Mano Plant J. The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes.[Pubmed]
2006 Jae-Yean Lee Plant J. Cloning of two splice variants of the rice PTS1 receptor, OsPex5pL and OsPex5pS, and their functional characterization using pex5-deficient yeast and Arabidopsis.[Pubmed]
2006 Matthias Stanley Biochim. Biophys. Acta Dynamic architecture of the peroxisomal import receptor Pex5p.[Pubmed]
2006 Chris Williams Biochim. Biophys. Acta Pex13p: docking or cargo handling protein?[Pubmed]
2006 Daniela Kerssen J. Biol. Chem. Membrane association of the cycling peroxisome import receptor Pex5p.[Pubmed]
2006 Derk Binns J. Cell Biol. An intimate collaboration between peroxisomes and lipid bodies.[Pubmed]
2005 Chris Williams FEBS Lett. Saccharomyces cerevisiae Pex14p contains two independent Pex5p binding sites, which are both essential for PTS1 protein import.[Pubmed]
2005 Non Miyata Mol. Cell. Biol. Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export.[Pubmed]
2005 Annette Schell-Steven Mol. Cell. Biol. Identification of a novel, intraperoxisomal pex14-binding site in pex13: association of pex13 with the docking complex is essential for peroxisomal matrix protein import.[Pubmed]
2005 Kerstin Kiel J. Biol. Chem. Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import.[Pubmed]
2005 Stefania Bonsegna Arch. Biochem. Biophys. AtLACS7 interacts with the TPR domains of the PTS1 receptor PEX5.[Pubmed]
2005 Makoto Hayashi J. Biol. Chem. Differential contribution of two peroxisomal protein receptors to the maintenance of peroxisomal functions in Arabidopsis.[Pubmed]
2005 Bonnie Woodward Mol. Biol. Cell The Arabidopsis peroxisomal targeting signal type 2 receptor PEX7 is necessary for peroxisome function and dependent on PEX5.[Pubmed]
2005 Armando Madrid Biochem. J. Peroxin 5-peroxin 14 association in the protozoan Leishmania donovani involves a novel protein-protein interaction motif.[Pubmed]
2005 Karsten Niederhoff J. Biol. Chem. Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites.[Pubmed]
2004 Georg Neuberger Genome Biol. Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins.[Pubmed]
2004 João Azevedo Cell Biochem. Biophys. Protein translocation across the peroxisomal membrane.[Pubmed]
2004 Antje Schäfer Mol. Cell. Biol. Functional similarity between the peroxisomal PTS2 receptor binding protein Pex18p and the N-terminal half of the PTS1 receptor Pex5p.[Pubmed]
2004 Yuko Ogata Anal. Biochem. Automated affinity chromatography measurements of compound mixtures using a lab-on-valve apparatus coupled to electrospray ionization mass spectrometry.[Pubmed]
2004 Bonnie Zolman Proc. Natl. Acad. Sci. U.S.A. An Arabidopsis indole-3-butyric acid-response mutant defective in PEROXIN6, an apparent ATPase implicated in peroxisomal function.[Pubmed]
2004 Myriam Pettus Rapid Commun. Mass Spectrom. Mass spectrometric analysis of ceramide perturbations in brain and fibroblasts of mice and human patients with peroxisomal disorders.[Pubmed]
2003 Eveline Baumgart Microsc. Res. Tech. A review of morphological techniques for detection of peroxisomal (and mitochondrial) proteins and their corresponding mRNAs during ontogenesis in mice: application to the PEX5-knockout mouse with Zellweger syndrome.[Pubmed]
2003 Georg Neuberger J. Mol. Biol. Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence.[Pubmed]
2003 Sietske Hogenboom Mol. Genet. Metab. Cholesterol biosynthesis is not defective in peroxisome biogenesis defective fibroblasts.[Pubmed]
2003 Yuang Huang Biochem. Biophys. Res. Commun. Altered antigenic disposition of peroxisomal urate oxidase in PEX5-defective Chinese hamster ovary cells.[Pubmed]
2003 Gatto Gatto Biochemistry Correlating structure and affinity for PEX5:PTS1 complexes.[Pubmed]
2003 Harper Harper J. Biol. Chem. PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12.[Pubmed]
2003 Silvia Marchesini Appl. Environ. Microbiol. Modification of the monomer composition of polyhydroxyalkanoate synthesized in Saccharomyces cerevisiae expressing variants of the beta-oxidation-associated multifunctional enzyme.[Pubmed]
2003 Jungwoo Choe Biochemistry Analysis of the sequence motifs responsible for the interactions of peroxins 14 and 5, which are involved in glycosome biogenesis in Trypanosoma brucei.[Pubmed]
2003 Silvia Marchesini J. Biol. Chem. Futile cycling of intermediates of fatty acid biosynthesis toward peroxisomal beta-oxidation in Saccharomyces cerevisiae.[Pubmed]
2003 Hanspeter Rottensteiner Eur. J. Biochem. Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE.[Pubmed]
2003 Anneleen Janssen J. Neurosci. Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues.[Pubmed]
2002 Xiaoling Li Mol. Cell. Biol. PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function.[Pubmed]
2002 M Baes J. Neuropathol. Exp. Neurol. The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal beta-oxidation.[Pubmed]
2002 M Baes Genesis Generation of Pex5-loxP mice allowing the conditional elimination of peroxisomes.[Pubmed]
2002 Jukka Kallijärvi Am. J. Hum. Genet. The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder.[Pubmed]
2002 Sietske Hogenboom J. Lipid Res. Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.[Pubmed]
2002 Hidenori Otera Mol. Cell. Biol. Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.[Pubmed]
2002 Marlene Klein J. Biol. Chem. Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.[Pubmed]
2002 Harper Harper J. Biol. Chem. Peroxisomal membrane protein import does not require Pex17p.[Pubmed]
2001 E Baumgart Am. J. Pathol. Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse).[Pubmed]
2001 R Ito Biochem. Biophys. Res. Commun. Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene.[Pubmed]
2001 I Vanhorebeek Biochim. Biophys. Acta Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model.[Pubmed]
2001 J Saidowsky J. Biol. Chem. The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.[Pubmed]
2001 Y Suzuki J. Inherit. Metab. Dis. Clinical, biochemical and genetic aspects and neuronal migration in peroxisome biogenesis disorders.[Pubmed]
2001 A Kumar J. Mol. Biol. An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.[Pubmed]
2001 M Casteels Biochem. Soc. Trans. Further insights into peroxisomal lipid breakdown via alpha- and beta-oxidation.[Pubmed]
2001 S Huyghe Biochem. J. Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse.[Pubmed]
2001 Infante Infante Mol. Genet. Metab. Zellweger syndrome knockout mouse models challenge putative peroxisomal beta-oxidation involvement in docosahexaenoic acid (22:6n-3) biosynthesis.[Pubmed]
2001 G Dodt J. Biol. Chem. Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p.[Pubmed]
2001 L Amery Biochem. J. Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.[Pubmed]
2001 A Gurvitz Mol. Genet. Genomics The tetratricopeptide repeat domains of human, tobacco, and nematode PEX5 proteins are functionally interchangeable with the analogous native domain for peroxisomal import of PTS1-terminated proteins in yeast.[Pubmed]
2000 A Gurvitz Yeast Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes.[Pubmed]
2000 Smith Smith Proc. Natl. Acad. Sci. U.S.A. A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of alpha 2.[Pubmed]
2000 T Matsumura J. Biol. Chem. Disruption of the interaction of the longer isoform of Pex5p, Pex5pL, with Pex7p abolishes peroxisome targeting signal type 2 protein import in mammals. Study with a novel Pex5-impaired Chinese hamster ovary cell mutant.[Pubmed]
2000 H Otera J. Biol. Chem. The mammalian peroxin Pex5pL, the longer isoform of the mobile peroxisome targeting signal (PTS) type 1 transporter, translocates the Pex7p.PTS2 protein complex into peroxisomes via its initial docking site, Pex14p.[Pubmed]
2000 Gatto Gatto Nat. Struct. Biol. Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5.[Pubmed]
2000 M Ito Biochim. Biophys. Acta Rapid isolation and characterization of CHO mutants deficient in peroxisome biogenesis using the peroxisomal forms of fluorescent proteins.[Pubmed]
2000 A Jardim J. Biol. Chem. Peroxisomal targeting signal-1 receptor protein PEX5 from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.[Pubmed]
2000 A Zolman Genetics Genetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classes.[Pubmed]
2000 Gatto Gatto Proteins A proposed model for the PEX5-peroxisomal targeting signal-1 recognition complex.[Pubmed]
2000 Szilard Szilard Biochem. J. Tetratricopeptide repeat domain of Yarrowia lipolytica Pex5p is essential for recognition of the type 1 peroxisomal targeting signal but does not confer full biological activity on Pex5p.[Pubmed]
2000 A Janssen Lab. Invest. Docosahexaenoic acid deficit is not a major pathogenic factor in peroxisome-deficient mice.[Pubmed]
2000 Lee Lee J. Biochem. Identification of a cryptic N-terminal signal in Saccharomyces cerevisiae peroxisomal citrate synthase that functions in both peroxisomal and mitochondrial targeting.[Pubmed]
2000 G Bottger Mol. Biol. Cell Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.[Pubmed]
1999 K Ghaedi Exp. Cell Res. Isolation and characterization of novel peroxisome biogenesis-defective Chinese hamster ovary cell mutants using green fluorescent protein.[Pubmed]
1999 S Kiel Mol. Biochem. Parasitol. Cloning and analysis of the PTS-1 receptor in Trypanosoma brucei.[Pubmed]
1999 M Yamasaki J. Biol. Chem. Formation of peroxisomes from peroxisomal ghosts in a peroxisome-deficient mammalian cell mutant upon complementation by protein microinjection.[Pubmed]
1999 Chang Chang J. Cell Biol. PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.[Pubmed]
1999 N Shimozawa Biochem. Biophys. Res. Commun. Functional heterogeneity of C-terminal peroxisome targeting signal 1 in PEX5-defective patients.[Pubmed]
1999 S Chang J. Cell. Sci. Metabolic control of peroxisome abundance.[Pubmed]
1999 W Schliebs J. Biol. Chem. Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.[Pubmed]
1998 N Braverman Hum. Mol. Genet. An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes.[Pubmed]
1998 F Kragler Proc. Natl. Acad. Sci. U.S.A. Identification and analysis of the plant peroxisomal targeting signal 1 receptor NtPEX5.[Pubmed]
1998 F Navarro-García Yeast Cloning and sequence of a 3.835 kbp DNA fragment containing the HIS4 gene and a fragment of a PEX5-like gene from Candida albicans.[Pubmed]
1998 A Gurvitz Histochem. Cell Biol. Fate and role of peroxisomes during the life cycle of the yeast Saccharomyces cerevisiae: inheritance of peroxisomes during meiosis.[Pubmed]
1998 H Otera Mol. Cell. Biol. Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.[Pubmed]
1998 T Wylin Eur. J. Biochem. Identification and characterization of human PMP34, a protein closely related to the peroxisomal integral membrane protein PMP47 of Candida boidinii.[Pubmed]
1998 J Björkman Genomics Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene.[Pubmed]
1997 T Tsukamoto Biochem. Biophys. Res. Commun. Isolation of a new peroxisome-deficient CHO cell mutant defective in peroxisome targeting signal-1 receptor.[Pubmed]
1997 Titorenko Titorenko Mol. Cell. Biol. Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica.[Pubmed]
1997 M Baes Nat. Genet. A mouse model for Zellweger syndrome.[Pubmed]
1996 G Dodt J. Cell Biol. Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor.[Pubmed]
1996 Purdue Purdue J. Cell Biol. Targeting of human catalase to peroxisomes is dependent upon a novel COOH-terminal peroxisomal targeting sequence.[Pubmed]
1994 C Brocard Biochem. Biophys. Res. Commun. The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL.[Pubmed]
1993 I Franse Proc. Natl. Acad. Sci. U.S.A. PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae.[Pubmed]
0 Mol. Biochem. Parasitol. Peroxisomal targeting protein 14 (PEX14) from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.[Pubmed]