| PROTEIN FAMILY | DESCRIPTION |
|---|---|
| 6-PGL | 6-Phosphogluconolactonase |
| 6-PGLDH | 6-Phosphogluconate dehydrogenase (decarboxylating) |
| ABCD | ATP-binding cassette sub-family D |
| ACAA1 | 3-Ketoacyl-CoA thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase). |
| ACAD | Acyl-Coenzyme A dehydrogenase family |
| ACBD5 | Acyl-Coenzyme A binding domain containing 5 |
| ACL | Encodes a peroxisomal protein with acetyl-CoA synthetase activity that is responsible for the activation of acetate for entry into the glyoxylate cycle. |
| ACOX | Acyl-coenzyme A oxidase , peroxisomal (EC 1.3.3.6) |
| AGPS | Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase). |
| AGXT | Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT). |
| AK | Adenylate kinase |
| ALDH3A2 | Aldehyde dehydrogenase 3A2 |
| AMACR | Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase). |
| ANT | Peroxisomal adenine nucleotide transporter that includes the peroxisomal membrane protein PMP34 (Solute carrier family 25 member 17). |
| APX | Encodes a putative peroxisomal ascorbate peroxidase that scavenges H2O2 into peroxisomes and prevents oxidative damage. |
| ATG11 | Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation. |
| ATG2 | Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking. |
| BAAT | Bile acid Coenzyme A: amino acid N-acyltransferase |
| CAT | Catalase (EC 1.11.1.6). |
| CCDC33 | Coiled-coil domain containing 33 |
| CHY | 3-Hydroxyisobutyryl-coenzyme A hydrolase / CoA-thioester hydrolase (CHY1) |
| CPK | A calcium-dependent protein kinase that can phosphorylate phenylalanine ammonia lyase (PAL), a key enzyme in pathogen defense. |
| CRAT | Carnitine O-acetyltransferase (EC 2.3.1.7) (Carnitine acetylase) (CAT) (Carnitine acetyltransferase) (CrAT). |
| CROT | Peroxisomal carnitine O-octanoyltransferase (EC 2.3.1.137) (COT). |
| CS | Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle. |
| DAO | D-amino-acid oxidase (EC 1.4.3.3) (DAMOX) (DAO) (DAAO). |
| DDO | D-aspartate oxidase (EC 1.4.3.1) (DASOX) (DDO). |
| DHRS4 | Dehydrogenase/reductase SDR family (NADPH- dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) . |
| DJP1 | DnaJ (Hsp40) homolog, subfamily C, member 10. |
| DNM | Dynamin 1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) |
| ECH | Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) |
| EHHADH | Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]. |
| EPHX2 | Epoxide hydrolase 2 (EC 3.3.2.3) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) |
| FACL | Acyl-CoA synthetase long-chain family. |
| FAR | Fatty acyl CoA reductase that reduces fatty acids to fatty alcohols. Male sterility domain containing. |
| FBPA | Fructose-bisphosphate aldolase, glycosomal. |
| FH | Fumarate hydratase class I. |
| FIS1 | Mitochondrial and peroxisomal protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division. |
| FNDC5 | Fibronectin type III domain containing 5 |
| FR | NADH-dependent fumarate reductase. |
| G6PDH | Glucose-6-phosphate 1-dehydrogenase. |
| G6PI | Glucose-6-phosphate isomerase, glycosomal. |
| GAPDH | Glyceraldehyde 3-phosphate dehydrogenase. |
| GGT | A glyoxylate aminotransferase protein localized to the peroxisome and thought to be involved in photorespiration/ metabolic salvage pathway. |
| GK | Glycerol kinase glycosomal |
| GNPAT | Dihydroxyacetone phosphate acyltransferase (EC 2.3.1.42) (DHAP-AT) (DAP-AT) (Glycerone-phosphate O-acyltransferase) (Acyl- CoA:dihydroxyacetonephosphateacyltransferase). |
| GOT | Cytosolic aspartate aminotransferase, involved in nitrogen metabolism. |
| GPD | Glycerol-3-phosphate dehydrogenase |
| GPK | Glyoxysomal protein kinase |
| GSTK1 | Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (Glutathione S-transferase subunit 13) (GST class-kappa) (GSTK1-1) . |
| GTO | Omega-class glutathione transferase. |
| HAO | Hydroxyacid oxidase. ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long- chain L-2-hydroxy acid oxidase). |
| HK | Hexokinase. |
| HMGCL | Hydroxymethylglutaryl-CoA lyase, (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase). |
| HPCL2 | 2-Hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL). |
| HPR | Glycerate dehydrogenase / NADH-dependent hydroxypyruvate reductase |
| HSD17B4 | Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.-); 3- hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]. |
| HXGPRT | Hypoxanthine-guanine phosphoribosyltransferase. |
| I5PDH | Inosine-5-monophosphate dehydrogenase. |
| IDE | Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease). |
| IDH | Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP). |
| IDI | Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (IPP isomerase 1) (Isopentenyl pyrophosphate isomerase 1) (IPPI1). |
| INOS | Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NOS) (iNOS). |
| INP1 | Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance. |
| LONP | Peroxisomal lon protease |
| LYS1 | Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway. |
| LYS4 | Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway. |
| MDAR | Encodes a peroxisome membrane-bound monodehydroascorbate reductase, involved in the ascorbate-glutathione cycle which removes toxic H2O2. |
| MDH | Malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle. |
| MLS | Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression. |
| MLYCD | Malonyl-CoA decarboxylase, (EC 4.1.1.9) (MCD). |
| MOSC2 | Fe-S protein with 1 predicted TMD that contains a MOSC N-terminal ? barrel domain and was found to be localized in the inner mitochondrial |
| MPV17 | MPV17-Domain bearing proteins |
| MVK | Mevalonate kinase (EC 2.7.1.36) (MK). |
| MYA2 | Myosin heavy chain (MYA2) |
| NUDT12 | Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12). |
| NUDT19 | Nudix (nucleoside diphosphate linked moiety X)-type motif 19. |
| NUDT7 | Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7). |
| OPDC-PRT | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase |
| OPR | 12-Oxophytodienoate reductase 3 (EC 1.3.1.42) (12-oxophytodienoate-10,11-reductase 3) (OPDA-reductase 3) (Delayed dehiscence 1) (AtOPR3) |
| PAOX | Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase). |
| PDCR | Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34) (2,4-dienoyl-CoA reductase 2) (pDCR). |
| PECR | Peroxisomal trans-2-enoyl-CoA reductase (EC 1.3.1.38) (TERP) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP). |
| PEN2 | Encodes a glycosyl hydrolase that localizes to peroxisomes and acts as a component of an inducible preinvasion resistance mechanism. |
| PEPCK | Glycosomal phosphoenolpyruvate carboxykinase |
| PEX1 | Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1). |
| PEX10 | Peroxisome assembly protein 10 (Peroxin-10) (RING finger protein 69). |
| PEX11 | Peroxisomal membrane protein 11 (Peroxin-11) (Peroxisomal biogenesis factor 11) . |
| PEX12 | Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3). |
| PEX13 | Peroxisomal membrane protein PEX13 (Peroxin-13). |
| PEX14 | Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein). |
| PEX15 | Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly. |
| PEX16 | Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16). |
| PEX17 | Peroxisomal membrane protein component of the peroxisomal translocation machinery, required for peroxisome biogenesis, binds Pex14p. |
| PEX18-21 | Part of a two-member peroxin family (Pex18p and Pex21p) specifically required for peroxisomal targeting of the Pex7p peroxisomal signal recognition factor and PTS2 peroxisomal matrix proteins. |
| PEX19 | Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (33 kDa housekeeping protein). |
| PEX2 | Peroxisomal membrane protein 2. Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (35 kDa peroxisomal membrane protein) (RING finger protein 72). |
| PEX20 | Peroxisomal membrane protein 20 |
| PEX22 | Peroxisomal membrane protein 20. Peroxisomal membrane protein required for import of peroxisomal proteins. |
| PEX23 | Peroxisomal membrane protein 23 |
| PEX24 | Peroxisomal membrane protein 24 |
| PEX25-27 | Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number. |
| PEX26 | Peroxisomal membran protein 26. Peroxisome assembly protein 26 (Peroxin-26). [Source:Uniprot/SWISSPROT;Acc:Q7Z412] |
| PEX3 | Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3). |
| PEX33 | Peroxisomal membrane protein PEX13, Peroxin-13. |
| PEX4 | Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis. |
| PEX5 | Peroxisome membrane protein 5 and PEX5-related protein. |
| PEX6 | Peroxisome membrane protein. Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6). |
| PEX7 | Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7). |
| PEX8 | Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5. |
| PFK | 6-Phospho-1-fructokinase. |
| PHYH | Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC 1.14.11.18) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase). |
| PIPOX | Peroxisomal sarcosine oxidase (EC 1.5.3.1) (PSO) (L-pipecolate oxidase) (EC 1.5.3.7) (L-pipecolic acid oxidase). |
| PMP52 | Integral membrane protein of 52 kDa with 5 predicted TMDs |
| PMVK | Phosphomevalonate kinase (EC 2.7.4.2) (PMKase). |
| PNC1 | Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction. |
| POMC | pro-opiomelanocortin preproprotein. |
| PRDX1 | Peroxiredoxin 1 (EC 1.11.1.15) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Proliferation-associated protein PAG) (Natural killer cell enhancing factor A) (NKEF-A). |
| PRDX5 | Peroxiredoxin 5 |
| PTE1 | Peroxisomal acyl-coenzyme A thioester hydrolase 1 (EC 3.1.2.2) (Peroxisomal long-chain acyl-coA thioesterase 1) (HIV-Nef associated acyl coA thioesterase) (Thioesterase II) (hTE) (hACTEIII) (hACTE-III) (PTE-2). |
| PTE2 | Peroxisomal acyl-coenzyme A thioester hydrolase 2a (EC 3.1.2.2) (Peroxisomal long-chain acyl-coA thioesterase 2) (ZAP128) (CTE-Ia). |
| PXMP2 | Peroxisomal membrane protein (PMP22) is a major component of peroxisomal membranes. PMP22 seems to be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane. |
| PXMP4 | Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein). |
| PXT1 | Peroxisomal, testis specific 1 |
| PYR-PDK | Pyruvate phosphate dikinase. |
| RHO1 | Rho-related GTP-binding protein RhoC (H9). |
| SCPX | Sterol carrier protein 2 (SCP-2), Sterol carrier protein X (SCP-X) (SCPX). |
| SERHL | Serine hydrolase-like protein 2 (EC 3.1.-.-). |
| SHBP | sedoheptulose-1,7-bisphosphatase |
| SLC22A21 | Organic cation/carnitine transporter 2 (Solute carrier family 22 member 5) (High-affinity sodium-dependent carnitine cotransporter). |
| SOD1 | Superoxide dismutase 1 |
| SOD2 | Superoxide dismutase 2. |
| SOX2 | Sulfite oxidase. Oxidoreductase molybdopterin binding domain. |
| STR3 | Cystathionine beta-lyase, converts cystathionine into homocysteine. |
| TPI | Triosephosphate isomerase. |
| TPN | Tryparedoxin |
| TPX | Tryparedoxin peroxidase |
| TR | Trypanothione reductase. |
| TRIM37 | Tripartite motif protein 37 (Mulibrey nanism protein). |
| UDPgal-epi | UDP-galactose 4-epimerase. |
| UGP | UDP Glucose pyrophosphoylase |
| UOX | Urate oxidase. |
| VLACS | Solute carrier family 27 (fatty acid transporter). |
| VPS1 | GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization. Involved in regulating peroxisome biogenesis. |
| XDH | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC 1.17.1.4) (XD); Xanthine oxidase (EC 1.17.3.2) (XO) (Xanthine oxidoreductase)]. |
| XPRT | Hypoxanthine-guanine phosphoribosyltransferase. |
| YOR084W | Putative lipase of the peroxisomal matrix. |
| ZADH2 | zinc binding alcohol dehydrogenase, domain containing 2 |