Name : | Polyamines degradation |
Description : | Polyamines are required for numerous important processes such as wound healing, tissue growth and diferentitaion, and tumor growth. The peroxisomal enzyme PAO plays a ROLE in regulation of intracellular polyamine concentration, acting as a determinant of cellular sensitivity to the antitumor polyamine analogs. N(1)-acetylated polyamines and, in less extension, spermine, are substrates for PAO. |
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