Peroxisome Identification Tool
The peroxisomal proteins: PEX3 , PEX10, PEX12 and PEX19 are peroxisomal molecular markers. Failure to identify the 4 markers unequivocally means absence of the organelle.
Launch the NCBI tblastn to identify the above mentioned markers in your organism of interest.
| PEX3 | BLAST |
| PEX10 | BLAST |
| PEX12 | BLAST |
| PEX19 | BLAST |
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Figure: protein distribution. Distribution among the Eukarya of the selected peroxisomal proteins that lack significant homologies within Bacteria/Archea taxa. Peroxisomal markers (M): Pex3, Pex19, Pex10, and Pex12. Pex26 is restricted to vertebrate, Pxmp4 to Fungi and Metazoa (excluding Insecta). Pex13 is excluded from the photosynthtetic lineage. The amitochondriates Encephalitozoon cuniculi (EC) and Giardia lamblia (GL) have no peroxisomal proteins. The apicomplexa Plasmodium falciparum (PF) and Cryptosporidium parvum (CP) contain mitochondria but no peroxisomes. HS: Homo sapiens, RN: Ratus norvegicus, MM: Mus musculus, TN: Tetraodon nigroviridis, DM: Drosophila melanogaster, AG: Anopheles gambiae, CE: Caenorhabditis elegans, SC: Saccharomyces cerevisiae, SP: Schizosaccharomyces pombe, AT: Arabidopsis thaliana, OS: Oryza sativa, DD: Dictyostelium discoideum, PF: Plasmodium falciparum, GL: Giardia Lamblia, EC: Encephalitozoon cuniculi, CP: Cryptosporidium parvum, CM: Cyanidioschyzon merolae, TP: Thalassiosiria Pseudonana.