Description : |
Transporters that include the ATP Binding Cassette (ABC). All known peroxisomes have at least one ABC transporter, therefore are highly conserved throughout the evolution. For example, in mammals, there are 4 peroxisomal ABC transporters: ABCD1, ABCD2, ABCD3 and ABCD4. Lack of function of ABCD1, or Ald, causes a severe human disease: the X-linked Adrenoleukodystrophy.
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