ABC transporters by Pubmed references

YEAR FIRST AUTHOR JOURNAL TITLE
2009 Pedro Brites Brain Plasmalogens participate in very-long-chain fatty acid-induced pathology.[Pubmed]
2009 Stéphane Fourcade Am. J. Physiol. Endocrinol. Metab. A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.[Pubmed]
2009 Yoshinori Kashiwayama Exp. Cell Res. 70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins.[Pubmed]
2009 Daniela Dietrich Mol. Biol. Cell Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series.[Pubmed]
2009 Liu Liu J. Lipid Res. ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat.[Pubmed]
2009 Jaspreet Singh J. Lipid Res. Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.[Pubmed]
2008 Stéphane Fourcade Hum. Mol. Genet. Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.[Pubmed]
2008 M Morita J. Inherit. Metab. Dis. Baicalein 5,6,7-trimethyl ether activates peroxisomal but not mitochondrial fatty acid beta-oxidation.[Pubmed]
2008 Rita Denti Neurochem. Int. RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: a model system to study PMP70 function.[Pubmed]
2008 Lodewijk Visser FASEB J. The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters.[Pubmed]
2008 M Engelen Biochim. Biophys. Acta Cholesterol-deprivation increases mono-unsaturated very long-chain fatty acids in skin fibroblasts from patients with X-linked adrenoleukodystrophy.[Pubmed]
2007 Jyh-Feng Lu Lab. Invest. The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage.[Pubmed]
2007 Stephan Kemp Mol. Genet. Metab. X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism, ABC half-transporters and the complicated route to treatment.[Pubmed]
2007 Anca Nenicu Biol. Reprod. Peroxisomes in human and mouse testis: differential expression of peroxisomal proteins in germ cells and distinct somatic cell types of the testis.[Pubmed]
2007 Yoshinori Kashiwayama J. Biol. Chem. Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein.[Pubmed]
2007 Norimasa Takahashi J. Neurochem. Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations.[Pubmed]
2007 Sally Hooks Biochem. J. The Arabidopsis ALDP protein homologue COMATOSE is instrumental in peroxisomal acetate metabolism.[Pubmed]
2007 F Thevenieau Fungal Genet. Biol. Characterization of Yarrowia lipolytica mutants affected in hydrophobic substrate utilization.[Pubmed]
2007 Rea Rea Plant ATP-binding cassette transporters.[Pubmed]
2007 Lodewijk Visser Biochem. J. Metabolite transport across the peroxisomal membrane.[Pubmed]
2007 Hossein Burke Transl Res Mitochondrial ATP-binding cassette proteins.[Pubmed]
2007 Stephan Wanders Pflugers Arch. The peroxisomal ABC transporter family.[Pubmed]
2006 Fabien Gueugnon Biochem. Biophys. Res. Commun. A novel cell model to study the function of the adrenoleukodystrophy-related protein.[Pubmed]
2006 Johannes Berger Biochim. Biophys. Acta X-linked adrenoleukodystrophy: clinical, biochemical and pathogenetic aspects.[Pubmed]
2006 Masashi Morita Biol. Pharm. Bull. ATP-binding and -hydrolysis activities of ALDP (ABCD1) and ALDRP (ABCD2), human peroxisomal ABC proteins, overexpressed in Sf21 cells.[Pubmed]
2005 Yoshinori Kashiwayama Biochim. Biophys. Acta Role of Pex19p in the targeting of PMP70 to peroxisome.[Pubmed]
2005 K Dunster Clin. Exp. Immunol. Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes.[Pubmed]
2005 Muriel Asheuer Hum. Mol. Genet. Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy.[Pubmed]
2005 Isidre Ferrer Hum. Mol. Genet. Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.[Pubmed]
2005 Catherine Gondcaille J. Cell Biol. Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator.[Pubmed]
2005 Clara Guimarães J. Hum. Genet. Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis.[Pubmed]
2005 Helen Pinfield-Wells Plant J. Sucrose rescues seedling establishment but not germination of Arabidopsis mutants disrupted in peroxisomal fatty acid catabolism.[Pubmed]
2005 Sidney Mak Horm. Res. Novel insertion 496_497insG creating a stop codon D194X in a Chinese family with X-Linked adrenoleukodystrophy.[Pubmed]
2004 Martin Fulda Plant Cell Peroxisomal Acyl-CoA synthetase activity is essential for seedling development in Arabidopsis thaliana.[Pubmed]
2004 Aurora Pujol Hum. Mol. Genet. Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy.[Pubmed]
2004 Kohichiroh Yasui Cancer Res. Alteration in copy numbers of genes as a mechanism for acquired drug resistance.[Pubmed]
2004 Kovacs Kovacs Mol. Cell. Biol. Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model.[Pubmed]
2004 Pedro Guimarães Biochim. Biophys. Acta Mouse liver PMP70 and ALDP: homomeric interactions prevail in vivo.[Pubmed]
2004 Inderjit Singh Brain Res. Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.[Pubmed]
2004 Hiroyuki Shibata J. Biol. Chem. Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins.[Pubmed]
2004 Mark IJlst J. Cell. Sci. The peroxisomal lumen in Saccharomyces cerevisiae is alkaline.[Pubmed]
2004 Charles Peters Blood Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999.[Pubmed]
2003 Stéphanie Boisnard Mol. Microbiol. Overexpression of a human and a fungal ABC transporter similarly suppresses the differentiation defects of a fungal peroxisomal mutant but introduces pleiotropic cellular effects.[Pubmed]
2003 Isao Ilieva Neurol. Res. Age-related changes in peroxisomal membrane protein 70 and superoxide dismutase 1 in transgenic G93A mice.[Pubmed]
2003 Ben Geuze Mol. Biol. Cell Involvement of the endoplasmic reticulum in peroxisome formation.[Pubmed]
2003 Johannes Berger Adv. Exp. Med. Biol. Lessons from knockout mice II: Mouse models for peroxisomal disorders with single protein deficiency.[Pubmed]
2003 Mikinori Kurisu Biochem. Biophys. Res. Commun. Existence of catalase-less peroxisomes in Sf21 insect cells.[Pubmed]
2003 Sonia Benhamida Mol. Ther. Transduced CD34+ cells from adrenoleukodystrophy patients with HIV-derived vector mediate long-term engraftment of NOD/SCID mice.[Pubmed]
2003 J-F McGuinness Mol. Cell. Biol. Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy.[Pubmed]
2003 Pablo Landgraf Eur. J. Cell Biol. Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif.[Pubmed]
2002 Steven Footitt EMBO J. Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP.[Pubmed]
2002 J Gärtner Endocr. Res. Functional characterization of the adrenoleukodystrophy protein (ALDP) and disease pathogenesis.[Pubmed]
2002 Makoto Hayashi Plant Cell Physiol. Ped3p is a peroxisomal ATP-binding cassette transporter that might supply substrates for fatty acid beta-oxidation.[Pubmed]
2002 Tanja Mayerhofer Biochem. Biophys. Res. Commun. Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly.[Pubmed]
2002 Aurora Pujol Hum. Mol. Genet. Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy.[Pubmed]
2002 Kouichi Tanaka J. Biol. Chem. ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1).[Pubmed]
2002 Aritoshi Iida J. Hum. Genet. Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.[Pubmed]
2002 Yoshinori Kashiwayama Biochem. Biophys. Res. Commun. Nucleotide-induced conformational changes of PMP70, an ATP binding cassette transporter on rat liver peroxisomal membranes.[Pubmed]
2002 Nobuyuki Shimozawa Biochem. Biophys. Res. Commun. A novel aberrant splicing mutation of the PEX16 gene in two patients with Zellweger syndrome.[Pubmed]
2002 Noriyo Hashiguchi Mol. Biol. Cell Peroxisomes are formed from complex membrane structures in PEX6-deficient CHO cells upon genetic complementation.[Pubmed]
2002 Deyanira Corzo Am. J. Hum. Genet. Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders.[Pubmed]
2002 Isabelle Weinhofer Hum. Mol. Genet. Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy.[Pubmed]
2001 A Gurvitz J. Biol. Chem. Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11.[Pubmed]
2001 A Gurvitz J. Biol. Chem. Peroxisomal degradation of trans-unsaturated fatty acids in the yeast Saccharomyces cerevisiae.[Pubmed]
2001 S Kemp Hum. Mutat. ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: role in diagnosis and clinical correlations.[Pubmed]
2001 M Biermanns Biochem. Biophys. Res. Commun. Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes.[Pubmed]
2001 P Roerig FEBS Lett. Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters.[Pubmed]
2001 Y Suzuki J. Inherit. Metab. Dis. Clinical, biochemical and genetic aspects and neuronal migration in peroxisome biogenesis disorders.[Pubmed]
2001 T Voorn-Brouwer J. Cell. Sci. Peroxisomal membrane proteins are properly targeted to peroxisomes in the absence of COPI- and COPII-mediated vesicular transport.[Pubmed]
2001 W Kovacs Histochem. Cell Biol. Localization of mRNAs encoding peroxisomal proteins in cell culture by non-radioactive in situ hybridization. Comparison of rat and human hepatoma cells and their responses to two divergent hypolipidemic drugs.[Pubmed]
2001 Clayton Clayton Biochem. Soc. Trans. Clinical consequences of defects in peroxisomal beta-oxidation.[Pubmed]
2000 A Gurvitz Mol. Cell Biol. Res. Commun. Adr1p-dependent regulation of the oleic acid-inducible yeast gene SPS19 encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase.[Pubmed]
2000 A Gurvitz Yeast Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes.[Pubmed]
2000 P Borst Biochim. Biophys. Acta ABC transporters in lipid transport.[Pubmed]
2000 A Pujol Genomics Characterization of the adrenoleukodystrophy-related (ALDR, ABCD2) gene promoter: inductibility by retinoic acid and forskolin.[Pubmed]
2000 C Fujiwara J. Biol. Chem. Catalase-less peroxisomes. Implication in the milder forms of peroxisome biogenesis disorder.[Pubmed]
2000 T Yamada Cell Biochem. Biophys. Very-long-chain fatty acid metabolism in adrenoleukodystrophy protein-deficient mice.[Pubmed]
2000 G Unterrainer Hum. Mol. Genet. Co-expression of mutated and normal adrenoleukodystrophy protein reduces protein function: implications for gene therapy of X-linked adrenoleukodystrophy.[Pubmed]
2000 P Aubourg Glia X-linked adrenoleukodystrophy enigma: how does the ALD peroxisomal transporter mutation affect CNS glia?[Pubmed]
1999 Braiterman Braiterman Mol. Genet. Metab. Peroxisomal very long chain fatty acid beta-oxidation activity is determined by the level of adrenodeukodystrophy protein (ALDP) expression.[Pubmed]
1999 H Bauer Biochim. Biophys. Acta Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance.[Pubmed]
1999 J Berger Eur. J. Biochem. The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression.[Pubmed]
1999 A Holzinger Biochem. Biophys. Res. Commun. Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy.[Pubmed]
1999 A Netik Hum. Mol. Genet. Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.[Pubmed]
1999 T Imanaka J. Biol. Chem. Characterization of the 70-kDa peroxisomal membrane protein, an ATP binding cassette transporter.[Pubmed]
1999 M Yamasaki J. Biol. Chem. Formation of peroxisomes from peroxisomal ghosts in a peroxisome-deficient mammalian cell mutant upon complementation by protein microinjection.[Pubmed]
1999 Collins Collins Hum. Mutat. Identification of a common PEX1 mutation in Zellweger syndrome.[Pubmed]
1999 McGuinness McGuinness Arch. Immunol. Ther. Exp. (Warsz.) Cerebral inflammation in X-linked adrenoleukodystrophy.[Pubmed]
1998 S Braiterman Hum. Mol. Genet. Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins.[Pubmed]
1998 A Holzinger FEBS Lett. The mouse gene encoding the peroxisomal membrane protein 1-like protein (PXMP1-L): cDNA cloning, genomic organization and comparative expression studies.[Pubmed]
1998 R Lüers Electrophoresis Immuno-isolation of highly purified peroxisomes using magnetic beads and continuous immunomagnetic sorting.[Pubmed]
1998 S Kemp Nat. Med. Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy.[Pubmed]
1998 J Gärtner Eur. J. Cell Biol. Restoration of PEX2 peroxisome assembly defects by overexpression of PMP70.[Pubmed]
1997 A Holzinger Biochem. Biophys. Res. Commun. Primary structure of human PMP69, a putative peroxisomal ABC-transporter.[Pubmed]
1997 N Shani Hum. Mol. Genet. Identification of a fourth half ABC transporter in the human peroxisomal membrane.[Pubmed]
1997 K Okumoto Nat. Genet. PEX12 encodes an integral membrane protein of peroxisomes.[Pubmed]
1997 K Häyrinen Eur. J. Cell Biol. Immunocytochemical localization of the 70 kDa peroxisomal membrane protein in connections between peroxisomes in rat liver: support for a reticular organization of peroxisomes maintained by the cytoskeleton.[Pubmed]
1996 A Kennedy Genomics Structure and location of the murine adrenoleukodystrophy gene.[Pubmed]
1996 N Shimozawa Pediatr. Res. Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients.[Pubmed]
1996 T Imanaka Ann. N. Y. Acad. Sci. Sorting of the 70-kDa peroxisomal membrane protein into rat liver peroxisomes in vitro.[Pubmed]
1996 T Imanaka J. Biol. Chem. Insertion of the 70-kDa peroxisomal membrane protein into peroxisomal membranes in vivo and in vitro.[Pubmed]
1996 M Contreras Arch. Biochem. Biophys. Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes.[Pubmed]
1996 N Shani Proc. Natl. Acad. Sci. U.S.A. A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.[Pubmed]
1996 B Hettema EMBO J. The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.[Pubmed]
1996 N Shani J. Biol. Chem. Characterization and analysis of conserved motifs in a peroxisomal ATP-binding cassette transporter.[Pubmed]
1996 G Lombard-Platet Proc. Natl. Acad. Sci. U.S.A. A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.[Pubmed]
1995 F Watkins Am. J. Hum. Genet. Altered expression of ALDP in X-linked adrenoleukodystrophy.[Pubmed]
1995 N Shani Proc. Natl. Acad. Sci. U.S.A. PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.[Pubmed]
1994 J Gärtner J. Inherit. Metab. Dis. Restoration of peroxisome biogenesis in a peroxisome-deficient mammalian cell line by expression of either the 35 kDa or the 70 kDa peroxisomal membrane proteins.[Pubmed]
1994 P Aubourg Curr. Opin. Genet. Dev. Adrenoleukodystrophy and other peroxisomal diseases.[Pubmed]
1994 J Mosser Hum. Mol. Genet. The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein.[Pubmed]
1993 J Gärtner Semin. Cell Biol. The 70 kDa peroxisomal membrane protein: an ATP-binding cassette transporter protein involved in peroxisome biogenesis.[Pubmed]
1993 J Mosser Nature Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters.[Pubmed]
1992 J Gärtner Nat. Genet. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome.[Pubmed]
1991 N Usuda J. Histochem. Cytochem. Immunoelectron microscopic evidence for organ differences in the composition of peroxisome-specific membrane polypeptides among three rat organs: liver, kidney, and small intestine.[Pubmed]
0 Mol. Membr. Biol. Trypanosoma brucei glycosomal ABC transporters: identification and membrane targeting.[Pubmed]
0 Mol. Genet. Metab. X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases.[Pubmed]
0 Neurology ABCD1 translation-initiator mutation demonstrates genotype-phenotype correlation for AMN.[Pubmed]