Gene : PEX1

• Homo sapiens

• GO: peroxisome
  • E Reuber, et al.1997. Nat. Genet.
  • S Tamura, et al.2001. Biochem. J.
  • Tam Nguyen, et al.2006. J. Cell. Sci.
  • Shigehiko Tamura, et al.2006. J. Biol. Chem.
• GFP: No experiment found
• Mass Spectrometry: No experiment found
• PeroxisomeDB annotation

• PEX1

PEX19=0.064; start position=544; end position=553;

• Peroxisomal AAA-ATPases
• Peroxisome biogenesis (peroxins)

• Zellweger syndrome
• Neonatal adrenoleukodystrophy
• Infantile Refsum disease

• PTS prediction
• Blastp
• PsiBlast
• Alignment
• Phylogenetic tree [help]
• PhylomeDB

• Gene Summary (NCBI)
• Genome Browser (UCSC)
• Chromosomal Localization (NCBI)
• ENSEMBL
• SNPs (NCBI)
• Intron/Exon (Ace View: NCBI)
• Gene Expression (UCSC)
• Protein Properties (UCSC)
• Conserved Domains (NCBI)
• Orthologue Prediction (NCBI)

• Shigehiko Tamura, et al.2006. J. Biol. Chem. Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p.
• Satomi Furuki, et al.2006. J. Biol. Chem. Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.
• Crane Crane, et al.2005. Hum. Mutat. PEX1 mutations in the Zellweger spectrum of the peroxisome biogenesis disorders.
• Christopher Brocard, et al.2005. Traffic Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis.
• J Barth, et al.2004. Neurology Neuroimaging of peroxisome biogenesis disorders (Zellweger spectrum) with prolonged survival.
• C Walter, et al.2001. Am. J. Hum. Genet. Disorders of peroxisome biogenesis due to mutations in PEX1: phenotypes and PEX1 protein levels.