Disease : Zellweger syndrome

Name : Zellweger syndrome
Description : Autosomal recessive lethal disorder caused by mutations in different genes involved in peroxisome biogenesis. Symptoms: organs affected are liver, kidney and brain of infants. Polymicrogyria, enlarged liver, high levels of iron and copper in blood, and vision disturbances are among the major clinical manifestations.
Gene(s) :
Localization(s) :
  • Cytosol
  • Peroxisomal membrane
  • Peroxisome
Functional category(ies) :
Links of Interest: