Gene : PEX16

Symbol :	PEX16
Name/description :	peroxisomal biogenesis factor 16
Synonyms :
Organism :	Homo sapiens
Peroxisomal Localization :	GO: peroxisome South South, et al.1999. J. Cell Biol. Masanori Honsho, et al.2002. J. Biol. Chem. Christopher Brocard, et al.2005. Traffic Uwe Kim, et al.2006. J. Cell Biol. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX16
Protein consensus sequence :	PEX19=0.044; start position=120; end position=129; MEKLRLLGLRYQEYVTRHPAATAQLETAVRGFSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALVQLAKAVLRMLLLLWFKAGLQTSPPIVPLDRETQAQPPDGDHSPGNHEQSYVGKRSNRVVRTLQNTPSLHSRHWGAPQQREGRQQQHHEELSATPTPLGLQETIAEFLYIARPLLHLLSLGLWGQRSWKPWLLAGVVDVTSLSLLSDRKGLTRRERRELRRRTILLLYYLLRSPFYDRFSEARILFLLQLLADHVPGVGLVTTSQRAASPCLPARPHTQPWSPPAFLPGHP
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome membrane assembly
Disease(s) :	Zellweger syndrome
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL SNPs (NCBI) Intron/Exon (Ace View: NCBI) Gene Expression (UCSC) Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Christopher Brocard, et al.2005. Traffic Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis. Hiroyuki Shibata, et al.2004. J. Biol. Chem. Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins. Masanori Honsho, et al.2002. J. Biol. Chem. The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly. T Voorn-Brouwer, et al.2001. J. Cell. Sci. Peroxisomal membrane proteins are properly targeted to peroxisomes in the absence of COPI- and COPII-mediated vesicular transport. South South, et al.1999. J. Cell Biol. Peroxisome synthesis in the absence of preexisting peroxisomes.