Gene : PEX14

Symbol :	PEX14
Name/description :	peroxisomal biogenesis factor 14
Synonyms :	NAPP2, Pex14p, MGC12767, dJ734G22.2
Organism :	Homo sapiens
Peroxisomal Localization :	GO: peroxisome Nobuyuki Shimozawa, et al.2004. Hum. Mutat. Christian Neufeld, et al.2009. EMBO J. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX14
Protein consensus sequence :	MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESERD
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome docking
Disease(s) :	Zellweger syndrome
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL SNPs (NCBI) Intron/Exon (Ace View: NCBI) Gene Expression (UCSC) Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Kumiko Shiozawa, et al.2009. J. Biol. Chem. Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering. Christian Neufeld, et al.2009. EMBO J. Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19. Marc Fransen, et al.2004. J. Biol. Chem. Potential role for Pex19p in assembly of PTS-receptor docking complexes. J Saidowsky, et al.2001. J. Biol. Chem. The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14. W Schliebs, et al.1999. J. Biol. Chem. Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.